Volume 12, Issue 4

· pp. 294–391 · 19 articles

Volume: 12
Issue: 4
Published
Pages: 294–391
Articles: 19
Sections: 4
ISSN: Print - 0975-1483 | Online - 0975-1505
Journal: JYP

Review Article Original Artcile Case Report Short Communication

In this issue

Review Article

Review
Carbamazepine and its Synthesis Related Impurities Profile Compilation and its Monograph Dispute for the Best Regulatory Practice: A Review
Samrat Debnath, Jeyaprakash Mari Raju, Rupika Sunidhi Chennapragada
pp. 294–298 · DOI: 10.5530/jyp.2020.12.80 · Published
Carbamazepine (CBZ) is a widely-used anticonvulsant drug, with a high prescription rate. However, there seem to be certain inconsistencies regarding the number of reported impurities of the drug. A monograph study of the…

Original Artcile

Article
Synthesis and Anti-inflammatory Activity of 7-Non-steroidal Anti-inflammatory Drugs Substituted Flavone
Prakash Govindaraman, Mohan S, Sundararajan N, Sivasakthi R, Balachandar S
pp. 299–302 · DOI: 10.5530/jyp.2020.12.81 · Published
Aim:Inflammation shows an important character in illnesses such for example cardiovascular diseases, asthma, malignant and diabetes. Food can guidance different phases of inflammation and can have an important influence …
Article
An Injectable Sustained Release Lipid Based in situ Gel System of Aripiprazole for the Management of Schizophrenia
Ashish Raghuvanshi, Urooj Ahmed Khan, Uzma Parveen, Anshul Gupta, Gaurav Kumar Jain
pp. 303–308 · DOI: 10.5530/jyp.2020.12.82 · Published
Objectives:Development and evaluation of aripiprazole (AP) loaded lipid based in situ gel system (AP-LIGS) which could maintain the release of drug throughout period circumventing the need of oral therapy. Materials and …
Article
Development and Characterization of Kojic Acid and Carnaúba Wax-Based Solid Lipid Microparticles
Larissa Coelho Costa, Bianca Oliveira Louchard, Edilson Martins Rodrigues Neto, Priscylla da Silva Giffony, Fernanda Maria Teófilo Campos, Tamara Gonçalves de Araujo
pp. 309–313 · DOI: 10.5530/jyp.2020.12.83 · Published
Background:The treatment of dyschromia can be conducted using dermocosmetics containing depigmenting agents, such as kojic acid. Objectives:This study aimed the development and characterization of Carnaúba wax-based micr…
Article
Investigation of Polymeric Micellar Nanoparticles of Amlodipine Besylatefor Transdermal Delivery
Manesha Uthaman, Marina Koland
pp. 314–320 · DOI: 10.5530/jyp.2020.12.84 · Published
Objectives:The objective of this study was to formulate and investigate amlodipine besylate loaded polymeric micelles and their effect on enhancing transdermal permeation of the poorly water-soluble drug via transdermal …
Article
Effect of BIBN4096 in Neurobehavioural Changes of Nitroglycerin-induced Migraineous Rat Model
Anson Sunny Maroky, Varadarajan Parthasarathy
pp. 327–333 · DOI: 10.5530/jyp.2020.12.86 · Published
Background:The pathogenesis of migraine pain has not yet been adequately explained. The incidence of cognitive dysfunction and psychological symptoms, as well as their reciprocal relationships in migraine patients, is st…
Article
In vitro Immunomodulatory Effect from Edible Green Seaweed of Caulerpa lentillifera Extracts on Nitric Oxide Production and Phagocytosis Activity of RAW 264.7 Murine Macrophage Cells
Sofa Fajriah, Sri Handayani, Ellya Sinurat, Megawati Megawati, Akhmad Darmawan, Hariyanti Hariyanti, Rizna Triana Dewi, Abdi Wira Septama
pp. 334–337 · DOI: 10.5530/jyp.2020.12.87 · Published
Background:Caulerpa lentillifera is edible macroalgae which has several biological properties. This marine plant also contains beneficial secondary metabolites that can be used for treatment and prevent several deficienc…
Article
Impact of Black Garlic on Biomarkers of Arterial Stiffness and Frontal QRS-T Angle on Hypertensive Animal Model
Patonah Hasimun, Yani Mulyani, Elfiana Rehulina, Hasballah Zakaria
pp. 338–342 · DOI: 10.5530/jyp.2020.12.88 · Published
Background:Hypertension is a silent killer disease that continues to increase every year. Non-optimal treatment of hypertension may heighten the risk of dangerous cardiovascular problems. Black garlic (BG) has been known…
Article
A Study of Prescribing Errors in a Private Tertiary Care Hospital in Saudi Arabia
Abedulla Khan Kayamkani, Turki Khalid Abdullkader Bayazeed, Mohammed Salah M Aljuhani, Sami Majed Sami Koshak, Aejaz Abdullatif Khan, Syed Mohammad Shakeel Iqubal, Abdul Rahman Ikbal, Muazzam Sheriff Maqbul, Noorulla Khan Mayana, Shaik Mubashira Begum
pp. 343–347 · DOI: 10.5530/jyp.2020.12.89 · Published
Objectives:Providing a good quality and safe medical service with medicines that are both effective and safe to patients is the main objective of any health care organization. This study aims to know the types and nature…
Article
Acute Adverse Drug Reactions in Inpatient Children Diagnosed with Cancer over a 12-Year Period: A Report from a Single Center Study
Maryam Tashvighi, Yasaman Sadeghi, Narjes Mehrvar, Mohammad Faranoush, Negin Jafariyan Lahijani, Mahyar Nourian, Mardawig Alebouyeh, Azim Mehrvar
pp. 348–353 · DOI: 10.5530/jyp.2020.12.90 · Published
Objectives:In this study, we aimed to assess the incidence rate of adverse drug reactions (ADR) to chemotherapeutic agents and related problems in hospitalized pediatric patients diagnosed with cancer who referred to Mah…
Article
Exploring the Use of Computer-aided Learning Modules (CAL) to Enhance the Teaching and Learning of Pharmacokinetics to Pharmacy Students
Mumtaz Hussain, Shariza Sahudin, Izzati Yussof
pp. 354–359 · DOI: 10.5530/jyp.2020.12.91 · Published
Objectives:To develop an integrated software package to augment the teaching and learning of pharmacokinetics to undergraduate pharmacy students, covering various aspects of pharmacokinetics from basic principles, calcul…
Article
Under-reporting of Adverse Drug Reactions among Healthcare Professionals in Brazil: An Estimate Based on National Pharmacovigilance Survey
José Romério Rabelo Melo, Elisabeth Carmen Duarte, Karla de Araújo Ferreira, Yannie Silveira Gonçalves, Marcelo Vogler de Moraes, Paulo Sergio Dourado Arrais
pp. 360–365 · DOI: 10.5530/jyp.2020.12.92 · Published
Background:Adverse Drug Reaction (ADR) is a public health problem with an impact on health care costs. Spontaneous reporting comprises the primary method for detection ADR’s. However, high levels under-reporting represen…
Article
Retrospective Study of the Prevalence of Bacterial Contamination of Platelet Concentrates in Morocco
Fatna EL Mehdaoui, Saida Bouazzaoui, Abdelmajid Soulaymani, Safia Boulahdid, Karim Souly, Mimoun Zouhdi, Khadija Hajjout, Raouf Alami
pp. 366–369 · DOI: 10.5530/jyp.2020.12.93 · Published
Objective: This retrospective study was conducted using data from the 2005 to 2012 archives at the Laboratory of Bacteriology Serology and Hygiene of Ibn Sina University Hospital Center in Rabat, Morocco. Its aim is to d…
Article
Patient Initiated Side Effects Reporting System in their Vernacular Language: A Cross Sectional Analysis of Feasibility and Acceptability in Our Scenario
Krishnan Vengadaragava Chary, Karthik VP
pp. 370–372 · DOI: 10.5530/jyp.2020.12.94 · Published
Objectives:To determine the acceptability of Patient initiated side effects reporting system in their vernacular language. Methods:All the hundred participants were using simple non-probability sampling; participants wer…
Article
Pharmacotherapy Follow up in Mental Health: Which Outcomes Change in a Short Period?
Sheilla Alessandra Ferreira Fernandes, Giselle de Carvalho Brito, Chiara Erminia da Rocha, Renato Melo Torres, Aurigena Antunes de Araújo, Marta Maria de França Fonteles
pp. 373–378 · DOI: 10.5530/jyp.2020.12.95 · Published
Objectives: Investigate the outcome changes in patients with depression and anxiety during a pharmacotherapy follow up service, in a short period. Materials and Methods:A randomized and controlled trial of 70 adults was …
Article
Predictors of Perception of Mental Health Challenges among Healthcare Students in a Medical University
Muhammad Zahid Iqbal, Salah-Ud-Din Khan, Muhammad Shahid Iqbal
pp. 379–382 · DOI: 10.5530/jyp.2020.12.96 · Published
Objectives:The study objective was to appraise the predictors affecting healthcare students’ perceptions concerning mental health challenges (MHCs) in a medical university. Methods: A cross-sectional observational study …

