Volume 18, Issue 77

John Doe, Jane Smith

pp. 1–5 · DOI: 10.4103/pm.pm_123_22 · 2022

Background: The genus <em>Cissus</em> (Vitaceae) is a rich source of bioactive compounds with diverse pharmacological activities. Objective: This study aimed to evaluate the phytochemical profile, antioxidant, and anti-i…

Bonian Liao, Fangli Luo, Shu Zhang, Zhengwan Deng, Lin Cai

pp. 4–9 · DOI: 10.4103/pm.pm_147_21 · 2022

Objectives: To inspect RR leaves extracts pro‑apoptotic activities on SMMC‑7721 liver cancer cell lines. Materials and Methods: Anti‑cancer effect of RR extracts in SMMC‑7721 liver cancer cell lines was aged rate of cell…

Rustam Ekbbal, Ashif Iqubal, Mohd Asif Ansari, Sayeed Ahmad, Syed Ehtaishamul Haque

pp. 10–21 · DOI: 10.4103/pm.pm_500_20 · 2022

Objectives: In the present study, we explored the cardioprotective effect of swerchirin (SW) extracted from Swertia chirayita in the ISO model. Materials and Methods: SW was isolated from S. chirayita, characterized by h…

Sweta Bhardwaj, Suman Lata, Rajni Garg

pp. 22–28 · DOI: 10.4103/pm.pm_586_20 · 2022

Aim: In the current study, an easy, economical and environmentally friendly one‑pot synthesis technique has been proposed to obtain silver nanoparticles (AgNPs) using Acmella oleracea leaf extract. Materials and Methods:…

Jie Wang, Zhenxing He, Juhua Zhao, Wenming Xiao, Lingling Xiong, Wei Chen

pp. 29–35 · DOI: 10.4103/pm.pm_152_21 · 2022

Objectives: The main intention of these hypothesis anticancer effects of brucine on 7,12‑dimethylbenz(a)anthracene (DMBA)‑induced skin cancer in mouse model through phosphatidylinositol 3‑kinase/protein kinase B (PI3K/AK…

Jing Xie, Xiao-Bo Li, Chun-Hua Ma, Wei-Wei Jiang

pp. 36–43 · DOI: 10.4103/pm.pm_253_21 · 2022

Background: The roots of Panax vietnamensis Ha et Grushv. (PV) are used in the preparation of local drugs to treat cardiovascular and cerebrovascular diseases. However, it is still not clear if the saponins extracted fro…

Yijun Fan, Xueyan Tan, Juan Zhao, Kaigang Yang, Shengdi Wu, Jiao Zhang, Shangrao Pu, Gang Wang, Aoxue Luo

pp. 44–51 · DOI: 10.4103/pm.pm_580_20 · 2022

Aim: We aimed to monitor an acid polysaccharide with antioxidant activity. Materials and Methods: Three acidic polysaccharides (DAP‑A40, DAP‑A60, and DAP‑A80) were extracted from D. aurantiacum imbricate by alkaline aque…

Abdul Haye, Mohd Asif Ansari, Abhinav Saini, Zubair Ahmed, Kavita Munjal, Yasmeen Shamsi, Manju Sharma

pp. 52–65 · DOI: 10.4103/pm.pm_318_21 · 2022

Objectives: The purpose of this research was to find out the plausible mechanisms underlying the synergistic effects of PHF in an experimental setting of diabetes mellitus. Materials and Methods: PHF was evaluated for th…

Swapna B, M. Raghavendra Rao, Satvik Kotha, Sagar. S, Ramachandra Siddamsetty Setty

pp. 66–74 · DOI: 10.4103/pm.pm_357_21 · 2022

Aim: Cancer is one of the life‑threatening diseases which cause severe pathological conditions, leading to mortality. The exhaustive data on the vital role of medicinal plants in combating cancer and related diseases are…

Hye‑Won Lim, Yu‑Hua Huang, Minsik Park, Chang‑Jin Lim

pp. 75–81 · DOI: 10.4103/pm.pm_366_21 · 2022

Objectives: This work aimed to primarily assess the skin anti‑aging potential of its aerial parts. Materials and Methods: The dried aerial parts of water dropwort were extracted with water under high pressure and high te…

