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New triterpenoid acyl derivatives and biological study of Manilkara zapota (L.) Van Royen fruits

Nesrin M. Fayek1, Azza R. Abdel Monem1★, Mohamed Y. Mossa1, Meselhy R. Meselhy1★ Corresponding author

  1. 1Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt

CORRESPONDENCE

Azza R. Abdel Monem

*Address for correspondence: Dr. Azza R. Abdel Monem, Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.

azzaramy@yahoo.com

Revised: 24-07-2012.

Volume 5, Issue 2 · pp. 55–59 · PUBLISHED January-March 2013 · DOI: 10.4103/0974-8490.110505

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ABSTRACT

b-amyrin-3-(3'-dimethyl) butyrate, a new natural compound was isolated from the fruits of Manilkara zapota (L.) Van Royen, in addition to lupeol-3-acetate and 4-caffeoylquinic acid (cryptochlorogenic acid). The structures of these compounds were identified using different spectral methods (IR, MS, UV, 1H-NMR, 13C-NMR and 2D-NMR). The alcoholic and aqueous extracts of the unripe fruits, in addition to their aqueous homogenate exhibited antioxidant, antihyperglycemic and hypocholesterolemic activities.

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    Fayek, N. M., Monem, A. R. A., Mossa, M. Y., & Meselhy, M. R. (2013). New triterpenoid acyl derivatives and biological study of Manilkara zapota (L.) Van Royen fruits. Pharmacognosy Research, 5(2), 55–59. https://doi.org/10.4103/0974-8490.110505