Case Report

Article
Parenteral Cyanocobalamin Induced Arthralgia: A Case Report
Kabakama Clement Jr, Shekhar Deshpande, Shefali Deo
pp. 383–385 · DOI: 10.5530/jyp.2020.12.97 · Published
Cyanocobalamin is a presently coenzyme mainly involved in reactions leading to synthesis of Nucleic Acids and of that of methionine from homocysteine. On the other hand hematological neurological and epithelial clinical …
Article
Phenytoin Induced Erythema Multiforme
Dhamodharan Anuranjani, Selvaraj Nitya, Sivagourounadin Kiruthika
pp. 386–388 · DOI: 10.5530/jyp.2020.12.98 · Published
Phenytoin is conventional antiepileptic drug is effective in the treatment of generalized tonic-clonic seizures but its adverse effects makes its usage limited. We herein present the case of Phenytoin induced Erythema Mu…

Short Communication

Communication
Isolation of Catechins from Roscoea purpurea
Gunpreet Kaur, Vikas Gupta, RG Singhal, RK Rawal, Parveen Bansal
pp. 389–391 · DOI: 10.5530/jyp.2020.12.99 · Published
Background:Roscoea purpurea also known as Kakoli is an endangered species of “Ashtawarga” group which faces immense identification and authentication crisis in Ayurvedic literature. Due to less availability and high medi…