Table of Contents

Manjunatha Pai Chennaithody, Rajesh Kaverikana Shankar

pp. 224–236 · DOI: 10.5530/pres.20260065 · 2026

Depression is a complex psychiatric disorder with significant global impact. While conventional antidepressants remain the mainstay of treatment, their limitations-such as delayed onset, limited efficacy, and adverse eff…

Megha Patel, Dilsar Gohil, Rajesh Hadia, Hemrajsingh Rajput

pp. 237–242 · DOI: 10.5530/pres.20260076 · 2026

Colorectal Cancer (CRC) remains a pressing global health burden, with limitations in current treatments such as chemoresistance, toxicity, and tumour recurrence. Increasing interest in Phyto therapeutics has led to explo…

Li-Li Chen, Min Liu, Tian-Zhen Xie, Wu-Feng Yang, Ming Gong, Yun-Xiu Cheng, Shuang Long Yang, Wei-You Xie, Zhao-Jie Wang

pp. 243–269 · DOI: 10.5530/pres.20260054 · 2026

In the next 25 years, more than 39 million deaths worldwide could be attributed to bacterial resistance to antibiotics. Urgent action is needed to discover new antibacterial compounds. Traditional medicines worldwide hav…

Nishanthi Gunasekar, Swedha Jaganathan, Athirai Pagalavan Muthukumaravel, Buvan Raj Ayyanar, Surya Ramalingam, Hariprasath Pachaiyappan

pp. 270–278 · DOI: 10.5530/pres.20260090 · 2026

Hashimoto Thyroiditis (HT) is one of the chronic autoimmune diseases of the thyroid gland which is characterized by the gradual destruction of the thyroid and the development of hypothyroidism. It occurs mainly in women …

Ishita Debnath, Suman Ghosh, Nirjhar Duttagupta, Sitanshu Mondal, Jitendra Debata, Sumit Nandi, Soumik Bhattacharjee, Rana Dutta, Sajal Kumar Jha, Nabanita Banik, Mithun Bhowmik, Arindam Chatterjee, Sudip Roy, Ayantika Sil, Amites Gangopadhyay, Avijit Ghosh, Samar Patra, Shubhajit Das, Disha Das, Piyush Mahato, Bapan Khan

pp. 279–294 · DOI: 10.5530/pres.20260146 · 2026

Background Marine-derived microbial metabolites have emerged as an underexplored but exceptionally promising source of antiparasitic agents. Over the past two decades, intensive efforts in natural product discovery have …

Shweta Bhandari, Sufiyameezan Khan, Rahul Trivedi, Rajesh Maheshwari, Swetaba Besh, Dilsar Gohil, Ujjval Vagehla

pp. 295–301 · DOI: 10.5530/pres.20260168 · 2026

Hepatotoxicity is basically harm or else weakening of the liver functioning brought on by a variety of substances, including alcohol, medications, endotoxins, and environmental factors. Because of its high blood perfusio…

Varsha Chauhan, Apoorvi Pathak, Shrikrishna Kaneriya, Dileep Kumar Awasthi Pandit, Jamwant Kumar, Srijal Soni, Kashiram Prajapati, Subnesh Kumar JAIN, Prince Sapkota, Shivam Kumar Gupta, Ganesh Jatav, Ashish Tomar

pp. 302–307 · DOI: 10.5530/pres.20260132 · 2026

Cardiovascular Diseases (CVDs) are a leading cause of global morbidity and mortality, necessitating innovative therapeutic approaches. Traditional medicinal systems, particularly Ayurveda, emphasize natural remedies, wit…

Brindha Sundaramoorthy, Erni Bobbili, Divya Kallingil Gopi, Sunil Kumar Koppala Narayana, Aravind Dhanush, Kanagarajan Arumugam, Narayanan Jegathambal Muthu Kumar

pp. 308–323 · DOI: 10.5530/pres.20260010 · 2026

Background Siddha medicine, with its origin in Tamil Nadu, depicts Tamil culture and way of living. The basis of Siddha medicine is the literary works by Siddhars (physicians who practiced Siddha medicine). Such knowledg…

José del Carmen Rejón-Orantes, Miguel Pérez De La Mora, Mareni Guadalupe Sánchez-Najera, Martha Julia Pascacio Pérez, Gerardo Uriel Bautista Trujillo, Minerva Crespo‐Ramírez

pp. 324–329 · DOI: 10.5530/pres.20260093 · 2026

Background Pozol is a non-alcoholic, non-fermented pre-hispanic beverage prepared with nixtamalized maize and cocoa paste, mixed with water. This refreshing drink is nowadays yet highly consumed in some of the Mexican so…

