Volume 2, Issue 1

Essential medicines for children: Should we focus on a priority list of medicines for the present?

Gitanjali B

pp. 1–2 · DOI: 10.4103/0976-500X.77073 · Published 2011

Evaluation of nootropic and neuroprotective effects of low dose aspirin in rats

Arijit Ghosh, V. R. Dhumal, A. V. Tilak, Nina Das, Amarinder Singh, Abhijit A. Bondekar

pp. 3–4 · DOI: 10.4103/0976-500X.77079 · Published 2011

Objective: To evaluate the nootropic and neuroprotective effects of aspirin in Sprague Dawley rats. Materials and Methods: Retention of conditioned avoidance response (CAR) and central 5-HT-mediated behavior (lithium-ind…

Pharmacokinetic and pharmacodynamic drug interactions of carbamazepine and glibenclamide in healthy albino Wistar rats

S. Prashanth, A. Anil Kumar, B. Madhu, N. Rama, J. Vidya Sagar

pp. 7–8 · DOI: 10.4103/0976-500X.77083 · Published 2011

Aims: To find out the pharmacokinetic and pharmacodynamic drug interaction of carbamazepine, a protype drug used to treat painful diabetic neuropathy with glibenclamide in healthy albino Wistar rats following single and …

Effects of fluoxetine and escitalopram on C-reactive protein in patients of depression

Nilesh Chavda, N. D. Kantharia, Jaykaran Jaykaran

pp. 11–12 · DOI: 10.4103/0976-500X.77091 · Published 2010

Objective: To study the anti-inflammatory activity of fluoxetine and escitalopram in newly diagnosed patients of depression and also to evaluate the association between depression and inflammation. Materials and Methods:…

The incidence and nature of drug-related hospital admission: A 6-month observational study in a tertiary health care hospital

Harminder Singh, Bithika Nel Kumar, Tiku Sinha, Navin Dulhani

pp. 17–18 · DOI: 10.4103/0976-500X.77095 · Published 2011

Objective: To assess and evaluate the frequency, severity and classification of drug-related problems (DRP) resulting in hospitalization in an internal medicine department of a large tertiary care hospital and to identif…

Adverse drug reactions in inpatients of internal medicine wards at a tertiary care hospital: A prospective cohort study

Mukeshkumar B. Vora, Hiren R. Trivedi, Bharatbhai K. Shah, C. B. Tripathi

pp. 21–22 · DOI: 10.4103/0976-500X.77102 · Published 2011

Objective: To find out incidence of adverse drug reactions (ADR) in patients of internal medicine wards and study various aspects of ADR, e.g., causality, mortality, drugs commonly causing ADR in internal medicine wards …

Adverse drug reactions of nonsteroidal anti-inflammatory drugs in orthopedic patients

Alpa Pragnesh Gor, Miti Saksena

pp. 26–27 · DOI: 10.4103/0976-500X.77104 · Published 2011

Objectives: To identify the ADRs due to NSAIDs and to know how to monitor the drug’s effect. Materials and Methods: A descriptive study was undertaken in the Orthopedic Outpatients Department of a tertiary care teaching …

Pharmacological evidences for the stimulation of calcium-sensing receptors by nifedipine in gingival fibroblasts

Toshimi Hattori, Toshiaki Ara, Yoshiaki Fujinami

pp. 30–35 · DOI: 10.4103/0976-500X.77111 · Published 2011

Objective: To investigate pharmacologically whether CaSRs are involved in the Ca2+ antagonist-induced [Ca2+]i elevation in gingival fibroblasts. Materials and Methods: Gin-1 cells, normal human gingival fibroblasts, were…

Protocol for middle cerebral artery occlusion by an intraluminal suture method

Rupadevi M., Parasuraman S., Raveendran R.

pp. 36–37 · DOI: 10.4103/0976-500X.77113 · Published 2011

Atorvastatin-induced acute pancreatitis

Prasanna R. Deshpande, Kanav Khera, Girish Thunga, Manjunath Hande, Siddalingana T. G. Gouda, Anantha Naik Nagappa

pp. 40–42 · DOI: 10.4103/0976-500X.77114 · Published 2011

Atorvastatin-induced acute pancreatitis (AP) is one of the rare adverse effects available in the literature. We report a case of 53-year-old patient developed AP after treatment with atorvastatin monotherapy which resolv…

Critical appraisal of irrational drug combinations: A call for awareness in undergraduate medical students

Shilpa P Jadav, Dinesh M Parmar

pp. 45–46 · DOI: 4103/0976-500X.77117 · Published 2011

2. Tom L. Twenty statistical error even you can find in biomedical research articles. Croat Med J 2004;45:361-70.

Jaykaran

pp. 126–127 · DOI: 10.4103/0976-500X.77115 · Published 2011

Fingolimod (FTY720): First approved oral therapy for multiple sclerosis

Sushil Sharma, A G Mathur, Sapna Pradhan, D B Singh, Sparsh Gupta

pp. 49–51 · DOI: 10.4103/0976-500X.77118 · Published 2011

Prediction of activity spectra for substances

Parasuraman S.

pp. 52–53 · DOI: 10.4103/0976-500X.77119 · Published 2011

The biological activity spectrum (BAS) is an intrinsic property of a compound that is representative of different pharmacological effects, physiological and biochemical mechanisms of action and specific toxicity (mutagen…

Frequency distribution

Manikandan S

pp. 54–56 · DOI: 10.4103/0976-500X.77120 · Published 2011

Gout drug “could treat angina”

Sivagnanam G

pp. 57–58 · DOI: 10.4103/0976-500X.77121 · Published 2011

ERRATUM

pp. 58–58 · DOI: · Published 2011

Research Methodology Simplified Every Clinician a Researcher

T. Kadhiravan

pp. 59–59 · DOI: · Published 2011