Chemical Composition and Hepato-protective activity of Imperata cylindrica Beauv.
Gamal A. Mohamed1, Ahmed Abdel-Lateff2, Mostafa A. Fouad3, Sabrin R. M. Ibrahim4, Ehab S. Elkhayat4★, Tatsufumi Okino4★ Corresponding author
- 1Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
- 2Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.
- 3Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
- 4Faculty of Environmental Earth Science, Hokkaido University, Sapporo, 060-0810, Japan.
CORRESPONDENCE
Ehab S. Elkhayat
Faculty of Environmental Earth Science, Hokkaido University, Sapporo, 060-0810, Japan.
Received: 10-05-2008; Revised: 07-07-2008; Accepted: 02-08-2008.
Volume 5, Issue 17 · pp. 28–36 · PUBLISHED 2009 · DOI:
ABSTRACT
Phytochemical study of the aerial parts of Imperata cylindrica Beauv. (Graminae), growing in Egypt afforded four methoxylated flavonoids 1-4, β-sitosterol-3-O-β-D-glucopyranosyl-6´-tetradecanoate 5, 3-hydroxy-4-methoxy-benzaldehyde 6, together with daucosterol, β-sitosterol and α-amyrin 7-9. To the best of our knowledge, this is the first isolation of compounds 1-5 from the genus Imperata. A significant hepato-protective activity had been observed upon co-administration of the methanolic extracts of I. cylindrica with CCl4. The structures were determined using spectroscopic data; 1D (1H and 13C), 2D (HSQC, and HMBC) NMR; MS; UV and IR.
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Mohamed, G. A., Abdel-Lateff, A., Fouad, M. A., Ibrahim, S. R. M., Elkhayat, E. S., & Okino, T. (2009). Chemical Composition and Hepato-protective activity of Imperata cylindrica Beauv.. Pharmacognosy Magazine, 5(17), 28–36.