Volume 14, Issue 1

2025 · pp. 1–221 · 30 articles

Volume: 14
Issue: 1
Published: 2025
Pages: 1–221
Articles: 30
Sections: 3
ISSN: e-ISSN: 2278-5957 | p-ISSN: 2278-747X
Journal: AJBLS

Review Article Research Article

In this issue

Article
In vitro Strategies for the Production of Bioactive Therapeutics from Caralluma Species
Boddupalli Krishna Jaswanth, Pichili Vijaya Bhaskar Reddy, Chadipiralla Kiranmai
pp. 1–7 · DOI: 10.5530/ajbls.20251406 · Published Jan-Apr 2025
<p style="text-align: justify;">Bioactive substances that may be used for therapeutic purposes are key sources of supply from medicinal plants. The conventional techniques used for the extraction of these chemicals somet…

Review Article

Review
Gender Disparities in Cardiovascular Complications of Type 2 Diabetes: Are Females More Frequently in Risk ?
Kissa Zaidi, Divya Kulshrestha, Aakriti Chouhan
pp. 8–17 · DOI: 10.5530/ajbls.20251298 · Published Jan-Apr 2025
<p style="text-align: justify;">Cardiovascular Disease (CVD) continues to be a major cause of death and dejection for people with Type 2 Diabetes Mellitus (T2DM). However, an increasing amount of evidence suggests that t…
Review
The Challenges and Novel Approaches in the Nanoparticle Formulation of DPP Inhibitors
Jaganathan Saravanan, Sundaramoorthi Revathi, Paulraj Ponnaiah, Vitalis Ronald Eden
pp. 18–22 · DOI: 10.5530/ajbls.20251309 · Published Jan-Apr 2025
Drug delivery methods based on nanoparticles have shown great promise in the effective administration of medicinal drugs, such as inhibitors of Dipeptidyl Peptidase (DPP). In the treatment of type 2 diabetes, DPP inhibit…
Review
Scientific Potential of Fish Species Used as Medicine by Indigenous and Non-Indigenous Groups of North East India: A Review with Supporting Research-Based Studies
Tinnu Sonar, Preronaa Gogoi, Bibha Shah, Neha Kumari Prasad
pp. 23–33 · DOI: 10.5530/ajbls.20251314 · Published Jan-Apr 2025
Background: Northeast India is rich in biodiversity, sustaining abundant aquatic fauna. The Indigenous and non-indigenous groups rely on their surrounding biosphere for food and medicines; they use numerous ichthyofauna …
Review
Plant-Based Anti-Inflammatory Agents: A Scientific Review of Bioactive Compounds and Mechanisms
Kavitha Samiappan, Jyothsna Chalakoth
pp. 34–41 · DOI: 10.5530/ajbls.20251437 · Published Jan-Apr 2025
Inflammation, caused by pathogens or damaged tissues, can lead to chronic diseases if left untreated. Although they provide relief, contemporary anti-inflammatory treatments-in particular, non-steroidal anti-inflammatory…

