Volume 9, Issue 1

Sheba Rani David, Nora Syahirah Sawal, Muhammad Nur Salam Bin Hamzah, Rajan Rajabalaya

pp. 1–5 · DOI: 10.4103/jpp.JPP_79_17 · 2018

Methemoglobinemia is a blood disorder in which there is an abnormal amount of methemoglobin (MetHb) formation, thus unable to release oxygen effectively to body tissues. This is mainly because MetHb is the altered state …

Jaykaran Charan, Jatin V. Dhanani, Maulik Sumantbhai Doshi, Tea Reljic, Athanasios Tsalatsanis, Ambuj Kumar

pp. 6–10 · DOI: 10.4103/jpp.JPP_168_17 · 2018

Objectives: To assess the correlation between drug approval and disease burden in India. Materials and Methods: A cross sectional study was conducted and data on drug approval for the past 14 years (2000–2013) were downl…

Bhuvanesh Sukhlal Kalal, Vinitha Ramanath Pai, Dinesh Upadhya

pp. 11–6 · DOI: 10.4103/jpp.JPP_129_17 · 2018

Objectives: To evaluate the beneficial effect of treating tumor cells with valproic acid (VPA) in combination with inhibitors of various downstream molecules of epidermal growth factor receptor pathway for limiting tumor…

Olga A. Ovsyannikova

pp. 17–20 · DOI: 10.4103/jpp.JPP_196_16 · 2018

Objective: To investigate the state of femoral red bone marrow microvasculature of nonlinear white male rats in the course of an acute experiment. Materials and Methods: The ontogenesis of experimental animals were betwe…

Jayesh Dalpatbhai Solanki, Kruti J. Patel, Nisha Lalwani, Hemant B. Mehta, Chinmay J. Shah, Matika N. Lakhtaria

pp. 21–26 · DOI: 10.4103/jpp.JPP_139_17 · 2018

Objectives: To study the electrocardiogram (ECG) based QT parameters namely QTc (heart rate corrected QT), QTd (QT dispersion) in treated type 2 diabetics (T2D) and the effect of hypertension (HTN), blood pressure (BP) c…

Arijit Ghosh, Kapildev Das

pp. 27–31 · DOI: 10.4103/jpp.JPP_20_18 · 2018

Objective: To compare the efficacy and safety of nadifloxacin and benzoyl peroxide versus adapalene and benzoyl peroxide in acne vulgaris. Materials and Methods: Patients fulfilling the inclusion criteria were divided in…

Durai Murugan Muniswami, Bashir Ahmed, George Tharion

pp. 32–39 · DOI: 10.4103/jpp.JPP_173_17 · 2018

Objective: To compare the efficacy of individual and combined treatment of olfactory ensheathing cells (OECs) and acidic fibroblast growth factor (aFGF) in a rat model of spinal cord injury (SCI). Materials and Methods: …

Kamaldeep Sadh, Pooja Shatadal, Ekta Franscina Pinto, Sachin Nagendrappa, Harish M. Tharayil, Chittaranjan Andrade

pp. 42–42 · DOI: 10.4103/jpp.JPP_27_18 · 2018

Arshad Basha Shaik, Mukhyaprana Prabhu, Smita Shenoy, Sereen Rose Thomson

pp. 43–5 · DOI: 10.4103/jpp.JPP_121_17 · 2018

Oseltamivir is a viral neuraminidase enzyme inhibitor commonly prescribed for prevention and management of influenza. Common adverse effects of oseltamivir are gastrointestinal side effects such as nausea, vomiting, diar…

Vybhava Krishna, Sadhana N. Holla, Sweenly V. Sunny, Srikiran A. Hebbar

pp. 46–8 · DOI: 10.4103/jpp.JPP_152_17 · 2018

Toxic epidermal necrolysis (TEN) is a rare, but serious condition characterized by widespread death of epidermis involving skin and mucous membrane. Ceftriaxone‑induced TEN in the pediatric age group is rare. Hereby, we …

Vinayaka Anuhya, Sharath Madhyastha, Veena Nayak, Gangaparameswari Soundarrajan, Raviraj Acharya

pp. 49–51 · DOI: 10.4103/jpp.JPP_151_17 · 2018

Warfarin is an oral anticoagulant which is a natural coumarin derivative used for the treatment of various diseases such as thromboembolic disorders, prosthetic heart valves, and atrial fibrillation. Bleeding tendencies …

Jeffrey W. Jansen, Ryan P. Moenster

pp. 52–5 · DOI: 10.4103/jpp.JPP_101_17 · 2018

Vancomycin remains the antibiotic of choice to treat resistant Gram-positive infections and is dosed utilizing weight-based protocols or pharmacokinetic calculations. Pharmacokinetic calculations are a more proactive app…

Raj, Priyadarshini

pp. 56–57 · 2018