Volume 14, Issue 3

· pp. 266–346 · 17 articles

Volume: 14
Issue: 3
Published
Pages: 266–346
Articles: 17
Sections: 4
ISSN: Print - 0975-1483 | Online - 0975-1505
Journal: JYP

Editorial Review Article Original Artcile Case Report

In this issue

Editorial

Forum Article
Repurposing of Drugs for Non-responding Erythema Nodosum Leprosum Cases - A Perspective
Pugazhenthan Thangaraju, Sree Sudha TY, Sajitha Venkatesan
pp. 266–267 · DOI: 10.5530/jyp.2022.14.53 · Published
Leprosy (Hansen’s disease) caused by Mycobacterium lepra is a debilitating tropical disease having maximal stigma till date. Efforts have been made for many decades to keep disease incidence under control. In 2019, 202,1…

Review Article

Review
Clustered Regularly Interspaced Short Palindromic Repeats and its Associated Protein- 9: Drug Delivery and Therapeutic Applications
Chinthaginjala Haranath, Rachana Jonnala, Eranti Bhargav, Hindustan Abdul Ahad, Pavan Kumar Chintamaneni
pp. 268–272 · DOI: 10.5530/jyp.2022.14.54 · Published
Genomic editing, which involves modifying genetic DNA at a specific target site, is now being sought by scientists all over the world in a variety of domains. To achieve the desired result, genome editing entails adding,…
Review
Overview of Forced Degradation Analysis for FDA Approved Antiretroviral agents: A Review
Suman Lamichhane, Bhaswati Das, Rudra Prasad Adhikari, Mari Raju Jeyaprakash
pp. 273–282 · DOI: 10.5530/jyp.2022.14.55 · Published
Forced degradation and its analysis play a crucial role in the development and production of pharmaceutical products at various stages. Such studies include the assessment of appropriate drug candidates, product developm…

Original Artcile

Article
Insight and Perspective on Omicron’s Development, Behaviour, and Vaccine Breakthrough: Next Sequelae of COVID-19
Krishna Yadav, Deependra Singh, Manju Rawat Singh, Ajazuddin A, Amit Alexander, Sunita Minz, Madhulika Pradhan, Kamal Shah, Nagendra Singh Chauhan
pp. 283–288 · DOI: 10.5530/jyp.2022.14.56 · Published
Background:The Severe Acute Respiratory Coronavirus (SARS-CoV-2) has emerged in a variety of forms since its first appearance in early December 2019. The Omicron variation (B.1.1.529) was recently confirmed as a relative…
Article
Litsea polyantha Extracts Ameliorate Diabetes and Oxidative Stress in Streptozocin-induced Diabetic Rats
Waseem Khan, Jaya Sharma, Sanjay Singh, Pankaj Sharma
pp. 289–294 · DOI: 10.5530/jyp.2022.14.57 · Published
Objectives:Litsea polyantha (LP) is a traditional medicinal plant in India. As the bark is mildly astringent, it is traditionally used to treat diarrhoea. Powdered bark and roots are used for pain, bruises, contusions, a…
Article
Fabrication and Evaluation of Controlled Release Transdermal Drug Delivery System of Carvedilol using Design Expert® Software for the Management of Hypertension
Saurabh Maan, Roop Krishen Khar, Rupa Mazumder, Nishant Yadav, Urooj Ahmed Khan
pp. 295–301 · DOI: 10.5530/jyp.2022.14.58 · Published
Objectives:Design, development and characterization of controlled release transdermal drug delivery system of carvedilol using Design Expert® software for managing hypertension. Materials and Methods:CV undergoes extensi…
Article
A Study of Diabetic and Non-diabetic Human Cataract Lens by Scanning Electron Microscopy
Swathy Govindaswamy, Dhivya Sundaram
pp. 302–304 · DOI: JYoungPharm-14-3-302 · Published
Background:This research aimed to ascertain the differences in morphological manifestation in the human diabetic cataractous lens compared to a non-diabetic cataractous lens by Scanning Electron Microscopy (SEM). Materia…
Article
A Prospective Study to Estimate the Prevalence of Cognitive Impairment and its Risk Factors in Patients having Diabetes Mellitus or Hypertension or a Combination of Both
Ashish Karn, Nair Jitin Raghunathan, Nathani Anamika, Naik Manmayee Manishbhai, Hemraj Singh Rajput, Vivek Vaswani
pp. 305–309 · DOI: 10.5530/jyp.2022.14.60 · Published
Background:Different studies across the world have shown there is an association between non-communicable diseases (NCDs) and accelerated decline of cognitive function leading to mild cognitive impairment. The aim of the…
Article
Impact of National List of Essential Medicines (NLEM) on Cost Variation of Immunosuppressants available in Indian Market
Prachitee Borkar, Viraj Shinde, Prasan Bhandari, Ramanand Patil
pp. 310–313 · DOI: 10.5530/jyp.2022.14.61 · Published
Background: Immunosuppressants are used commonly in two conditions: to prevent graft versus host rejection in transplantation and autoimmune disorders. Autoimmune diseases are chronic in nature requiring lifelong treatme…
Article
A Cross Sectional Observational Study to Assess Clinical Characteristics, Prescription Pattern and Health Related Quality of Life in Migraine Patients at Tertiary Care Teaching Hospital
Rajesh Hadia, Vidhi Kapadi, Kushal Parekh, Sunetra Naidu, Sanjay Prakash, Vikas Chandrakar, Hemraj Singh Rajput
pp. 314–321 · DOI: 10.5530/jyp.2022.14.62 · Published
Objectives: The present study was focused on assessing the clinical characteristics which include the symptom profile, triggering factors, prescription pattern, headache-related disability, and its impact on patients’ HR…
Article
The Association of Medication Complexity with COVID-19 Severity and its Impact on Pharmacotherapy Evaluation
Yogendra Shrestha, Rajesh Venkataraman, Jeet Bahadur Moktan, Sonakshi Mallikarjuna, Sindhu Shree Narayan, Manisha Hemmige Madappa, Priyanka Anekere Satya
pp. 322–326 · DOI: 10.5530/jyp.2022.14.63 · Published
Background:Off-level medicines do not provide adequate health outcomes since there is insufficient efficacy and/or toxicity evidence. Offlevel medicines are more vulnerable to adverse drug reactions (ADRs), which are a p…
Article
The Impact of Theoretical and Practical Guidance Regarding Metered Dose Inhaler Technique on Asthma Patients
Sara Shahid, Fahad Ahmed, Gul Shahnaz, Muhammad Saqlain, Muhammad Ans, Anosh Sana, Abdul Nazer Ali, Ahmad Kamal Ariffin Abdul Jamil, Asma Fareed Khan, Saba Naeem, Shakeel Ahmad, Aiman Mahmood, Qandeel Rafi, Asifa Anwar, Rabeel Khan, Naeem Mubarak
pp. 327–332 · DOI: 10.5530/jyp.2022.14.64 · Published
Background: Asthma is rapidly increasing globally. Inhalation therapy is the backbone for asthma management due to localized delivery and rapid onset of action. Currently, metered dose inhalers (MDIs) are the most widely…
Article
In vitro Evaluation of Antimicrobial Activity of Brazilian Red Propolis Containing-dentifrice
Francineudo Oliveira Chagas, João Hildo de Carvalho Furtado Júnior, Marta Maria de França Fonteles, Renato Daniel de Freitas, Edilson Martins Rodrigues Neto, Emmanuel Arraes de Alencar Júnior, Juliana Araujo Sarmento, Sarah Gabrielle Sousa de Oliveira Rodrigues, Patricia Leal Dantas Lobo, Ana Cristina de Mello Fiallos, Mary Anne Medeiros Bandeira
pp. 333–336 · DOI: 10.5530/jyp.2022.14.65 · Published
Background:This study evaluated the antimicrobial activity of brazilian red propolis (BRP) dentifrice and compare in vitro. Materials and methods: Strains of S. mutans ATCC UA159 were used in the present study. This stud…

