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Bridging the gap: dental interventions for improved glycemic control in diabetic patients: A systematic review of published studies

Aseel Alotaibi2, Ghaida Alqahtani1, Shouq Alqahtani1, Taif Almutairi1, Lama Alruhaimi1, Nusaybah Alsohibani2, Lamis Alshehri1, Danah Bajunayd1, Shaden Alharbi1, Salma Alsahli1, Arwa Alhamed3, Rahaf Abdulaziz4, Nahaia Alnaiem5, Wejdan Alharthi5, Aminah Alanazi6

  1. 1PharmD student, Princess Nourah Bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia.
  2. 2PharmD student, Princess Nourah University, Riyadh, Kingdom of Saudi Arabia.
  3. 3General Dentist, AlFarbi Medical College, Riyadh, Saudi Arabia.
  4. 4College of Medicine and Surgery, King Khalid University, Abha, Saudi Arabia.
  5. 5Dental Department, Second Health Cluster, North Riyadh Dental Complex, Saudi Arabia.
  6. 6Medical Affairs, Riyadh Health Cluster I - Executive Management for Excellence in Community Health - Co-Executive Management for Medical Affairs - Management, Saudi Arabia.

Received: 06-07-2024; Accepted: 13-11-2024.

Volume 23, Issue 2 · pp. 3180 · PUBLISHED Apr-Jun 2025 · DOI: 10.18549/PharmPract.2025.2.3180

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ABSTRACT

Background: Diabetes poses an increased risk for oral health complications like periodontal disease and candidiasis. Proper dental management can help reduce these risks and support medical glycemic control. Methods: A systematic search of 5 databases was conducted from 2013 to 2023. Included studies evaluated interventions or assessed relationships between dental care and diabetes outcomes. Two reviewers independently screened titles/abstracts and full-texts, extracted data, and assessed risk of bias. Results: An initial search found 895 records, of which 48 were duplicates and 79 were excluded after title/abstract screening. 284 studies underwent full-text review, with 145 excluded for not meeting criteria. 10 studies ultimately met all inclusion criteria. Current evidence establishes periodontitis as a risk factor for worsening diabetes and complications. Periodontal therapy helps manage glycemic control and is most effective with intensive follow-up support. Diabetes increases oral candidiasis risk. Maintaining optimal blood glucose levels reduces periodontal disease prevalence. Conclusion: Current evidence indicates periodontal therapy positively impacts glycemic control in diabetics and intensive follow-up may maximize benefits. Diabetes increases susceptibility to oral candidiasis. Curricula changes equip future dentists to coordinate care considering patients' medical needs.

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      Alotaibi, A., Alqahtani, G., Alqahtani, S., Almutairi, T., Alruhaimi, L., Alsohibani, N., Alshehri, L., Bajunayd, D., Alharbi, S., Alsahli, S., Alhamed, A., Abdulaziz, R., Alnaiem, N., Alharthi, W., & Alanazi, A. (2025). Bridging the gap: dental interventions for improved glycemic control in diabetic patients: A systematic review of published studies. Pharmacy Practice, 23(2), 3180. https://doi.org/10.18549/PharmPract.2025.2.3180