Volume 14, Issue 54

10 April 2018 · pp. 141–274 · 22 articles

Volume: 14
Issue: 54
Published: 10 April 2018
Pages: 141–274
Articles: 22
Sections: 2
ISSN: Print - 0973-1296, Online - 0976-4062
Journal: PM

ORIGINAL ARTICLE Original Article

In this issue

ORIGINAL ARTICLE

Article
Chemical Composition and Cytotoxic Activity of Methanol Extract and its Fractions of Streblus asper Leaves on Human Cancer Cell Lines
Preeti Rawat, Anil Kumar, Tryambak Deo Singh, Mahesh Pal
pp. 141–144 · DOI: 10.4103/pm.pm_391_17 · Published 10 April 2018
Background: Streblus asper, family Moraceae is well‑known important medicinal plant used in the Indian system of medicine. In Ayurveda, stem bark of S. asper is recommended against elephantiasis for which there is still …
Article
The Effects of Hesperidin and Quercetin on Serum Tumor Necrosis Factor‑Alpha and Interleukin‑6 Levels in Streptozotocin‑induced Diabetes Model
Eda Dokumacioglu, Hatice Iskender, Tugba Sen, Imran Ince, Ali Dokumacioglu, Yalcin Kanbay, Elif Erbas, Sinan Saral
pp. 167–73 · DOI: 10.4103/pm.pm_41_17 · Published 10 April 2018
Background: Diabetes mellitus (DM) is a metabolic disorder that occurs as a result of absolute or relative insufficiency of insulin release and/or insulin effect due to impairment of carbohydrate, fat and protein metabol…
Article
Hepatoprotective Evaluation of Trapa natans against Drug‑induced Hepatotoxicity of Antitubercular Agents in Rats
Talib Hussain, Gehad M. Subaiea, Hina Firdous
pp. 180–5 · DOI: 10.4103/pm.pm_237_17 · Published 10 April 2018
Background: Medicinal herbs are significantly effective against a variety of liver disorders and Trapa natans was traditionally used for the treatment of anti‑inflammatory, pain disorder, and various types of hepatic ail…
Article
Biochemical Evidence for the Antitumor Potential of Garcinia mangostana Linn. On Diethylnitrosamine-Induced Hepatic Carcinoma
V. Vishnu Priya, Mallika Jainu, Surapaneni Krishna Mohan
pp. 186–90 · DOI: 10.4103/pm.pm_213_17 · Published 10 April 2018
Background: Garcinia mangostana is extensively used in most of the Indian herbal pharmaceuticals and nutraceuticals. Objective: The objective of this study was to elucidate the underlying biochemical protective mechanism…
Article
Total Phenolics, Total Flavonoids, Antioxidant Capacities, and Volatile Compounds Gas Chromatography-Mass Spectrometry Profiling of Moringa oleifera Ripe Seed Polar Fractions
Ismail Abiola Adebayo, Hasni Arsad, Mohd Razip Samian
pp. 191–4 · DOI: 10.4103/pm.pm_212_17 · Published 10 April 2018
Background: Academic reports have confirmed Moringa oleifera leaves to possess significant antioxidant capacities; however, such studies are unavailable for its ripe seeds even though they are more desirous for consumpti…
Article
Evidence for the Involvement of COX-2/VEGF and PTEN/PI3K/AKT Pathway the Mechanism of Oroxin B Treated Liver Cancer
Nan-Nan Li, Xian-Sheng Meng, Yong-Rui Bao, Shuai Wang, Tian-Jiao Li
pp. 207–13 · DOI: 10.4103/pm.pm_119_17 · Published 10 April 2018
Background: Oroxin B (OB) is one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent. Recent studies suggest that flavonoids have obvious anti-liver tumors effect, but the precise m…
Article
Comparison of Bran-Processed and Crude Atractylodes Lancea Effects on Spleen Deficiency Syndrome in Rats
Dong-Hua Xue, Yu-Qiang Liu, Qian Cai, Ke Liang, Bing-Yuan Zheng, Fang-Xiao Li, Xue Pang
pp. 214–219 · DOI: 10.4103/pm.pm_126_17 · Published 10 April 2018
Background: The rhizome of Atractylodes lancea (AL) is usually used for the treatment of various diseases such as spleen deficiency syndrome (SDS). Both bran‑processed and crude AL is included in Chinese Pharmacopoeia. T…
Article
Protective Effect of Water Extracted Spirulina maxima on Glutamate-induced Neuronal Cell Death in Mouse Hippocampal HT22 Cell
Hyeon Yong Lee, Ga Hee Ryu, Woon Yong Choi, Woo Seung Yang, Hyeon Woo Lee, Choong Je Ma
pp. 242–7 · DOI: 10.4103/pm.pm_191_17 · Published 10 April 2018
Introduction: Spirulina maxima was used as important nutritional source in the Aztec civilization because it is rich in proteins and vitamins. It contains various antioxidants such as phycocyanin and flavonoids. Based on…

