Volume 14, Issue 1

M Sai Mounika, Ramesh Ganpisetti, Ketham Giribabu, Ritika Rana, G Sanjay, Indraneel Bag

pp. 1–5 · DOI: 10.5530/jyp.2022.14.1 · 2022

Animal models are the most commonly used model that helps to improve the understanding of the genetic alterations that occur in humans during the carcinogenic environment. Furthermore, these models play a pivotal role in…

Talasila Bhanu Teja, Mahendran Sekar, Talasila Pallavi, Sivamma Mettu, TE Gopalakrishna Murthy, Nur Najihah Izzati Mat Rani, Pallaval Veera Bramhachari, Srinivasa Reddy Bonam

pp. 6–14 · DOI: 10.5530/jyp.2022.14.2 · 2022

Artificial Neural Networks (ANN) are becoming the tool of choice for the pharmaceutical industry due to their ability to mimic the brain’s way of functioning. Computational and statistical methods have recently sparked t…

Maurya Rahul, Thirupataiah Boini, Misro Lakshminarayana, Thulasi Radhakrishnan, Rohit Kolangarakalam Sudayadas

pp. 15–20 · DOI: 10.5530/jyp.2022.14.3 · 2022

Andrographolide (AGL) is an active phytoconstituent of Andrographis paniculata, which is chemically a diterpenoid lactone ring. The various pharmacological activities of this compound are reported but a clinically remark…

Jamunarani Appalasamy, Amutha Selvaraj, Siva Seeta Ramaiah

pp. 21–24 · DOI: 10.5530/jyp.2022.14.4 · 2022

Stroke is among the most significant disease burden globally, with upper middle-income countries having the highest prevalence. Worldwide stroke burden is credited to modifiable risk factors related to underlying comorbi…

Fernanda Matias de Carvalho, Lidia Audrey Rocha Valadas, Joseph Anderson Sá Nogueira, Patrícia Leal Dantas Lobo, Fernanda Leal Dantas Sales Pimentel, Marina Sena Lopes da Silva Sacchetto, Emmanuel Arraes de Alencar Júnior, Arkila Pinheiro Rodrigues de Sousa, Sarah Gabrielle Sousa de Oliveira Rodrigues, Pollyanna Bitu de Aquino

pp. 25–29 · DOI: 10.5530/jyp.2022.14.5 · 2022

To review in the literature the relationship between lactation, deleterious bucal habits and malocclusion. For this literature review, scientific articles were searched in databases such PubMed and SciELO, in English and…

José Artur Oliveira Pereira, Mariana Dantas Do Nascimento, Edilson Martins Rodrigues Neto, Fernanda Maria Teófilo Campos, Francisco César Monteiro Chaves Filho, Fernanda Dantas Sales Pimentel, Cristiane Sá Roriz Fonteles, Patricia Leal Dantas Lobo

pp. 30–32 · DOI: 10.5530/jyp.2022.14.6 · 2022

Zikavirus infection during pregnancy generates a series of neurological, musculoskeletal and sensory disorders known as Congenital Zika Virus Syndrome (CZVS), being responsible for even oral changes. This study aims to r…

Sandeep DS, Sowmya CR, Anoop Narayanan V, Gowrav MP

pp. 33–36 · DOI: 10.5530/jyp.2022.14.7 · 2022

Objectives: The present study describes the generic drug regulations and registration process in three ASEAN countries Indonesia, Malaysia and Vietnam. Methods:For the current study, the information has been taken from g…

BM Gupta, KK Mueen Ahmed

pp. 37–45 · DOI: 10.5530/jyp.2022.14.8 · 2022

Objectives:The study presents a bibliometric assessment of COVID-19 vaccine research publications to understand the current and up-to-date scenario of COVID-19 vaccine research and to track important research players and…

Gururaja MP, Anjali Krishna M, Himanshu Joshi

pp. 46–49 · DOI: 10.5530/jyp.2022.14.9 · 2022

Objectives: The present study was conducted to evaluate the anxiolytic potential of ethanolic leaf extract of Tinospora cordifolia Linn. Tinospora cordifolia, the versatile herbal drug is the distinctive source of consti…