Research Article

Article
On the Occurrence of Cheirotonus gestroi (Scarabaeidae: Coleoptera) in Mizoram, Northeastern India: Molecular and Morphological Characterization
Chawngthu Zothansanga, Tara Malsawmdawngzuali, Betsy Zodinpuii, Lalramliana L
pp. 42–47 · DOI: 10.5530/ajbls.20251747 · Published Jan-Apr 2025
Aim: This study aimed to validate the presence of Cheirotonus gestroi in Mizoram, North-eastern India, expanding its geographical distribution, and providing detailed morphological descriptions, particularly focusing on …
Article
Investigating in vitro Antioxidant and Anti-Inflammatory Activities of Fromia indica Extracts: A Pilot Study
Kavisha Kavindi Perera, Varuni Karunika Gunathilake
pp. 48–55 · DOI: 10.5530/ajbls.20251755 · Published Jan-Apr 2025
Background:Sea Stars are a highly abundant source of bioactive compounds but have been relatively understudied compared to other invertebrates. This study examines anti-inflammatory and antioxidant properties of zoo chem…
Article
Green Synthesis and Comprehensive Characterization of Selenium Nanoparticles: Towards Sustainable Biomedical and Environmental Applications
P. Preethi, A. Antony Annammal, B. Geetha
pp. 56–65 · DOI: 10.5530/ajbls.20251758 · Published Jan-Apr 2025
Background and Rationale: Nanotechnology has revolutionized various scientific disciplines, with Selenium Nanoparticles (SeNPs) demonstrating exceptional potential due to their unique physicochemical properties and appli…
Article
Assessing the Effects of Combined Industrial and Urban Sewage Water on Food Utilization in the Silkworm Bombyx mori L.
Sanjay G B, Asiya Nuzhat F B
pp. 66–70 · DOI: 10.5530/ajbls.20251443 · Published Jan-Apr 2025
Aim/Background:Sericulture is a crucial agro-based sector affected by environmental conditions, especially the quality of mulberry leaves, which serve as the principal food supply for silkworms (Bombyx mori). Materials a…
Article
Isolation of Potential Amylase Producing Bacillus albus and Bacillus paramycoides Bacteria from Sugarcane Bagasse
Muhammad Saeed Khan, Saif Ullah, Faryal Khan, Sundas Mehtab, Waheed Ullah
pp. 71–79 · DOI: 10.5530/ajbls.20251776 · Published Jan-Apr 2025
Background:Enzymes are biological catalysts that play essential roles in metabolic pathways, digestion, energy production, and industrial applications. Amylase, an enzyme that catalyzes the hydrolysis of starch into simp…
Article
LC50 Dependent Safe Concentration of Sodium Arsenate against Crustacean Freshwater Crab, Barytelphusa cunicularis (Westwood in Sykes, 1836)
Aparna Balavant Patil, Nitin Anandrao Kamble
pp. 80–87 · DOI: 10.5530/ajbls.20251381 · Published Jan-Apr 2025
Aim/Background:The study investigates the toxic impact of inorganic arsenic compound (sodium arsenate) on the freshwater crab Barytelphusa cunicularis. Sodium arsenate is a widely used chemical in various applications in…
Article
Amodiaquine as Topoisomerase I Inhibitors: A Computational Approach
Rakki Krishna, Karthikeyan Marimuthu
pp. 88–92 · DOI: 10.5530/ajbls.20251412 · Published Jan-Apr 2025
Aim:The aim of this project is to utilize in silico approaches to identify potential anticancer agents by targeting the human topoisomerase I-DNA complex (PDB ID: 1A35), a critical enzyme involved in DNA replication and …
Article
Consequences of Arsenic Contamination on the Blood Performance and Physiological Status of Anabus testudineus
Wanaz Nasreen Islam, Nasita Rahman
pp. 93–99 · DOI: 10.5530/ajbls.20251421 · Published Jan-Apr 2025
Background: Arsenic (As) is a naturally occurring element found in several water sources, in the form of Arsenate (As (V)) and Arsenite (As (III)). The widespread use of arsenic-based pesticides coupled with industrial a…
Article
Safety Profile of Kumarkalyan Rasa: Subchronic Toxicity Study in Wistar Rats
Shubhangi Pawar, Mahalaxmi Mohan, Uttarksha Ohol, Shishir Pande, Rajshree Kulkarni, Abhay Kulkarni
pp. 100–107 · DOI: 10.5530/ajbls.20251400 · Published Jan-Apr 2025
Kumarkalyan Rasa (KR), a proprietary herbometallic medicine, is used in children to treat a variety of health issues. Because it contains heavy metals, concerns have been raised about the safety of ayurvedic medicines co…