Original Article

Article
Herbal Medicines Showing Synergistic Effects with Tumor Necrosis Factor‑Related Apoptosis‑Inducing Ligand (TRAIL) against A549 TRAIL‑resistant Lung Cancer Cells: A Screening Study
Shuen Cheng Chiang, Yeon‑Jung Choi, Shi‑Eun Kang, Miyong Yun, Beom‑Joon Lee
pp. 145–148 · DOI: 10.4103/pm.pm_270_17 · Published 10 April 2018
Background: Tumor necrosis factor‑related apoptosis‑inducing ligand (TRAIL) is a cytokine that activates apoptosis through death receptors on the cell surface and is regarded as a potential anticancer agent. However, man…
Article
In vitro Induction and Generation of Tetraploid Plants of Sophora tonkinensis Gapnep
Kun Hua Wei, Jian Ping Xu, Lin Xuan Li, Jin Yuan Cai, Jian Hua Miao, Min Hui Li
pp. 149–154 · DOI: 10.4103/pm.pm_170_17 · Published 10 April 2018
Background: Sophora tonkinensis Gapnep. is an important medical plant in China. Early researches of S. tonkinensis were focused on rapid propagation and quality analysis of in vitro tissue culture plantlet, and still no …
Article
Optimization of Extraction Conditions for Phenolic Acids from the Leaves of Melissa officinalis L. Using Response Surface Methodology
Guijae Yoo, Il Kyun Lee, Seonju Park, Nanyoung Kim, Jun Hyung Park, Seung Hyun Kim
pp. 155–161 · DOI: 10.4103/pm.pm_70_17 · Published 10 April 2018
Background: Melissa officinalis L. is a well‑known medicinal plant from the family Lamiaceae, which is distributed throughout Eastern Mediterranean region and Western Asia. Objective: In this study, response surface meth…
Article
Determination of Five Chemical Markers in DF Formula, the Herbal Composition of Ephedra intermedia, Rheum palmatum, and Lithospermum erythrorhizon, Using High‑performance Liquid Chromatography‑ultraviolet Detection
Birang Jeong, Jong Seong Roh, Michung Yoon, Yoosik Yoon, Soon Shik Shin, Hyun Joo Cho, Yong Soo Kwon
pp. 162–166 · DOI: 10.4103/pm.pm_189_17 · Published 10 April 2018
Background: DF formula is a herbal preparation comprised three medicinal herbs, namely, Ephedra intermedia, Rheum palmatum, and Lithospermum erythrorhizon, which is being used for the treatment of obesity and liver fibro…
Article
Anti‑inflammatory Effects of Brassica oleracea Var. capitata L. (Cabbage) Methanol Extract in Mice with Contact Dermatitis
Youjung Lee, Seoyoung Kim, Beodeul Yang, Chiyeon Lim, Jung‑Hoon Kim, Hyungwoo Kim, Suin Cho
pp. 174–179 · DOI: 10.4103/pm.pm_152_17 · Published 10 April 2018
Background: Cabbage, Brassica oleracea var. capitata L., is one of the most common vegetables in the world. Because of its high levels of flavonoids and anthocyanins, cabbage has long been used as a herbal medicine. The …
Article
Study on Extraction and Purification of Apigenin and the Physical and Chemical Properties of Its Complex with Lecithin
Korbanjhon Brad, Yan Zhang
pp. 203–206 · DOI: 10.4103/pm.pm_159_17 · Published 10 April 2018
Background: The apigenin has important medicinal value. However, the low solubility of apigenin in water significantly reduced its application. Objective: In this study, the apigenin was extracted, and the complex of api…
Article
Combination of Garcinia cambogia Extract and Pear Pomace Extract Additively Suppresses Adipogenesis and Enhances Lipolysis in 3T3‑L1 Cells
Kushal Sharma, Siwon Kang, Dalseong Gong, Sung‑Hwa Oh, Eun‑Young Park, Min‑Ho Oak, Eunyoung Yi
pp. 220–226 · DOI: 10.4103/pm.pm_388_17 · Published 10 April 2018
Background: Inhibition of adipogenesis has been a therapeutic target for reducing obesity and obesity‑related disorders such as diabetes, hypertension, atherosclerosis, and cancer. For decades, anti‑adipogenic potential …
