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Asian Journal of Biological and Life sciencesNOW IN
Article

Evaluating Quality Adjusted Life in Acute Ischemic Stroke Patients: Insights from Door-to-Needle Time Observations

Balaprasath Balaji1★, Aswathee Sivakumar1★, Abin Benny1★, Boobalan Ramalingam1★, Dhanu Veera Pandian2★, Arun Shivaraman3★, Sengottuvelu Singaravel1★, Sheik Haja Sherief1★, Duraisami D1★★ Corresponding author

  1. 1Department of Pharmacy Practice, Nandha College of Pharmacy, Erode, Tamil Nadu, INDIA.
  2. 2Clinical Pharmacist, NG Hospital and Research Centre, Coimbatore, Tamil Nadu, INDIA.
  3. 3Consultant Neurologist, NG Hospital and Research Centre, Coimbatore, Tamil Nadu, INDIA.

CORRESPONDENCE

Balaprasath Balaji

Pharm D, Department of Pharmacy Practice, Nandha College of Pharmacy, Erode-638052, Tamil Nadu, PHILIPPINES.

aswatheesasi@gmail.com

Received: 16-09-2024; Revised: 06-12-2024; Accepted: 24-03-2025.

Volume 14, Issue 1 · pp. 173–176 · PUBLISHED Jan-Apr 2025 · DOI: 10.5530/ajbls.20251362

View on AJBLS original site ↗

ABSTRACT

Aim/Background: To assess the safety and effectiveness of tenecteplase in acute ischemic stroke patients treated within 3.5 hr of symptom on set, evaluating its potential as a cost-effective treatment option. Materials and Methods: Study population: 38 patients over 35 years old, Demographics: Predominantly male (62.5%), age range 56-65 years, Lifestyle analysis: 58.3% smokers, 44.7% alcohol consumers, Treatment: Tenecteplase administered within 3.5 hr of symptom onset. Results: Patient Outcomes: 94.73% achieved independence in daily activities; 56.25% experienced shorter hospital stays (3-5 days); 81.05% positive outcomes at discharge; 94.21% improvement after one month; Quality-Adjusted Life Year (QALY) analysis showed significant improvement; Demonstrated cost-effectiveness compared to other thrombolytic treatments. Conclusion: Tenecteplase emerges as a safe and cost-effective treatment for Acute Ischemic Stroke, demonstrating significant improvements in neurological recovery, patient independence, and potential reduction in healthcare costs while enhancing patient quality of life.

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    Balaji, B., Sivakumar, A., Benny, A., Ramalingam, B., Pandian, D. V., Shivaraman, A., Singaravel, S., Sherief, S. H., & D, D. (2025). Evaluating Quality Adjusted Life in Acute Ischemic Stroke Patients: Insights from Door-to-Needle Time Observations. Asian Journal of Biological and Life sciences, 14(1), 173–176. https://doi.org/10.5530/ajbls.20251362