Volume 17, Issue 75

Ampa Konsue, Teeraporn Katisart

pp. 545–551 · DOI: 10.4103/pm.pm_92_21 · 2021

Objectives: The present study was aimed to evaluate the acute toxicity of O. indicum fruit extracts in male and female rats. Materials and Methods: The acute toxicity study was performed according to OECD guideline. The …

Rongrong Huang, Songxia Lu

pp. 552–557 · DOI: 10.4103/pm.pm_249_20 · 2021

Background: The deposition of amyloid β (Aβ) proteins and hyperphosphorylation of tau proteins are the two notable features of Alzheimer’s disease. During the past decades, novel drug candidates have been found from natu…

Xiao Huang, Pengtao You, Yulin Chen, Tian Zhang, Ling Gong, Pencheng Zou, Weisong Li, Lei Wang, Yanwen Liu, Kun Yu, Bisheng Huang

pp. 558–564 · DOI: 10.4103/pm.pm_427_20 · 2021

Objectives: This study was intended to characterize the morphology and structure of trichomes and the profile of their secretory materials. Materials and Methods: To characterize the morphology and structure of trichomes…

Pei‑Yuan Dou, Lian‑Lian Zhu, Bin Li, Xia Liu, Makhotso Rose Lekhooa, De‑Qiang Dou, Muhammad Riaz

pp. 565–577 · DOI: 10.4103/pm.pm_97_21 · 2021

Aim: To investigate the effect of Atractylodis macrocephalae Rhizoma (AMR) and its effective constituents to alleviate the Rhubarb’s side effect in their pair medicine. Materials and Methods: The mice were administered R…

Zhizheng Zhuang, Jingxuan Wang, Yingshun Yang, Yujiao Hou, Song Li, Yifan Wang, Yan Hu, Fan Wu

pp. 578–586 · DOI: 10.4103/pm.pm_482_19 · 2021

Background: In this study, we investigated the chemopreventive efficacy of fucoxanthin (Fx) on 7,12‑dimethylbenz[a]anthracene (DMBA)‑induced oral cancer in hamsters. Materials and Methods: Twenty‑four male Syrian golden …

Zhen‑Tian Cheng, Xiang‑Ping Yuan

pp. 587–593 · DOI: 10.4103/pm.pm_137_20 · 2021

Objectives: The primary goal of this study was to elucidate the effects and mechanisms of aloperine (Alo) in the renal fibrosis mice with unilateral ureteral obstruction (UUO). Materials and Methods: C57BL/6 mice were ra…

Feyisara Banji Adaramola, Roger Murugas Cooposamy, Olufunmiso Olusola Olajuyigbe

pp. 594–604 · DOI: 10.4103/pm.pm_66_20 · 2021

Objectives: In this study, the functional groups and bioactive compounds in aqueous methanol extract of P. longifolia leaves and its antimicrobial potential were investigated. Materials and Methods: Bioactive constituent…

Min Liu, Chengquan Wen, Shengqi Pan

pp. 605–614 · DOI: 10.4103/pm.pm_313_19 · 2021

Background: Newly, chemopreventive technique might be a hopeful advancement in developing countries for treating cancers with the aid of toxic less natural‑based constituents. Malignancy urges to augment effectual chemop…

Rui He, Sihui Wang, Qing Liu, Kaili Xie, Yongsong Xu, Jinli Shi, Zhimin Wang, Muxin Gong

pp. 615–622 · DOI: 10.4103/pm.pm_47_21 · 2021

Objectives: In this study, we aimed to determine the interaction of paeoniflorin and liquiritin during intestinal absorption. Materials and Methods: The interaction between paeoniflorin and liquiritin (100 μM) was studie…

Cong Xu, Fei Liu, Yu Yang, Feng Yuan, Bo Zhou, Yadong Liu

pp. 623–629 · DOI: 10.4103/pm.pm_339_20 · 2021

Background: Osteoporosis is a serious health problem, especially in the geriatric populations. World widely, it exaggerated the 8.9 million people every year roughly. In the current analysis, we assessed the antiosteopor…

Ning Yi Yap, Sheela Packiaraj David, Huang Fang Zheng, Quan Ming Tan, Leona Yan Peng Quek, Tze Kiat Tan, Han Kiat Ho, Alexandre Chan

pp. 630–635 · DOI: 10.4103/pm.pm_522_20 · 2021

Objectives: In this study, the in vitro inhibition of cytochrome P450 3A4 (CYP3A4) and cytochrome P450 2D6 (CYP2D6) activities, along with the in vitro liver cell toxicity were evaluated for XBYRT and the individual herb…

Suhaina Supian, Machap Chandradevan, Muhamad Aizuddin Ahmad, Lina Rozano, Mohd Shukri Mat Ali

pp. 636–642 · DOI: 10.4103/pm.pm_113_21 · 2021

Objectives: To evaluate the inhibitory activity of Lepisanthes fruticosa pulp extract against NS2B‑NS3 proteases from DENV2 and WNV and identify the metabolites from this fruit extract. Materials and Methods: In vitro DE…

Guorong Zhang, Xinghua Ni, Yizhong Zhou

pp. 643–648 · DOI: 10.4103/pm.pm_565_20 · 2021

Objective: Herein, we investigated the cardioprotective effect of plumbagin in isoprenaline hydrochloride (ISO)‑induced inflammatory response and increase in antioxidant enzymes and Na+/K+‑ATPase activity in MI rats. Mat…

Jianying Zhou, Guoping Jiang, Qin Zhu, Xiaoyan Zhang, Shan Xu, Weiguang Wang, Lun Zhang, Caijuan Si

pp. 649–655 · DOI: 10.4103/pm.pm_475_20 · 2021

Objective: Pachyman might reduce the intestinal dysfunction and inflammation. Therefore, in this study, we aimed to explore the effect of pachymic acid on repairing the intestine mucosal injury in mice. Materials and Met…

pp. 656–656 · DOI: 10.4103/0973-1296.330202 · 2018