Volume 10, Issue 2

M. K. Unnikrishnan

pp. 45–6 · DOI: 10.4103/jpp.JPP_40_19 · 2019

Medicine is a science of uncertainty and an art of probability. — William Osler Animal models occupy a central position in drug discovery. In vivo experiments are the sine qua non for identifying basic pathophysiological…

Himanshi Khera, Anupam Awasthi, Sidharth Mehan

pp. 47–56 · DOI: 10.4103/jpp.JPP_8_19 · 2019

Aim: To investigate the myocardial preconditioning potential of hedgehog activator smoothened (SMO) receptor agonist purmorphamine (PUR) against ischemia‑reperfusion (I/R) injury in deoxycortisone acetate (DOCA) salt‑ind…

Sandip Roy Basunia, Baisakhi Laha, Avijit Hazra

pp. 57–62 · DOI: 10.4103/jpp.JPP_6_19 · 2019

Aim: To compare the post-operative analgesic effect of of buprenorphine 20 µg/h patch with diclofenac 75 mg intramuscular injection following upper abdominal surgery under general anesthesia (GA). Materials and Methods: …

Chandini Rao, Varadaraj Shenoy, Padmaja Udaykumar

pp. 63–68 · DOI: 10.4103/jpp.JPP_27_19 · 2019

Aim: To identify and evaluate the potential drug–drug interactions (PDDI) in hospitalized patients in a pediatric intensive care unit (PICU). Materials and Methods: In this cross‑sectional observational study, we analyze…

Shalini Chawla, Ankur Tiwari, Shariq Naeem Syed

pp. 69–74 · DOI: 10.4103/jpp.JPP_105_18 · 2019

Aim: To assess the patterns of dermatological adverse drug reactions (ADRs) and drugs responsible to formulate a strategy for prevention and treatment using a new app. Materials and Methods: In the present study, 870 pat…

Md. Shahid Alam, Ashwin Cherusheril Somarajan

pp. 75–6 · DOI: 10.4103/jpp.JPP_31_19 · 2019

The use of systemic and topical steroids, amiodarone, and phenothiazines has been established as risk factors for the development of cataract. Antihistaminics are commonly prescribed drugs for a wide range of allergic di…