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International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 4, issue 4 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 4, Issue 4

· pp. 149–232 · 9 articles

Volume
4
Issue
4
Published
Pages
149–232
Articles
9
Sections
2
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal Research Article

In this issue

Review Article

  1. Review

    A perspective overview on lipospheres as lipid carrier systems

    Thushara Bindu Dudala, Prasanna Raju Yalavarthi, Harini Chowdary Vadlamudi, Jyotsna Thanniru, Gowri Yaga, Naga Lakshmi Mudumala, Vivek Kumar Pasupati

    pp. 149–155 · DOI: 10.4103/2230-973X.143112 · Published

    Both hydrophilic and lipophilic therapeutics can be delivered successfully into deep and peripheral tissues such as cerebrospinal fl uid and central nervous system by encapsulating them with crystalline lipids as liposph…

Original Research Article

  1. Article

    Targeting silymarin for improved hepatoprotective activity through chitosan nanoparticles

    Swati Gupta, Shailendra Kumar Singh, Priti Girotra

    pp. 156–163 · DOI: 10.4103/2230-973X.143113 · Published

    Introduction:Silymarin is one of the best known hepatoprotective drugs, which is obtained from the seeds of Silybum marianum L., Family: Asteraceae or Compositae. The plant has traditionally been used for centuries as a …

  2. Article

    Investigation of moxifl oxacin loaded chitosan–dextran nanoparticles for topical instillation into eye: In-vitro and ex-vivo evaluation

    Raad A. Kaskoos

    pp. 164–173 · DOI: 10.4103/2230-973X.143114 · Published

    Introduction:Management of ocular surface disease by conventional formulation is limited by poor residence of drug at cul-de-sac of eye. To overcome this limitation, prolonged released mucoadhesive chitosan (CS)–dextran …

  3. Article

    Formulation and evaluation of fast dissolving tablet containing domperidone ternary solid dispersion

    Dasharath M. Patel, Sweeti P. Patel, Chhagan N. Patel

    pp. 174–182 · DOI: 10.4103/2230-973X.143116 · Published

    Introduction:Fast dissolving tablet containing domperidone ternary solid dispersion was developed to improve the dissolution of drug and stability of solid dispersion. Materials and Methods:Binary and ternary solid dispe…

  4. Article

    Role of various natural, synthetic and semi-synthetic polymers on drug release kinetics of losartan potassium oral controlled release tablets

    J. Jayasree, S. Sivaneswari, G. Hemalatha, N. Preethi, B. Mounika, S. Vasudeva Murthy

    pp. 183–188 · DOI: 10.4103/2230-973X.143118 · Published

    Objectives:The objective of the present work was to formulate and to characterize controlled release matrix tablets of losartan potassium in order to improve bioavailability and to minimize the frequency of administratio…

  5. Article

    Formulation and characterization of hydrochlorothiazide solid lipid microparticles based on lipid matrices of Irvingia fat

    Chukwuma O. Agubata, Salome A. Chime, Franklin C. Kenechukwu, Ifeanyi T. Nzekwe, Godswill C. Onunkwo

    pp. 189–194 · DOI: 10.4103/2230-973X.143120 · Published

    Introduction:The purpose of this study was to improve the solubilization, bioavailability, and permeability of hydrochlorothiazide (HCTZ) by the formulation and characterization of HCTZ solid lipid microparticles (SLMs) …

  6. Article

    Development of self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system of telmisartan

    Parul Jaiswal, Geeta Aggarwal, Sasidharan Leelakumari Harikumar, Kashmir Singh

    pp. 195–206 · DOI: 10.4103/2230-973X.143123 · Published

    Objectives:Self-microemulsifying drug delivery system (SMEDDS) and solid-SMEDDS of telmisartan was aimed at overcoming the problems of poor solubility and bioavailability. Methodology:The formulation strategy included se…

  7. Article

    Isolation, characterization, and evaluation of Cassia fi stula Linn. seed and pulp polymer for pharmaceutical application

    Suresh G Killedar, Ashwini B Nale, Harinath N More, Sameer J Nadaf, Anuja A Pawar, Umarfarukh S Tamboli

    pp. 215–225 · DOI: 10.4103/2230-973X.143128 · Published

    Introduction: Present work, is an effort toward exploring the potential of Cassia fi stula Linn. seed gum as an extended release polymer and laxative. While, C. fi stula pulp polymer has evaluated as suspending agent. Ma…

  8. Article

    Design, formulation, and evaluation of novel sustain release bioadhesive in-situ gelling ocular inserts of ketorolac tromethamine

    Jayesh K. Jethava, Gaurang K. Jethava

    pp. 226–232 · DOI: 10.4103/2230-973X.143131 · Published

    Introduction: The eye is an interesting organ. The tear fl ow and blinking refl ex maintains a good environment and removes foreign material from the eye. Several polymeric systems have been used to fabricate ocular inse…