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Review

Medicinal Plants and Herbal Formulations Ameliorating Neurodegeneration: Remedies Combating Parkinson’s and Alzheimer’s Disease

Kumar Abhishek1, Rai Saksham1, Katiyar Deepti1, Rao NGR1, Prakash Surya1, Kumar Vinay1, Saxena Vidhu1, Bansal Priya1★★ Corresponding author

  1. 1KIET School of Pharmacy, KIET Group of Institutions, Delhi-NCR, Ghaziabad, Uttar Pradesh, INDIA.

CORRESPONDENCE

Bansal Priya

KIET School of Pharmacy, KIET Group of Institutions, Delhi-NCR, Ghaziabad, Uttar Pradesh, INDIA.

bansalpriya23@gmail.com

Received: 19-09-2022; Revised: 29-11-2022; Accepted: 20-12-2022.

Volume 15, Issue 2 · pp. 194–200 · PUBLISHED · DOI: 10.5530/jyp.2023.15.28

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ABSTRACT

Neuronal degeneration, characterized by progressive and irreversible loss of structure and function of neurons, could be a physiological age related or pathological intervention resulting in death of neuronal tissues. Neurodegenerative disease (ND) like Parkinson’s Disease (PD) and Alziemer’s Diseases (AD) aving molecular complexity in pathogenesis resulting in prominent loss of normal physiology of an individual. Practically, ND are incurable but by therapeutic approaches the loss of neurons and progress of disease is controlled but these drugs are associated with many unwanted effects. Herbals have been used from ancient times and referred to as conventional treatment methods to treat neurodegenerative disease having natural healing power and less side effects. Phytochemicals like Alkaloids, terpenes, saponins, phenols, flavonoids, etc. have major mechanisms behind management of most of the ND. In this review we briefly discussed some medicinal plants which have neuroprotective activities against ND specially AD and PD along with its mechanism of actions behind their pharmacological activities. Some herbal formulations used as traditional medicines to treat neurodegenerative disease worldwide are also briefly discussed.

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    Abhishek, K., Saksham, R., Deepti, K., NGR, R., Surya, P., Vinay, K., Vidhu, S., & Priya, B. (). Medicinal Plants and Herbal Formulations Ameliorating Neurodegeneration: Remedies Combating Parkinson’s and Alzheimer’s Disease. Journal of Young Pharmacists, 15(2), 194–200. https://doi.org/10.5530/jyp.2023.15.28