Guodong Wu, Haimei Hao, Le Chang, Xiaofeng Cao, Dong Zhang

pp. 82–88 · DOI: 10.4103/pm.pm_214_21 · 2022

Objectives: In this study, we aimed to study the effect of total flavonoids extracted from Hippophae rhamnoides L. (TFH) on the activity of five CYP450 enzymes in rats by high‑performance liquid chromatography (HPLC). We…

Nadta Sukkasem, Waranya Chatuphonprasert, Kanokwan Jarukamjorn

pp. 89–93 · DOI: 10.4103/pm.pm_321_21 · 2022

Objectives: This study determined the impacts of hesperidin and myricetin on CYP450 profiles in FLD mice. Materials and Methods: Adult female mice were fed a high fat diet (HFD, 60 kcal % fat of total food) with daily in…

Namrata Singh, Poonam Kushwaha, Amresh Gupta, Akash Ved, Shivam Swarup

pp. 94–102 · DOI: 10.4103/pm.pm_248_21 · 2022

Objectives: In the present study, Sesamol‑loaded SNEDDS were developed, identified, and assessed for the enhancement of its in vitro dissolution rate and anticancer efficacy. Materials and Methods: Based on the solubiliz…

Ke Lv, Meng Jiang

pp. 103–111 · DOI: 10.4103/pm.pm_571_21 · 2022

Objectives: The objective of the study is to evaluate the potential of OPA against Freund complete adjuvant (FCA)‑induced inflammatory pain in experimental arthritic rats. Materials and Methods: FCA was administered in f…

Xiang Ding, Ying Liu, Yiling Hou

pp. 112–120 · DOI: 10.4103/pm.pm_185_21 · 2022

Background: Polysaccharide biology, whose core is the structure, function, and edible value of polysaccharides, is regarded as the last great scientific frontier outside the field of protein and nucleic acid research. Ma…

Jalaja S. Menon, Berin Pathrose, A. C. Asna, Rukam Singh Tomer, B. Dineshkumar

pp. 121–127 · DOI: 10.4103/pm.pm_435_21 · 2022

Background: In Kerala, dry hill agro ecological zone is famous for the commercial cultivation of hill garlic. Vattavada and Kanthalloor panchayaths in Devikulam block of Idukki district, India, are famous for the cultiva…

Hasan Saeed Alamri

pp. 128–132 · DOI: 10.4103/pm.pm_463_21 · 2022

Background: Crataegus aronia L. Syn: Azarolus (C. aronia) is a hawthorn species and a perennial bush native to Mediterranean regions. It is recognized for its high polyphenol content and potent antioxidant effects. Resea…

Weiwei Zhang, Jincheng Duan, Chunyan Ji, Zhengchun He, Guirong Shi, Meixian Guo, Xiaobo Liu

pp. 133–142 · DOI: 10.4103/pm.pm_213_21 · 2022

Objectives: We intended to purify and gauge the anti‑fatigue effects of a polysaccharide isolated from Vicatia thibertica polysaccharide 1 (VTP1). Materials and Methods: First, the exercise fatigue model was recognized i…

Hari Priyaa G, Sunil S More

pp. 143–151 · DOI: 10.4103/pm.pm_436_21 · 2022

Background: Trachyspermum ammi is a common spice with vital medicinal properties used in Ayurveda to treat many ailments. Furthermore, natural Honey is said to have high levels of antioxidants and anti‑inflammatory prope…

Tugba Dogan, Kadir Batcioglu, Elif Kayhan Kustepe, Ayse Burcin Uyumlu, Yakup Yilmaztekin

pp. 152–159 · DOI: 10.4103/pm.pm_516_21 · 2022

Objectives: The aim of this study was to investigate the protective efficacy of LB, in kidney damage caused by acute pancreatitis (AP). Materials and Methods: In the study, we used 36 female Wistar albino rats (12 in eac…