Khatoon Rizwana, Aslam Mohammad, Chaudhary Shahid Shah, Nazeem Fahamiya, Mohamed Shiffa

pp. 50–55 · DOI: 10.5530/jyp.2022.14.10 · 2022

Background:Nephrotoxicity is an emerging health issue in many countries due to exogenous or endogenous toxicants. Many drugs are responsible for causing renal damage including antibiotics such as aminoglycoside, cisplati…

Manjir Sarma Kataki, Bibhuti Bhusan Kakoti

pp. 56–61 · DOI: 10.5530/jyp.2022.14.11 · 2022

Objectives:In this present study the hepatoprotective effect of an optimized herbal formula (HF) was appraised against paracetamol induced liver damage in rats. Methods: In vitro antioxidant activity of the HF was evalua…

Vikas Suresh Shende, Jagdish Labhubhai Kakadiya

pp. 62–66 · DOI: 10.5530/jyp.2022.14.12 · 2022

Objectives:To investigate the acute and subacute oral toxicity of ethanol and chloroform extracts Solanum giganteum Jacq (SG) leaves in a rodent for evaluating its safety profile. Methods: Solanum giganteum Jacq leaves e…

Nazeem Fahamiya, Shafeek G Ansari, Ansari ZA, Mohammad Aslam, Zakir Mohammad, Mohamed Shiffa, Mohammad Zahid Ashraf

pp. 67–72 · DOI: 10.5530/jyp.2022.14.13 · 2022

Background: Kushta Gaodanti (KG) is an essential Unani dosage form prepared by calcination according to classical texts. Standardization is paramount important to check purity and genuineness of the product. However, the…

Vijaybhanu Perumalsamy, Harish Kumar DR, Sarasija Suresh

pp. 73–76 · DOI: 10.5530/jyp.2022.14.14 · 2022

Background:Curcumin, chemically difeluroyl methane is a yellow polyphenol isolated from the rhizomes of perennial herb Curcuma longa. It has been shown highly cytotoxic towards various cancer cell lines but its water ins…

Ramakrishna Chintakunta, GV Subbareddy

pp. 77–81 · DOI: 10.5530/jyp.2022.14.15 · 2022

Background:Ofloxacin is a fluoroquinolone antibiotic very useful in the treatment of several bacterial infections. The Thiazolidinone ring system represents a privileged structure in drug discovery. multi-drug-resistant …

Badikela Ramakrishna, Sumanta Mondal, Prasenjit Mondal

pp. 82–88 · DOI: 10.5530/jyp.2022.14.16 · 2022

Objectives: The present method was developed for the estimation of palbociclib in spiked human plasma using Liquid chromatographic mass spectroscopy. Methods: The liquid-liquid extraction method was adopted and chromatog…

Mukhtar Ansari, Farhan Alshammari, Hassan Alqahtani, Raad Alshammari, Mohammed Althubyani, Turki Al Hagbani, Bushra Alshammari

pp. 89–92 · DOI: 10.5530/jyp.2022.14.17 · 2022

Background:COVID-19 pandemic has reignited interest in online education as an appealing alternative. The study’s goal was to evaluate students’ perception of using e-learning, and to identify drivers and barriers the stu…

Francisco Álisson Paula de França, Ana Claudia de Brito Passos, Melissa Soares Medeiros, Marta Maria de França Fonteles

pp. 93–99 · DOI: 10.5530/jyp.2022.14.18 · 2022

Objectives: To delineate the sociodemographic and clinical characteristics, sexual behavior, and the degree of adherence of users to Human Immunodeficiency Virus (HIV) Pre-Exposure Prophylaxis (PrEP), as well as the fact…

Manisha Saini, Minakshi Rana, Karun Bhatti, Rina Das, Dinesh Kumar Mehta

pp. 100–105 · DOI: 10.5530/jyp.2022.14.19 · 2022

Background:Health-related quality of life has become an important aspect in the field of healthcare as an important outcome measure for chronic diseases like hypertension. Improvement in HRQoL have become a focal point i…

Ahmad Thouseef K H, Bharath Raj K C, Shricharith Shetty, Shreyas K, Sinchana R Shetty, Nidhi K

pp. 106–109 · DOI: 10.5530/jyp.2022.14.20 · 2022

Background: Eczema is a chronic, usual, non-infective inflammatory state characterized by intense pruritis, redness, and swelling. Eczema patients experience mild to severe systemic symptoms such as itching, pain, and sl…