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Determinants of COVID-19 vaccine acceptance in a high infection-rate country: a cross-sectional study in Russia

Van D. TRAN1, Tatiana V. PAK2, Elena I. GRIBKOVA2, Galina A. GALKINA2, Ekaterina E. LOSKUTOVA2, Valeria V. DOROFEEVA2, Rebecca S. DEWEY3, Kien T. NGUYEN4, Duy T. PHAM5

  1. 1Department of Drug Administration, Faculty of Pharmacy & Department of Traditional Medicine, Faculty of Medicine, Can Tho University of Medicine and Pharmacy. Can Tho, Vietnam.
  2. 2Department of Management and Economics of Pharmacy, Faculty of Medicine, Peoples' Friendship University of Russia (RUDN University). Moscow, Russia.
  3. 3Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham. Nottingham, United Kingdom.
  4. 4Department of Physiology, Faculty of Medicine, Can Tho University of Medicine and Pharmacy. Can Tho, Vietnam.
  5. 5Department of Chemistry, College of Natural Sciences, Can Tho University. Can Tho, Vietnam.

Received: 06-01-2021; Accepted: 21-03-2021.

Volume 19, Issue 1 · pp. 2276 · PUBLISHED 22 March 2021 · DOI: 10.18549/PharmPract.2021.1.2276

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ABSTRACT

Background: COVID-19 vaccine development is proceeding at an unprecedented pace. Once COVID-19 vaccines become widely available, it will be necessary to maximize public vaccine acceptance and coverage. Objective: This research aimed to analyze the predictors of COVID-19 vaccine acceptance in Russia. Methods: A cross-sectional online survey was conducted among Russian adults from September 26th to November 9th, 2020. Predictors of the intent to take up COVID-19 vaccination were explored using logistic regression. Results: Out of 876 participants, 365 (41.7%) would be willing to receive the vaccine if it became available. Acceptance increased for a vaccine with verified safety and effectiveness (63.2%). Intention to receive the COVID-19 vaccine was relatively higher among males (aOR=2.37, 95% CI 1.41-4.00), people with lower monthly income (aOR=2.94, 95%CI 1.32-6.57), and with positive trust in the healthcare system (aOR=2.73, 95% CI 1.76-4.24). The Russian people were more likely to accept the COVID-19 vaccine if they believed that the vaccine reduces the risk of virus infection (aOR=8.80, 95%CI 5.21-14.87) or relieves the complications of the disease (aOR=10.46, 95%CI 6.09-17.96). Other barriers such as being unconcerned about side-effects (aOR=1.65, 95%CI 1.03-2.65) and the effectiveness and safety of the vaccination (aOR=2.55, 95%CI 1.60-4.08), also affected acceptance. Conclusions: The study showed the usefulness of the health belief model constructs in understanding the COVID-19 vaccination acceptance rate in the Russian population. This rate was influenced by sociodemographic and health-related characteristics, and health beliefs. These findings might help guide future efforts for policymakers and stakeholders to improve vaccination rates by enhancing trust in the healthcare system.

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    TRAN, V. D., PAK, T. V., GRIBKOVA, E. I., GALKINA, G. A., LOSKUTOVA, E. E., DOROFEEVA, V. V., DEWEY, R. S., NGUYEN, K. T., & PHAM, D. T. (2021). Determinants of COVID-19 vaccine acceptance in a high infection-rate country: a cross-sectional study in Russia. Pharmacy Practice, 19(1), 2276. https://doi.org/10.18549/PharmPract.2021.1.2276