GC-MS and Bioactivity of the Essential Oil of Senecio rowleyanus Jacobs
S. S. El Hawary1, A. E. Galal1, M. F. Yousif1★, F. N. Kirollos1★ Corresponding author
- 1Department of Pharmacognosy, College of Pharmacy, Kasr El-Einy Street, 11562, Cairo University, Cairo, Egypt.
CORRESPONDENCE
M. F. Yousif
Yousif M. F.,Department of Pharmacognosy, College of Pharmacy, Kasr El-Einy Street, 11562, Cairo University, Cairo, Egypt.
Volume 4, Issue 16 · pp. 273–274 · PUBLISHED 2008 · DOI:
ABSTRACT
The chemical composition of the essential oil of Senecio rowleyanus Jacobs obtained by hydro distillation was analyzed by GC-MS and tested for cytotoxic and antimicrobial activities. Twenty five components representing 99.95% of the oil composition were identified. The oil was found to contain a significant amount of sesquiterpene alcohols of the guaiane type. Spathulenol (22.9%), germacrene B (12.4%), myrcene (12.8%) and viridiflorol (11%), were the predominant components. The oil exhibited marked cytotoxic activity against certain brain and liver human cell lines in vitro. In addition, it showed noticeable antimicrobial effect against the test microorganisms.
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Hawary, S. S. E., Galal, A. E., Yousif, M. F., & Kirollos, F. N. (2008). GC-MS and Bioactivity of the Essential Oil of Senecio rowleyanus Jacobs. Pharmacognosy Magazine, 4(16), 273–274.