Human Rhinovirus: Molecular and Clinical Overview
Ahmad R. Alsayed1★, Anas Abed2, Mahmoud J Al Shawabkeh3, Rania Riyad Aldarawish1, Mustafa Al-Shajlawi4, Nour Alabbas1★ Corresponding author
- 1Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman 11937, Jordan.
- 2Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19328, Jordan.
- 3Department of Basic Dental Sciences, Faculty of Dentistry, Applied Science Private University, Amman 11937, Jordan.
- 4Iraq.
CORRESPONDENCE
Ahmad R. Alsayed
Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman 11937, Jordan. , a.alsayed.phd@gmail.com
Received: 09-07-2023; Accepted: 07-08-2023.
Volume 22, Issue 1 · pp. 2925 · PUBLISHED 6 February 2024 · DOI: 10.18549/PharmPract.2024.1.2925
ABSTRACT
Human rhinoviruses (HRVs) are associated with a wide spectrum of clinical manifestations, ranging from mild cold symptoms to more severe respiratory illnesses, significantly burdening global healthcare systems. At the molecular level, HRVs belong to the Picornaviridae family and are classified into three species: HRV-A, HRV-B, and HRV-C. Advances in genomic sequencing and phylogenetic analysis have revealed a remarkable genetic diversity within HRV species, with over 160 serotypes identified. This genetic variability contributes to the ability of HRVs to evade host immune responses and facilitates their continuous circulation in the population. This review provides an overview of the molecular and clinical aspects of HRV infections.
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Alsayed, A. R., Abed, A., Shawabkeh, M. J. A., Aldarawish, R. R., Al-Shajlawi, M., & Alabbas, N. (2024). Human Rhinovirus: Molecular and Clinical Overview. Pharmacy Practice, 22(1), 2925. https://doi.org/10.18549/PharmPract.2024.1.2925