Volume 20, Issue 4

Han Yu, Zhijun Wang, Gang Zhao

pp. 1031–1047 · DOI: 10.1177/09731296241228361 · 2024

Background: Chronic liver dysfunction (CLD) is a significant global health issue; alcohol use, obesity, drugs, and antibiotic and viral infections contribute to its development. However, changes in gut microbiota composi…

Mohammed Albratty, Maryam Halawi

pp. 1048–1060 · DOI: 10.1177/09731296241247606 · 2024

Background: The simplest form of carbohydrate that the human body can utilize efficiently to fuel various functions in our body is glucose. The food that is consumed by us in any form is acted upon by pancreatic juices, …

Wei Hao, Yuan Gao, Bangwei Cao

pp. 1061–1070 · DOI: 10.1177/09731296241251957 · 2024

Background: The turmeric rhizome yields a medicinal compound called curcumin. Curcumin’s anticancer methods mostly involve blocking cell invasion and proliferation, controlling gene expression, preventing angiogenesis, t…

Runjia Liu, Yanqing Li, Xiaochen Zhang, Kaixuan Tang, Jiatong Li, Tianhe Fang, Xuanhe Tian, Bingbing Han

pp. 1071–1085 · DOI: 10.1177/09731296241235435 · 2024

Ischemic stroke is a kind of sudden vascular disease of the brain brought on by ischemic hypoxic necrosis of the brain tissue which is becoming a significant global source of death and long-term impairment. Present commo…

Li Li, HaiYan Tan, TianLu Su

pp. 1086–1099 · DOI: 10.1177/09731296241244561 · 2024

Background: Chemotherapy drugs damage intestinal cells, weakening the intestinal barrier. This damage results in higher permeability, which enables bacteria and toxins to enter the intestinal tissue. Purpose: This study …

Jiajia Zhu, Jie Liu, Wei Jia, Guoqiang Shao, Haizhu Xu

pp. 1100–1113 · DOI: 10.1177/09731296241242909 · 2024

Background: Today, network pharmacology and molecular docking were utilized for investigation and prediction of possible mechanisms in fields such as pharmacognosy and traditional Chinese medicine formulas when treating …

Chengchen Zhou, Xiaoling Qin, Jingyi Wang, Yongchang Liu

pp. 1114–1127 · DOI: 10.1177/09731296241264620 · 2024

Background and Purpose: We investigated the effectiveness of Vaccinium arctostaphylos L. fruit extract (VAFE) in protecting hepatocytes against N-diethylnitrosamine (DEN)-related hepatocellular carcinoma (HCC) by explori…

Hui Deng, Yarong Li, Shulan Han, Min Lan, Liqin Cui, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Zhong Li

pp. 1128–1140 · DOI: 10.1177/09731296241242862 · 2024

Background: Diabetes mellitus (DM) induces hyperglycemia and oxidative stress in the kidneys and may cause kidney dysfunction. Diabetic nephropathy (DN) is a prolonged problem of DM with limited treatment. Purpose: In th…

Kyong-Lim Kim, Chiyeon Lim, Sehyun Lim, Suin Cho, Kyung-Min Kim

pp. 1141–1153 · DOI: 10.1177/09731296241242211 · 2024

Background: The proportion of dementia patients in Asian countries is rapidly increasing, and because vascular dementia is more common than in the West, it is recognized as important as Alzheimer’s disease. Purpose: The …

Ying Sun, Peng Gao, Xilin Wan, Xinze Liu, Fang Xu, Jiaqi Wang

pp. 1154–1166 · DOI: 10.1177/09731296241253125 · 2024

Background: Gliomas are highly lethal malignancies that develop in the central nervous system. The primary treatment for gliomas involves surgical resection followed by chemoradiotherapy. However, due to the infiltrative…