Article
Probiotic Characterisation and Identification of Lactic Acid Bacteria in Panchagavya by 16S rRNA Sequencing
Varsha Muraleedharan, Thamaraiselvi Balasubramanian
pp. 108–118 · DOI: 10.5530/ajbls.20251785 · Published Jan-Apr 2025
Aim:This study focuses on establishing and analyzing the synthesis of Gamma-Aminobutyric Acid using isolates from a synergistic combination, specifically concentrating on fermented panchagavya as a substrate for Lactic A…
Article
Nutritional Comparison of Vegan Yogurts Prepared Using Non-Dairy Lactic Acid Bacteria
Ponnamma Madaiah, Poojitha Kishore, Rakshitha Krishnarajapete Ravi, Swathi Deepak Nayak, Soumya Kallekkattil
pp. 119–126 · DOI: 10.5530/ajbls.20251739 · Published Jan-Apr 2025
Aim: Yogurt is a probiotic-rich fermented dairy product made by lactic acid fermentation using various bacteria. This study explored using chili stalks, a waste product from the chili industry, as a natural starter for f…
Article
Prevalence Trends and Insights of Carbapenem-Resistant Klebsiella pneumoniae Using Diverse Phenotypic Assays
Archana Mani, Anees Pathima, Sasikala Shanmugam
pp. 127–132 · DOI: 10.5530/ajbls.20251417 · Published Jan-Apr 2025
Introduction and Objectives: The emergence and the spread of carbapenem-resistant Klebsiella pneumoniaesignificantly threaten global public health. The detection of carbapenemase is crucial for early targeted therapy and…
Article
Biochemical Analysis and Antimicrobial Activity of Epidermal Mucus of Freshwater Mud Eel Monopterus cuchia
Manash Pratim Sarmah, Bhagyashree Mahanta, Tahsina Shireen, Kamal Choudhury
pp. 133–138 · DOI: 10.5530/ajbls.20251418 · Published Jan-Apr 2025
Background:Among the fishes of North-East India, especially Assam, the Monopterus cuchia is unique for its habitat in the mud. The freshwater mud eel M. cuchia inhabits various shallow, vegetation-rich freshwater environ…
Article
Effect of Agnikarma in the Pain Management of Janu-Sandhigata Vata (Knee-Osteoarthritis) W.S.R to Inflammatory Biomarkers (hs-CRP, TNF-α and IL6)-An Open Labelled Clinical Trial
Himanshi Vats, Pradeep Shahjirao Shindhe, Vijay Kumbar, Ramesh Shivappa Killedar, Rubeen Nadaf
pp. 139–146 · DOI: 10.5530/ajbls.20251410 · Published Jan-Apr 2025
Background:Globally, Osteoarthritis (OA) is the most common cause of disability. The concept that OA is an inflammatory disease has experienced an enormous shift in the last several years. Research indicates that proinfl…
Article
Phytochemical Analysis and Wound Healing Potential of Aloe vera (Aloe massawana) Peel Extract
Princess Jhazzy Panares Arcaya, Laurianne Mae De Claro Capilitan, Zhyanne Rejas Decano, Cathleen Denise Guyo Dugaduga, Aldrich Glenn Lamasan Hernane, Jhovel Roy Dael Calo, Ian Jay Paspe Saldo
pp. 147–152 · DOI: 10.5530/ajbls.20251440 · Published Jan-Apr 2025
Aim/Background:Aloe vera peel extract holds promise for wound healing, yet its specific phytochemical composition and therapeutic potential still need to be explored, especially in San Jose, Malaybalay City, Bukidnon. Th…
Article
Antibacterial Activity and Sensory Profile of Sambong (Blumea balsamifera) Leaf Extract as a Liquid Hand Soap
Sophia Alexa Gamboa Jumalon, Lester William Galacio Capilitan, Xirxes Vhon Dela Cruz Tanquion, Ian Jay Paspe Saldo
pp. 153–160 · DOI: 10.5530/ajbls.20251441 · Published Jan-Apr 2025
Aim/Background:Medicinal plants have long been integral to traditional healing, particularly in Asia. This study investigates the antibacterial efficacy and sensory attributes of Sambong (Blumea balsamifera) liquid hand …
Article
Effect of Bio Formulations on Growth and Yield Parameters of Centella asiatica L., Cultivated in Hydroponic and Field Systems: A Comparative Study
Suheba Belwadi, Adavesh Basavanneppa Holeyache, Sreelekshmi Biju
pp. 161–167 · DOI: 10.5530/ajbls.20251798 · Published Jan-Apr 2025
Background: C. asiatica L is a perennial flowering herb from theApiaceae family having high demand in Ayurvedaand traditional medicine used to treat a variety of health conditions. This study evaluates the effects of bio…
