jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Journal of Young PharmacistsNOW IN
Review

Ascertaining the Paradigm of Secondary Metabolism Enhancement through Gene Level Modification in Therapeutic Plants

Swati Sinha1, Kajal Sandhu1, Neema Bisht1, Tapan Naliwal1, Ishan Saini2, Prashant Kaushik3★★ Corresponding author

  1. 1Department of Biotechnology, Kumaun University, Bhimtal Campus, Bhimtal, INDIA.
  2. 2Department of Botany, Kurukshetra University, Kurukshetra, INDIA.
  3. 3Instituto de Conservación y Mejora de la Agrodiversidad Valenciana, Universitat Politècnica de València, Valencia, SPAIN.

CORRESPONDENCE

Prashant Kaushik

Instituto de Conservación y Mejora de la Agrodiversidad Valenciana, Universitat Politècnica de València, Valencia, SPAIN.

prakau@doctor.upv.es

Received: 04-09-2019; Revised: 05-10-2019; Accepted: 24-10-2019.

Volume 11, Issue 4 · pp. 337–343 · PUBLISHED · DOI: 10.5530/jyp.2019.11.70

View on JYP original site ↗

ABSTRACT

Since ages plants with therapeutic effects are used for curing several human ailments. With the development in modern biotechnological tools, these therapeutic compounds could be overexpressed in the plants. This review aims to compile the valuable information from the examples in the literature, regarding the biotechnological tools those could be useful for the overproduction of health-promoting biochemicals in the medicinal plants. Gene level modification is all about creating improved variety of plants that are highly resistant to pests and pesticides or contain higher levels of nutrients than conventional plants. Plant secondary metabolites constitute an exciting and vital aspect of research, due to their chemical diversity, varied biological functions and pharmacological activities. Gene modification, through Agrobacterium mediated transformation, RNA interference or CRISPER/Cas9, has opened avenues of improvement in medicinal plants and provide an alternative production system of pharmaceutically important secondary metabolites for their commercial exploitation.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Sinha, S., Sandhu, K., Bisht, N., Naliwal, T., Saini, I., & Kaushik, P. (). Ascertaining the Paradigm of Secondary Metabolism Enhancement through Gene Level Modification in Therapeutic Plants. Journal of Young Pharmacists, 11(4), 337–343. https://doi.org/10.5530/jyp.2019.11.70