Jiahua Liu, Qingqing Liu, Xiaoqin Ma, Weiyan Guo, Jie Mi

pp. 1167–1178 · DOI: 10.1177/09731296231223839 · 2024

Background: The herbal Poria cocos-Liquorice drug pair (PLDP) possesses the ability to be a diuretic, stimulating the spleen and benefiting the kidney, which plays an important role in the treatment of Henoch–Schönlein p…

Yanan Qian, Siomui Chong, Qian Chen, Chengliang Yin, Yujing Cao

pp. 1179–1190 · DOI: 10.1177/09731296241228904 · 2024

Background: Bone tissue undergoes continuous remodeling to maintain a steady state of bone equilibrium. During this process, osteoblasts actively stimulate bone formation, while osteoclasts continuously engage in bone re…

Chong-lu Sun, Yu-jiong Zhang, Song-lin Yu, Shi-min Li, Xiao-yu Hu, Jin-long Xu

pp. 1191–1202 · DOI: 10.1177/09731296241242176 · 2024

Background: The effective extractives of Tetrastigma hemsleyanum (T. hemsleyanum) are useful, but this plant was not fully utilized in rural China. In this study, flavonoids from the aerial parts of T. hemsleyanum were e…

Ojaskumar D. Agrawal, Yogesh A. Kulkarni

pp. 1203–1214 · DOI: 10.1177/09731296241238852 · 2024

Background: Plants from the genus “Terminalia” are well known for their various pharmacological and medicinal properties. Terminalia bellirica is considered a vital medicinal plant from the genus Terminalia. It has been …

Meizhi Li, Shiqing Li, Shanshan Jiang, Weihong Li

pp. 1215–1225 · DOI: 10.1177/09731296241247365 · 2024

Background: Diabetes significantly increases morbidity and mortality rates, causing complications such as cardiovascular disease, kidney failure, and blindness. Purpose: The aim of this study was to investigate the hepat…

Wujiang Ren, Xiaoxiao Li, Tingqiao Wang, Yanxia Liu, Xueling Dai, Qing Huo, Shuo Wang, Qiusheng Zheng, Yaxuan Sun

pp. 1226–1236 · DOI: 10.1177/09731296241246632 · 2024

Background: The rationale for the pathogenesis of Alzheimer’s disease (AD) is the production of amyloid-beta (Aβ) and its resultant toxic effects. Purpose: In this work, rats with AD were used as models to assess the mod…

Zhiying Xu, Chengcheng Lin, Jinghui Sun, He Li, Wenyue Zhuang, Jianguang Chen, Chunmei Wang, Haili Wang

pp. 1237–1247 · DOI: 10.1177/09731296241253896 · 2024

Background: Schisandra chinensis is widely applied in the prevention and treatment of asthma in China, but the material basis for the anti-asthmatic effect of S. chinensis is unclear. Our previous studies found that the …

Weigu Ban, Lina Lu, Xiuying Teng, Yiran Zhang, Hui Qi

pp. 1248–1257 · DOI: 10.1177/09731296241251916 · 2024

Background: Parkinson’s disease (PD), the second most prevalent neurological illness, is treated with pharmacologic and nonpharmacologic techniques, including medicinal plants and their extracts. Purpose: We assessed the…

Li Li, Lin Liu, Hong Qin, Ligang Xing

pp. 1258–1267 · DOI: 10.1177/09731296241255436 · 2024

Background: Renal cell carcinoma, the most prominent kind of adult kidney cancer, lacks early warning symptoms, leading to metastases at the time of diagnosis. Renal cell carcinoma begins with N-diethylnitrosamine (DEN) …

Mohammed Sohel Meah, Pharkphoom Panichayupakaranant, Kris John Silvano, Rakhimov Abdurakhim Ramazon Ugli, Min Gab Kim

pp. 1268–1275 · DOI: 10.1177/09731296241262569 · 2024

Background: A green and efficient process, free from toxic solvents, was employed to prepare an α-mangostin-rich extract. Conventional techniques like maceration and heat reflux extraction are recognized for their time-i…