Article
Identification of Potential Anticancer Protein Targets in Cytotoxicity Mediated by Tropical Medicinal Fern Extracts
Siok‑Thing Tan, Hean‑Chooi Ong, Tsun‑Thai Chai, Fai‑Chu Wong
pp. 227–230 · DOI: 10.4103/pm.pm_282_17 · Published 10 April 2018
Background: Medicinal fern species represent a potentially important source for both food and medicinal applications. Previously, two underutilized tropical fern species (Blechnum orientale and Phymatopteris triloba) wer…
Article
Ingenine F: A New Cytotoxic Tetrahydro Carboline Alkaloid from the Indonesian Marine Sponge Acanthostrongylophora ingens
Sabrin Ibrahim, Gamal Mohamed, Rwaida Al Haidari, Amal El‑Kholy, Mohamed Zayed
pp. 231–234 · DOI: 10.4103/pm.pm_489_17 · Published 10 April 2018
Background: Marine organisms are established to be a wealthy source of bioactive compounds with diverse chemical structures and bioactivities. Acanthostrongylophora ingens is known to be rich with pyrimidine b-carboline …
Article
Optimal Processing Conditions of Boswellia carteri Birdw. Using Response Surface Methodology
Jee–Hyun Yoon, Jung–Hoon Kim, Seong–Sik Ham, Bu–Yeon Gang, Seung–Ho Lee, Goya Choi, Young–Sik Kim, Guemsan Lee, Young–Sung Ju
pp. 235–241 · DOI: 10.4103/pm.pm_140_17 · Published 10 April 2018
Background: Boswellia carteri Bridw. is being widely used for its anti‑inflammatory properties, as well as for wound healing, antimicrobial, and immunomodulatory properties, and boswellic acids (BAs) are considered to be…
Article
Rapid Screening and Characterization of Acetylcholinesterase Inhibitors from Yinhuang Oral Liquid Using Ultrafiltration‑liquid Chromatography‑electrospray Ionization Tandem Mass Spectrometry
Haomin Zhang, Yinan Guo, Lingwen Meng, Hui Sun, Yinping Yang, Ying Gao, Jiaming Sun
pp. 248–252 · DOI: 10.4103/pm.pm_166_17 · Published 10 April 2018
Background: At present, approximately 17–25 million people in the world suffer from Alzheimer’s disease (AD). The most efficacious and acceptable therapeutic drug clinically are the acetylcholinesterase inhibitors (AChEI…
Article
A Novel Method to Mask the Bitter Taste of Berberine Hydrochloride: Powder Surface Modification
Hong Jiang, Dingkun Zhang, Jing He, Xue Han, Junzhi Lin, Yang Lan, Xi Xiong, Lingying Yu, Ming Yang, Li Han
pp. 253–260 · DOI: 10.4103/pm.pm_114_17 · Published 10 April 2018
Background: Berberine hydrochloride (BH) is widely used as a nonprescription drug to treat diarrhea without drug resistance and side effects worldwide. However, its drastic bitterness affects patient compliance severely.…
Article
In vitro Antioxidant Potentials of Cyperus rotundus L. Rhizome Extracts and Their Phytochemical Analysis
Arunagiri Kamala, Sushil Kumar Middha, Chitra Gopinath, H. S. Sindhura, Chandrakant S. Karigar
pp. 261–267 · DOI: 10.4103/pm.pm_228_17 · Published 10 April 2018
Background: Cyperus rotundus L. (family Cyperaceae), native to India, is a multivalent medicinal plant widely used in conventional medicine. The research reports on bioactive components from C. rotundus L. are scanty. Ob…
Article
Modulatory Effect of Carotenoid Supplement Constituting Lutein and Zeaxanthin (10:1) on Anti-oxidant Enzymes and Macular Pigments Level in Rats
Jayashree Madhavan, Sundaram Chandrasekharan, Priya MK, Ashok Godavarthi
pp. 268–274 · DOI: 10.4103/pm.pm_340_17 · Published 10 April 2018
Background: Human eye is constantly exposed to different wavelengths and intensities of light. Oxidative stress results in distinct changes to retinal organs and tissues. Macular pigments (lutein and zeaxanthin), present…