jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Pharmacognosy ResearchNOW IN
Article

Phytochemical and Pharmacological Screening of Begonia grandis Dryand

Srinivasarao Pendy1, Krishna Nallamothu1, Ganapaty Seru2★, Sunitha Katta2, Sumanta Mondal2★ Corresponding author

  1. 1Research and Development Wing, Divis Laboratories Ltd, Visakhapatnam, Andhra Pradesh, INDIA.
  2. 2GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.

CORRESPONDENCE

Ganapaty Seru

GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA.

ganapatyseru@gmail.com

Received: 08-07-2020; Revised: 15-07-2020; Accepted: 15-09-2020.

Volume 12, Issue 4 · pp. 375–379 · PUBLISHED · DOI: 10.4103/pr.pr_67_20

View on PR original site ↗

ABSTRACT

Begonia grandis Dryand (Family: Begoniaceae) was screened for its phytoconstituents and evaluated for its ethnomedicinal potential as an antioxidant and hepatoprotective agent. The preliminary phytochemical studies of the B. grandis revealed the presence of alkaloids, flavonoids, glycosides, triterpenoids, and steroids. Antioxidant effect of the methanolic extract was assessed by DPPH, superoxide, hydroxyl radical scavenging activity, and hepatoprotective effect by CCl4-induced hepatotoxicity. The extract showed significant antioxidant and hepatoprotective effects at a dose of 400 mg/kg similar to that observed in ascorbic acid and silymarin.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Pendy, S., Nallamothu, K., Seru, G., Katta, S., & Mondal, S. (). Phytochemical and Pharmacological Screening of Begonia grandis Dryand. Pharmacognosy Research, 12(4), 375–379. https://doi.org/10.4103/pr.pr_67_20