Sphaeranthus indicus: A Promising Antimicrobial Agent
Prasoon Kumar Saxena1, Shagun Upadhyay2★, Shivani Lodha3★ Corresponding author
- 1Asst Professor, I.T.S College of Pharmacy, Ghaziabad, Uttar Pradesh, INDIA..
- 2Department of Pharmacy, Government Kalaniketan Polytechnic College, Jabalpur, Madhya Pradesh, INDIA..
- 3Faculty of Pharmacy, Uttarakhand Technical University, Dehradun, Uttarakhand, INDIA..
CORRESPONDENCE
Shagun Upadhyay
Department of Pharmacy, Government Kalaniketan Polytechnic College, Jabalpur, Madhya Pradesh, INDIA..
Received: 27-09-2020; Revised: 21-11-2020; Accepted: 23-12-2020.
Volume 10, Issue 2 · pp. 52–55 · PUBLISHED · DOI: 10.5530/fra.2020.2.10
ABSTRACT
Objectives: The aim of the present study was to determine the antimicrobial property of the solvent extracts of flowers and aerial parts of S. indicus. Methods: The flowers and the aerial parts of Sphaeranthus indicuswere extracted with n-hexane, benzene, chloroform, ethyl acetate and acetone respectively. The extracts were analyzed for the antimicrobial effect by disc diffusion method at concentrations of 5, 2.5 and 1.25 mg/disc. The Minimum Inhibitory Concentration (MIC) was tested using broth micro dilution method at concentrations ranging from 5 to 0.039 mg/ml. Results: There was a significant antibacterial and antifungal activity in hexane extract of flower and aerial parts. The MIC was seen at 0.15 mg/ml against Staphylococcus aureus and the highest MIC (5 mg/ml) was noted for S. epidermidis. The n-hexane extracts of flower and aerial parts showed MIC as 0.15 and 1.25 mg/ml respectively against Candida albicans.Conclusion:Concluding it can be said that the S. indicusflower n-hexane extract showed promising antimicrobial agent.
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Saxena, P. K., Upadhyay, S., & Lodha, S. (). Sphaeranthus indicus: A Promising Antimicrobial Agent. Free Radicals and Antioxidants, 10(2), 52–55. https://doi.org/10.5530/fra.2020.2.10