jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Asian Journal of Biological and Life sciencesNOW IN
Article

Preliminary Larvicidal Potential of Andrographis Echioides against Dengue Vector Aedes aegypti Larvae

Singaravel Sengottuvelu1★, Sheik Haja Sherief1, John Staines Mark1, Chinnadurai Kathirvelan2, Banupriya Senthamaraikannan3★ Corresponding author

  1. 1Department of Pharmacology, Nandha College of Pharmacy, Erode, Tamil Nadu, INDIA.
  2. 2Department of Animal Nutrition, Veterinary College and Research Institute, Namakkal, Tamil Nadu, INDIA.
  3. 3Department of Livestock Products Technology – Diary Science, Veterinary College and Research Institute, Namakkal, Tamil Nadu, INDIA.

CORRESPONDENCE

Singaravel Sengottuvelu

Department of Pharmacology, Nandha College of Pharmacy, Erode, Tamil Nadu, INDIA.

sehejan@gmail.com

Received: 24-09-2022; Revised: 13-10-2022; Accepted: 28-10-2022.

Volume 11, Issue 3 · pp. 765–768 · PUBLISHED · DOI: 10.5530/ajbls.2022.11.102

View on AJBLS original site ↗

ABSTRACT

Aim/Background:The present study was conducted to assess the larvicidal potential ofAndrographis echiodiesagainst the dengue vector Aedes aegypti larvae. Alcoholic leaf extract ofAndrographis echiodieswas studied at 500, 250, 125, 62.5, 31.25, and 15.625 ppm concentrations against third-instar larvae of Aedes aegypti.Materials and Methods:100 larvae of Aedes aegypti mosquitoes were exposed to each concentration of both ethanolic and methanolic crude extract ofAndrographis echiodiesin a volume of 100ml. To minimize the error five replicates were employed with respective diluted alcoholic solutions as control. The percentage mortality of larvae at different concentrations of both alcoholic extracts and control were recorded after 24 hr and 48 hr of constant exposure followed by LC50 and LC90 determined.Results:The effective and highest coefficient of determination (R2) was calculated using regression analysis. The effective and highest coefficient of determination (R2) was 0.88 in 24 hr of exposure of larvae in methanolic leaf extract ofAndrographis echioides.Similarly, the effective and highest coefficient of determination (R2) was 0.94 in 24 hr of exposure larvae in ethanolic leaf extract ofAndrographis echioides.Conclusion:From the result it was concluded that both methanolic and ethanolic leaf extract ofAndrographis echioidesexhibited larvicidal activity against the dengue vector Aedes aegypti larvae and it may be due to its secondary metabolite diterpenoid lactone. Further studies may be needed to expose its exact mechanism of action.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Sengottuvelu, S., Sherief, S. H., Mark, J. S., Kathirvelan, C., & Senthamaraikannan, B. (). Preliminary Larvicidal Potential of Andrographis Echioides against Dengue Vector Aedes aegypti Larvae. Asian Journal of Biological and Life sciences, 11(3), 765–768. https://doi.org/10.5530/ajbls.2022.11.102