Aspirin Induced Leukocytoclastic Vasculitis: Case Report

ABSTRACT

Acetyl salicylic acid is indicated for treatment and prophylaxis of many cardiovascular diseases. In some cases, it may cause cutaneous adverse reactions. In this case leukocytoclastic vasculitis was developed due to aspirin. A 70-year-old male patient had complaints of Bilateral lower limb swelling associated with swelling over scrotum and penis since 3 days. He was suffering from several medical conditions and for that he was taking multiple medications. 1 month ago, he had a cerebrovascular accident (CVA) and was taken to a private clinic where he was prescribed with a combination of Aspirin (125mg) and Atorvastatin (20mg) at the bed time (HS) (no documentation was found). He had mild renal impairment. During hospital he developed hematuria. On the 3rd day of admission, he was diagnosed with Leukocytoclastic vasculitis and admitted to ICU. Leukocytoclastic Vasculitis was suspected due to a combination of aspirin and atorvastatin and this combination drug was stopped and the patient was monitored. This dechallenge resulted in recovery of Leukocytoclastic Vasculitis. Leukocytoclastic Vasculitis may be caused by Aspirin and showed some reversible recovery of symptoms.

KEYWORDS

• Acute renal failure
• Haematuria
• Cutaneous manifestation
• Iatrogenic dermatological reaction
• Aspirin

Showing references and in-text citations exactly as published.

• DOI10.5530/jyp.2022.14.50Copy

RELATED ARTICLES

Matched on section and article type within this issue of JYP.

• Article · VOLUME 14, ISSUE 2Chronic use of Phenytoin Induced Ataxia: A Case Series of Six PatientsNiharika Pathakamuri, Sujit Kumar Sah, Atiqulla Shariff, Siddartha Ningappa Dhurappanavar, Jalapa Pradhan, Anjali Pradhan, Sai Siddharth Matad, Sinchana Shivukumar, Dibaneja Khonglein, Meghna Gosi, Veer Sangmesh Patil · pp. 249–252Case ReportSame type: Article
• Article · VOLUME 14, ISSUE 2Phenytoin Induced Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: A Case ReportMeghna Gosi, Sujit Kumar Sah, Arya Merin, Siddartha Ningappa Dhurappanavar, Ashwini Padubidri Kombettu · pp. 253–255Case ReportSame type: Article
• Article · VOLUME 14, ISSUE 2A Rare Case Report on Opsoclonus Myoclonus Syndrome Associated with a Developmental RegressionNeha Suratiya, Khevna Shah, Preya Soni, Sarvajeet Khare · pp. 256–257Case ReportSame type: Article
• Article · VOLUME 14, ISSUE 2Chronic Idiopathic Thrombocytopenic Purpura during the Pregnancy: A Case ReportKommuri Vyduryam, T Vinay Kumar, Sreya Kosanam, Shaik Asha Begum, Namala Venkata Yaseswi, Vesapogu Pravalika · pp. 261–262Case ReportSame type: Article