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Review

The Ocean's Treasure Trove: Bioactive Compounds from Sea Sponges

Sheetal Sadguru Samant1★, Anvay Ashok Satpute1, Mikhil Prasad Mayekar1, Shamita Shamsundar Loke1, Shweta Nitin Bhatkar1, Mohammad Saad Golandaj1, Tanvi Deepak Rawool1, Vijay Arjun Jagtap1★ Corresponding author

  1. 1Department of Pharmacognosy and Phytochemistry, Yashwantrao Bhonsale College of Pharmacy, University of Mumbai, Sawantwadi, Maharashtra, INDIA.

CORRESPONDENCE

Sheetal Sadguru Samant

Assistant Professor, Department of Pharmacognosy and Phytochemistry, Yashwantrao Bhonsale College of Pharmacy, University of Mumbai, Sawantwadi, Maharashtra, INDIA.

sheetal.samant99@gmail.com

ORCID: 0000-0002-6681-9292

Received: 15-01-2025; Revised: 07-02-2; Accepted: 03-03-2025.

Volume 17, Issue 2 · pp. 452–461 · PUBLISHED 2025 · DOI: 10.5530/pres.20252085

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ABSTRACT

Sea sponges are among the oldest living creatures on Earth that have evolved complex chemical defenses to thrive in the ocean's competitive environment. These marine animals have developed an impressive array of bioactive compounds with therapeutic applications. This article explores bioactive compounds derived from sea sponges, showcasing their remarkable therapeutic potential. The article begins by introducing the fascinating world of sea sponges, highlighting their unique biology and ecology. We then delve into the various bioactive compounds isolated from sea sponges. The review highlights the anticancer properties of sea sponge-derived compounds demonstrating their potential in cancer treatment. We also explore their antimicrobial and anti-inflammatory activities, showcasing their potential in combating infectious diseases and inflammatory disorders. The article further discusses the challenges and opportunities in harnessing the bioactive potential of sea sponges. This review serves as a comprehensive resource for researchers, scientists, and students interested in marine biomedicine and natural product drug discovery.

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    Samant, S. S., Satpute, A. A., Mayekar, M. P., Loke, S. S., Bhatkar, S. N., Golandaj, M. S., Rawool, T. D., & Jagtap, V. A. (2025). The Ocean's Treasure Trove: Bioactive Compounds from Sea Sponges. Pharmacognosy Research, 17(2), 452–461. https://doi.org/10.5530/pres.20252085