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Pharmacognosy MagazineNOW IN
Article

Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract

1, 1★, 1, 1, 2, 2, 1, 1★ Corresponding author

  1. 1Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.
  2. 2National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

CORRESPONDENCE

Shuangshuang Qin

Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.

qin_double@126.com

Received: 19-06-2018; Revised: 11-07-2018; Accepted: 15-11-2018.

Volume 15, Issue 60 · pp. 18–23 · 2019 · DOI: 10.4103/pm.pm_317_18

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ABSTRACT

Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> (CQ) is a well-known medicinal plant used in traditional medicine for bone healing.Objective: The present study was aimed to evaluate the anti-inflammatory and antioxidant activities of the methanolic extract of <em>Cissus quadrangularis</em> stem (MECQ).Materials and Methods: The anti-inflammatory activity was evaluated using the carrageenan-induced rat paw edema model. The antioxidant activity was assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay, and total phenolic content (TPC) determination.Results: MECQ showed significant anti-inflammatory activity in a dose-dependent manner. It also exhibited potent antioxidant activity with high TPC.Conclusion: The results suggest that MECQ possesses significant anti-inflammatory and antioxidant activities, which may be attributed to the presence of phenolic compounds.

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    Chen, X., Qin, S., Li, C., Wu, Q., Jiang, C., Yang, J., Guo, X., & Ou, C. (2019). Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract. Pharmacognosy Magazine, 15(60), 18–23. https://doi.org/10.4103/pm.pm_317_18