Lipid nanoceuticals: Current status and future perspective
Jasjeet Kaur Narang1★★ Corresponding author
- 1Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab, INDIA.
CORRESPONDENCE
Jasjeet Kaur Narang
Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab, INDIA.
Volume 4, Issue 3 · pp. 107–108 · PUBLISHED · DOI: 10.4103/2230-973X.138337
ABSTRACT
Administration of lipophilic drugs by oral route is a challenging task due to multiple factors which include poor solubilization of a drug in the gastrointestinal tract, P-glycoprotein efflux, significant first pass elimination attributed to predisposition through cytochrome P450 enzymes, all of which result in poor vivo bioavailability. Over the recent years, research has been directed toward the design of lipid-based carrier systems for delivery of hydrophobic drugs. These formulations comprise of a suitable combination of natural lipids with surfactants, cosurfactants and cosolvents.[1]
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Narang, J. K. (). Lipid nanoceuticals: Current status and future perspective. International Journal of Pharmaceutical Investigation, 4(3), 107–108. https://doi.org/10.4103/2230-973X.138337