Volume 20, Issue 3

Original Research Article(continued)

1. Article

   Cannabis sativa L. Fixed Oil and its Nanoemulsion: Effect on Diabetes and Dyslipidemia Induced in Rats

   Helison de Oliveira Carvalho, Alicia de Melo Santos, Abrahão Victor Tavares de Lima Teixeira dos Santos, Danna Emanuelle Santos Gonçalves, Karyny Roberta Tavares Picanço, Belmira Silva Faria e Souza, José Carlos Tavares Carvalho

   pp. 908–920 · DOI: 10.1177/09731296241234123 · 2024

   Background: Diabetes Mellitus (DM) is a syndrome that interferes with energy metabolism and is caused by a decrease and dysfunction of insulin, leading to chronic hyperglycemia. DM associated with dyslipidemia is a sever…

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2. Article

   Therapeutic Potential of Rosa canina L. Seed Oil and Metformin: Modulation of Bax/Bcl-2/p53/ Caspase-3 Pathways and Improvement of Biochemical and Oxidative Stress Parameters in Estradiol-induced Polycystic Ovary Syndrome Rat Model

   Hanping Chen, Xinxin Liang

   pp. 921–933 · DOI: 10.1177/09731296241234124 · 2024

   Background: This study investigated the therapeutic effects of Rosa canina L. seed oil (RCSO) on PCOS using an animal model, focusing on evaluating biochemical factors and the Bax/Bcl-2/p53 and Caspase-3 (Cas-3) pathways…

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3. Article

   Protective Effect of Prunella vulgaris L. Whole Plant or Spicas Water Extracts on Hyperthyroidism with Liver-yang Hyperactivity Syndrome

   Shuang Li, Zhiguo Gong, Xiangling Hu, Yufan Li, Chao Yan, Liping Cao, Yuhang Chen

   pp. 934–944 · DOI: 10.1177/09731296241239160 · 2024

   Background: Prunella vulgaris L. (Lamiaceae) is a perennial medicinal plant commonly used to treat thyroid dysfunction, infectious hepatitis, and mastitis in north-east Asia and Europe. In China, there has been a histori…

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4. Article

   Phytochemical and Anti-inflammatory Activities of Oxytropis aciphylla

   Hao Qian, Jiaqiong Liu, Xianqi Meng, Xiaoqin Wang

   pp. 945–955 · DOI: 10.1177/09731296241240236 · 2024

   Background: The objective of this research is to explore the phytochemical constituents and the potential anti-inflammatory properties of the herb Oxytropis aciphylla. Materials and Methods: From the ethyl acetate and n-…

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5. Article

   Effect of Cryptotanshinone on BDNF/TrkB Pathway in Hippocampus of Chronic Stress-induced Depression Rats

   Shaomei Lin, Shuifa Wu, Wanting Liao, Wanqiong Chen, Congyi Cai, Yin Zhang, Mingzhu Chen

   pp. 956–964 · DOI: 10.1177/09731296241236034 · 2024

   Background: Cryptotanshinone (CTS) is a monomer possessing a diverse array of pharmacological properties, primarily derived from Salvia miltiorrhiza. CTS was examined for its impact on rats with depression subjected to c…

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6. Article

   Baicalin Inhibits VSMC Phenotypic Transition and Ameliorates Atherosclerosis via GSK3β- TCF21 Signaling Pathway

   Meng Huo, Jingjing Lin, Qiaoqiao Xu, Haina Zhang, Qizhen Ye

   pp. 965–972 · DOI: 10.1177/09731296241239152 · 2024

   Background: Atherosclerosis (AS) is the pathological basis of acute myocardial infarction, acute stroke, and other acute critical illnesses. Vascular smooth muscle cell (VSMC) phenotypic transformation plays a remarkable…

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7. Article

   Pyrogallol Suppresses the Tumor Progression

   Hao Liu, Yanxiang Chang, Lei Jin

   pp. 973–982 · DOI: 10.1177/09731296241242542 · 2024

   Background: Pyrogallol, a bioactive compound derived from natural sources, is the focus of this study, aiming to investigate its anti-cancer properties against A549 lung cancer cells and uncover the underlying mechanisms…

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8. Article

   Shikonin Attenuate Behavioral Defects, Oxidative Stress, and Neuroinflammation During Aluminum Chloride-induced Alzheimer’s Disease Condition in an in-vivo Experimental Model

   Danni Li, Min Wang

   pp. 983–995 · DOI: 10.1177/09731296241239153 · 2024

   Background: Aluminum chloride (AlCl3) is an environmental neurotoxin that affects cerebral functions and causes health complications. However, the role of AlCl3 in arbitrating glia homeostasis and pathophysiology remains…

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9. Article

   The Vasodilator Effect and Mechanism of 18β-glycyrrhetinic Acid on Isolated Pulmonary Artery Rings in Rats

   Huijuan Yang, Hailong Li, Yuxin Liu, Jinrui Jiang, Mei Hai, Cong Li, Zhiqiang Hu, Ru Zhou

   pp. 996–1004 · DOI: 10.1177/09731296241241115 · 2024

   Background: The purpose of this study was to evaluate the effect of 18β-glycyrrhetinic acid (18β-GA) on isolated rat pulmonary artery vascular rings as well as the mechanism that lies behind the diastolic effects of this…

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10. Article

    The Beneficial Effects of Topical Cream Containing 17% of Herbal Extract on Skin Barrier Function: A Randomized Four-week Trial

    Ji-Hyo Lyu, Soyeon Kim, Kang Kwon, Yongkuk Kim, Chanhun Choi, Hyunwoo Jeong, Hyungwoo Kim

    pp. 1005–1012 · DOI: 10.1177/09731296241243129 · 2024

    Background: Skin moisture management is important for maintaining healthy skin and treating inflammatory skin diseases, and skin barrier function can be assessed by measuring trans-epidermal water loss (TEWL) and skin mo…

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11. Article

    Study on the Mechanism of Anti-atopic Dermatitis by Herba Siegesbeckiae Based on System Pharmacology

    Xiaowei Chen, YingYue Wang, Xin Zhang, Chang Liu, Chunxue You, Yubin Xu

    pp. 1013–1022 · DOI: 10.1177/09731296241242172 · 2024

    Background: Atopic dermatitis (AD) is a common but complex chronic inflammatory skin condition characterised by intense pruritus, severely impacting patients’ quality of life. At present, there is no specific drug for AD…

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12. Article

    Taraxacum officinale Extracts Alleviate Anhedonia and Depression by Inhibiting UPRmt and Mitophagy in the Hippocampi of T2DM Rats

    Meng Wang, Zhen’an Gao, Leilei Ma, Xiuping Wang, Zhaojia Li, Ji’an Li

    pp. · DOI: 10.1177/09731296231226067

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