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Review

Pharmacology of Mikania genus: A Systematic Review

Andressa Santa Brigida da Silva1, Alex Oselu Owiti2, Wagner Luiz Ramos Barbosa1

  1. 1Laboratory of Chromatography and Mass Spectrometry, Faculty of Pharmacy, Federal University of Pará, Belém, Pará, BRAZIL.
  2. 2School of Pharmacy, University of Missouri, Kansas City, Missouri, USA.

CORRESPONDENCE

Wagner Luiz Ramos BarbosaLaboratory of Chromatography and Mass Spectrometry, Faculty of Pharmacy, Federal University of Pará, Augusto Corrêa St, 01, CEP 66.075-900- Belém, PA, BRAZIL

barbosa@ufpa.br

Volume 12, Issue 24 · pp. 230–237 · PUBLISHED · DOI: 10.4103/phrev.phrev_10_18

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ABSTRACT

Genus Mikania, in which “guaco” species are included, encloses many species of pharmaceutical interest that are well distributed throughout South America. This work aims to make a systematic review of the clinical and nonclinical data already published about some Mikania species and their existing products, available in the pharmaceutical market. As usual, some species are more studied than others and the most studied species to date are Mikania glomerata, Mikania laevigata, Mikania scandens, and Mikania micrantha. The first two are widely used in Brazil to treat respiratory disorders and are available in different preparations marketed in retail pharmaceutical stores. Among the reported activities, anti‑inflammatory, analgesic, antibacterial, and central nervous system activities were the most tested since they are directly related to the popular use of some species of this genus. In addition, a noteworthy amount of toxicological studies in animals are published in the literature. Thus, this systematic review aims to gather knowledge about Mikania genus and consequently to contribute for a safer use of derivatives of its species.

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    Silva, A. S. B. D., Owiti, A. O., & Barbosa, W. L. R. (). Pharmacology of Mikania genus: A Systematic Review. Pharmacognosy Reviews, 12(24), 230–237. https://doi.org/10.4103/phrev.phrev_10_18