Identification of Hub Genes and Therapeutic Targets in Lung Cancer Using Software Tools

ABSTRACT

Background: Lung cancer remains a leading cause of cancer deaths. Objective: Identify hub genes associated with lung cancer via GEO curation and PPI/network analyses to prioritize therapeutic targets. Methods: Functional enrichment (DAVID, ShinyGO), druggability assessment (ChEMBL, Pharos). Results: Top hub genes and enriched pathways reported; chemokine receptor activity and T-cell receptor related functions highlighted. Conclusion: Prioritized hub genes provide resources for experimental validation.

KEYWORDS

• Lung Cancer
• Hub genes
• PPI
• Therapeutic targets

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• DOI10.5530/ajbls.20251509Copy

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