Teasha Chakraborty, Prasenjit Mondal, Suman Acharyya, Saptarshi Samajdar, Mitali Sahoo, Soubhanik Giri, Sumanta Mondal

pp. 330–340 · DOI: 10.5530/pres.20260058 · 2026

Objectives The present study aimed to scientifically validate the traditional use of Adhatoda vasica root for inflammation management by evaluating the anti-inflammatory activity of its aqueous (AQERAV) and Ethanolic (EE…

Chintan Aundhia, Pramojeeta Rana, Jay Mukesh Chudasama, Chitrali Talele, Bhupendra Prajapati, Pranaykumar Shah, Damiki Laloo, Ghanshyam Parmar

pp. 341–352 · DOI: 10.5530/pres.20260092 · 2026

Background Neuropathic pain affects approximately 7-8% of the global population and up to 24% in certain regions of India, posing significant challenges in management due to its complex etiology and severe symptoms. Conv…

Nisha Ramesh Dubashi, Prashant Dodamani, Madan Desai, Neelam Mishra, Ramakrishna, Badarinath Druvarao Kulkarni

pp. 353–358 · DOI: 10.5530/pres.20260111 · 2026

Background One of the major causes of death in women is breast cancer worldwide. There are a lot of shortcomings in the proper diagnosis of breast cancer at early stages in the medical field. Unremitting research is goin…

Cecileya Jasmin Meshak Dhanashekaran, Manasa Prakash, Sathyageetha Ulaganathan, Vinod Prabhu Venugopal, Radhakrishnan Narayanaswamy

pp. 359–372 · DOI: 10.5530/pres.20260129 · 2026

Background Acrylamide, a widespread dietary and industrial contaminant, is a known neurotoxicant that promotes oxidative stress, inflammation, and neurodegeneration. Identifying effective neuroprotective agents is critic…

Divya Khare, N Santhosh, V Sri Venkata Krishnan

pp. 373–385 · DOI: 10.5530/pres.20260113 · 2026

Background Plants have been major component in medicine in all systems of medicine throughout the centuries. Though there are various plants used in different system of medicine, the availability of the original source h…

Shilpa Mandlik, Ambre Vicky Vilas, Vaishnavi Jagtap, Radha Mhapankar, Bipinchandra Khade, Pradnya Khatav, Sharad Pawar, Deepak Kasote, Archana Sharbidre

pp. 386–395 · DOI: 10.5530/pres.20260139 · 2026

Background High-Sugar Diets (HSD) constitute a significant lifestyle concern, contributing to metabolic disorders and accelerated aging. The fruit fly, Drosophila melanogaster, shares significant genetic and metabolic si…

Lingaraj Jayalakshmi, Rajeshkumar Shanmugam, Sulochana Govindharaj

pp. 396–403 · DOI: 10.5530/pres.20260140 · 2026

Background/Objectives Ruta chalepensis is a herb with many health benefits due to the abundance of secondary metabolite compounds, including both terpenoids and nonterpenoids. Comparative information on effects from indi…

Nimisha Jain, Akash Nayaka, Sarah Priyanka, M Madhan

pp. 404–414 · DOI: 10.5530/pres.20260001 · 2026

Background Growing interest in herbal-based cosmetic products has encouraged the use of environmentally friendly nanotechnology for topical skincare applications. Zinc Oxide (ZnO) nanoparticles are widely used in skin fo…

Suman Supreeti, Vartika Srivastava, Chaitali Pattanayak, Sougata Sarkar, Mangala Charan Das

pp. 415–420 · DOI: 10.5530/pres.20260143 · 2026

Background Diabetes mellitus is a chronic metabolic disorder commonly associated with dyslipidemia and progressive renal dysfunction, contributing to long-term complications. Leaves of Aegle marmelos (Bael), a traditiona…

Maharshi Bhatt, Prasanta Das

pp. 421–434 · DOI: 10.5530/pres.20260147 · 2026

Background Medicinal plants and herb treatment have been emerging as a highly recommended method of disease management due to their therapeutic and nutritional properties. Costus igneus, the chosen plant, is commonly kno…

Pavithra Adarsha Bhat, Chandra Madaiah

pp. 435–444 · DOI: 10.5530/pres.20260124 · 2026

Background Thottea siliquosa is an ethnomedicinal plant widely known for its antidiarrheal properties. Objectives We investigated the antibacterial and antioxidant properties of root, stem and leaves extracted using wate…