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Asian Journal of Biological and Life sciencesNOW IN
Article

Bioactive Potential of Salicornia europaea Extracts Antioxidant, Anti-Inflammatory, Antivenom, and Anticancer Assay on HepG2 Apoptosis Induction

Malaichamy Manoranjitham1★, Thangam Hemalatha2★, Annamalai Vijayalakshmi3★★ Corresponding author

  1. 1Department of Botany, Thanthai Periyar Government Arts and Science College, Tiruchirappalli, Tamil Nadu, INDIA.
  2. 2Department of Botany, Rani Anna Government College for Women, Tirunelveli, Tamil Nadu, INDIA.
  3. 3Galileovasan Offshore and Research and Development Pvt. Ltd., Nagapattinam, Tamil Nadu, INDIA.

CORRESPONDENCE

Malaichamy Manoranjitham

Associate Professor, PG and Research Department of Botany, Thanthai Periyar Government Arts and Science College, (A), Tiruchirappalli-620 023, INDIA.

drmanoranjithambotany@gmail.com

Received: 18-02-2025; Revised: 07-03-2025; Accepted: 23-06-2025.

Volume 14, Issue 2 · pp. 325–332 · PUBLISHED May-Aug 2025 · DOI: 10.5530/ajbls.20251481

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ABSTRACT

Background: As an ethnomedical herb, Salicornia europaea is widely used in India to cure a variety of illnesses. Objectives: The present studies evaluated an aqueous extract of Salicornia europaea for its anti-inflammatory, antioxidant, anticancer, apoptotic, and anti-venom qualities. Materials and Methods: The DPPH photometric assay, OH radical scavenging capacity, anti-inflammatory activity, Cyclooxygenase (COX), Lipoxygenase (LOX), anticancer, apoptotic, and anti-venom action are a few examples of in vitro models that were used to measure antioxidant activity. Results: The study supported the traditional use of the aforementioned plants in inflammatory disorders by finding that the antioxidant and anti-inflammatory effects of plant extracts may be due to the inhibition of DPPH and OH, COX, and LOX enzymes, respectively. Salicornia europaea's aqueous extract was extremely selective (p<0.005) against HepG2 cells, generating morphological changes, according to the MTT experiment. Conclusion: Because of its strong PLA2 inhibition, the aqueous extract of Salicornia europaea was found to have the strongest and safest anti-inflammatory, antioxidant, anticancer, and anti-venom properties based on the available data.

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    Manoranjitham, M., Hemalatha, T., & Vijayalakshmi, A. (2025). Bioactive Potential of Salicornia europaea Extracts Antioxidant, Anti-Inflammatory, Antivenom, and Anticancer Assay on HepG2 Apoptosis Induction. Asian Journal of Biological and Life sciences, 14(2), 325–332. https://doi.org/10.5530/ajbls.20251481