jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Asian Journal of Biological and Life sciencesNOW IN
Review

The Challenges and Novel Approaches in the Nanoparticle Formulation of DPP Inhibitors

Jaganathan Saravanan1★, Sundaramoorthi Revathi1★, Paulraj Ponnaiah2★, Vitalis Ronald Eden3★★ Corresponding author

  1. 1Department of Pharmaceutics, School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry Campus, Puducherry, Tamil Nadu, India.
  2. 2Department of Biotechnology, Faculty of Medicine and Bioscience, MAHSA University, Bandar Saujana Putra, Jenjarom, Selangor Darul Ehsan, Malaysia.
  3. 3Department of Biotechnology, Faculty of Pharmacy, Lincoln University, Petaling Jaya, Sunway City, Malaysia.

CORRESPONDENCE

Jaganathan Saravanan

Dr. Sundaramoorthi RevathiProfessor, Department of Pharmaceutics, School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry Campus, Puducherry, INDIA.

revathis79@gmail.com

Received: 03-01-2025; Revised: 28-01-2025; Accepted: 18-03-2025.

Volume 14, Issue 1 · pp. 18–22 · PUBLISHED Jan-Apr 2025 · DOI: 10.5530/ajbls.20251309

View on AJBLS original site ↗

ABSTRACT

Drug delivery methods based on nanoparticles have shown great promise in the effective administration of medicinal drugs, such as inhibitors of Dipeptidyl Peptidase (DPP). In the treatment of type 2 diabetes, DPP inhibitors are commonly used, and their formulation as nanoparticles offers numerous advantages, such as enhanced bioavailability, controlled release, and targeted delivery. However, several challenges exist in formulating DPP inhibitors into nanoparticles, including drug stability, particle size control, and sustained release kinetics. This review article aims to discuss the challenges associated with nanoparticle formulation of DPP inhibitors and highlight recent innovative approaches to overcome these limitations.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Saravanan, J., Revathi, S., Ponnaiah, P., & Eden, V. R. (2025). The Challenges and Novel Approaches in the Nanoparticle Formulation of DPP Inhibitors. Asian Journal of Biological and Life sciences, 14(1), 18–22. https://doi.org/10.5530/ajbls.20251309