Case Report

Article
Cayler Syndrome with Isolated Cleft Palate: Case Report
Elizabeth Jacob, Cyril Sajan
pp. 337–338 · DOI: 10.5530/jyp.2022.14.66 · Published
The present study was focused on assessing the clinical Isolated cleft palate is the term used when a cleft occurs only within the palate. In clinical terms it is differentiated from other clefts, affecting the primary p…
Article
H. pylori and Alcohol-induced Immune Thrombocytopenic Purpura: A Case Report
Hemraj Singh Rajput, Helly Sheth, Vidhi Patel, Anjali Lalani, Harsh Chudasama
pp. 339–341 · DOI: 10.5530/jyp.2022.14.67 · Published
Immune thrombocytopenic purpura is a rare autoimmune disorder. ITP is a multicausal disease that can be mainly caused by infection (H. pylori, viral infection), excessive alcohol consumption, drugs like antibiotics, diur…
Article
Lower Transverse Vaginal Septum with Hematocolpos: A Case Report
Gayathri Kothawar, Harshith Kowtha, Ramya Balaprabha
pp. 342–344 · DOI: 10.5530/jyp.2022.14.68 · Published
Hematocolpos is a medical condition in which the vagina is pooled with menstrual blood. It is caused mainly 4 reasons Imperforated hymen, Cervical atresia, Vaginal atresia and Transverse vaginal septum. Transverse vagina…
Article
NPK Biofertilizer Poisoning and its Management: A Case Report
Sarvajeet Khare, Nishi Sheth, Zeeshan Ali, Naveen Sharma, Jitendra Vaghasiya
pp. 345–346 · DOI: 10.5530/jyp.2022.14.69 · Published
NPK Biofertilizer are used for agricultural purpose to increase the crop yield. If swallowed in small amount they are poisonous and harmful to human health. Containing certain macronutrients such nitrogen, phosphorous an…