Comparative Study of Cuscuta reflexa and Cassytha filiformis for Diuretic Activity
Sharma Sakshy2, K.K Hullatti2★, S.M. Prasanna2, I.J Kuppast2, Sharma Paras2★ Corresponding author
- 1Department of Pharmacognosy, National College of Pharmacy, Shimoga-INDIA
- 2Department of Pharmacology, National College of Pharmacy, Shimoga-INDIA
CORRESPONDENCE
K.K Hullatti
Akkiraju SudheerDepartment of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Chiyyedu, Anantapuram, Andhra Pradesh, INDIA.
Received: 25-11-2009; Revised: 25-08-2009; Accepted: 25-08-2009.
Volume 1, Issue 5 · pp. 327–330 · PUBLISHED Sep-Oct 2009 · DOI:
ABSTRACT
Aqueous and alcoholic extract of Cuscuta reflexa and Cassytha filiformis were investigated for diuretic activity in Wister rats. The extracts were administered once orally at a dose of 300mg/kg. Frusemide (20mg/kg) was used as standard reference drug and normal saline (25 ml/kg) was used as control. Total urine volume and concentration of Na+, K+ and Cl− excreted in urine were estimated. Aqueous and alcoholic extract of Cuscuta reflexa and Cassytha filiformis exhibited significant diuretic activity and caused marked increase in Na+ and K+ excretion, when compared to saline treated controls. However the diuretic activity of Cassytha filiformis extract was higher than that of Cuscuta reflexa.
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Sakshy, S., Hullatti, K., Prasanna, S., Kuppast, I., & Paras, S. (2009). Comparative Study of Cuscuta reflexa and Cassytha filiformis for Diuretic Activity. Pharmacognosy Research, 1(5), 327–330.