Article
Assessment of Antinutrient Properties of Selected Fruit Peels
Ammabel Oclarit Alza, Romeo Macaltao Del Rosario, Maria Teresa Mabaylan Fajardo
pp. 168–172 · DOI: 10.5530/ajbls.20251208 · Published Jan-Apr 2025
Purpose: The study examined the anti-nutritional composition of four distinct fruit peels and assessed whether these discarded peels retain bioactive substances that have potential health benefits. Materials and Methods:…
Article
Evaluating Quality Adjusted Life in Acute Ischemic Stroke Patients: Insights from Door-to-Needle Time Observations
Balaprasath Balaji, Aswathee Sivakumar, Abin Benny, Boobalan Ramalingam, Dhanu Veera Pandian, Arun Shivaraman, Sengottuvelu Singaravel, Sheik Haja Sherief, Duraisami D
pp. 173–176 · DOI: 10.5530/ajbls.20251362 · Published Jan-Apr 2025
Aim/Background: To assess the safety and effectiveness of tenecteplase in acute ischemic stroke patients treated within 3.5 hr of symptom on set, evaluating its potential as a cost-effective treatment option. Materials a…
Article
Biohydrogen Production through Single Chambered Microbial Electrolysis Cell (MEC)
Shinojus Lovelin Golda Anitus, Anchana Devi Chenniappan, Alison Christina Fernandez, Senthamil Selvi Poongavanam
pp. 177–185 · DOI: 10.5530/ajbls.20251434 · Published Jan-Apr 2025
Biohydrogen production is a promising, clean, and renewable alternative to fossil fuels, and it plays a role in reducing greenhouse gas emissions and promoting energy security. Microbial Electrolysis Cells (MECs) utilize…
Article
Evaluation of Anti-Bacterial and Anti-Biofilm Efficacy of Lygodium flexuosum (L.) Sw.: An in vitro Study
Rejitha Lalitha Rajappan, Chacko Suju Skaria, Amithu Jayakumar Sheeja
pp. 186–191 · DOI: 10.5530/ajbls.20251746 · Published Jan-Apr 2025
Aim: The present study explores preliminary phytochemical analysis, anti-bacterial, and anti-biofilm activities of the leaf methanolic extract of Lygodium flexuosum. Materials and Methods: Soxhlet extraction was done on …
Article
Amylase-Arbitrated Antibiofilm and Anti-Biocorrosion Efficacy of Curcuma zanthorrhiza against Pseudomonas aeruginosa
Delna Joseph, Kayeen Vadakkan, Bince Mani, Meena Kochappan Cheruvathur
pp. 192–197 · DOI: 10.5530/ajbls.20251428 · Published Jan-Apr 2025
Background: The current research explores the antibiofilm and anti-corrosive effects of the hydromethanolic extract of the Curcuma zanthorrhiza rhizome. Biofilm-mediated infections are prevalent and can result in periodo…
Article
Mechanisms of Batch Adsorption of Nickel (II) Ions from Aqueous Solution with Gossypium arboreum Shell Activated Carbon
Saravanakumar Ganesan, Hema Mani, Arivoli Shanmugam
pp. 198–206 · DOI: 10.5530/ajbls.20251390 · Published Jan-Apr 2025
Aim/Background: The effectiveness of an adsorbent made from Gossypium arboreum shell through acid treatment was evaluated in terms of nickel ion removal. Materials and Methods: Process variables that were investigated in…
Article
Muricidae Gastropod Operculum Extract as a Unique Agent against the Osteosarcoma Cell Line: Unveiling its Anti-Angiogenic and Antioxidant Potential
Gurusamy Chelladurai, Petchi Iyappan, Chandramohan Muruganandham, Paulraj Ponnaiah
pp. 207–216 · DOI: 10.5530/ajbls.20251552 · Published Jan-Apr 2025
Aim:India exports the marine Gastropod operculum, which is used in herbal medicine in Indian communities. Background: Because of its usage in traditional medicine, the operculum provides a source of bioactive chemicals. …
Article
Integrative Management of Amavata (Rheumatoid Arthritis): A Case Study Highlighting Ayurvedic Interventions for Detoxification and Digestive Support
Uma Shetti, Jeeru Ojaswini Reddy, Ramesh Shivappa Killedar, Prabhakar Hegade
pp. 217–221 · DOI: 10.5530/ajbls.20251794 · Published Jan-Apr 2025
Background: Rheumatoid Arthritis (RA) is a chronic autoimmune disease-causing joint inflammation, pain, swelling, and stiffness. Conventional treatments, including DMARDs and biologics, often provide incomplete relief, l…