jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Free Radicals and AntioxidantsNOW IN
Article

Effects of Grape Seed Extract Supplementation and Physical Activity on Skeletal Muscle of Male Albino Rat

Towseef Ahmad Tantry1★, Nazir Ahmad Wani2★ Corresponding author

  1. 1Department of Zoology, Jnanabharathi Campus, Bangalore University, Bengaluru, Karnataka, INDIA..
  2. 2Department of Microbiology and Biotech nology, Jnanabharathi Campus, Bangalore University, Bengaluru, Karnataka, INDIA..

CORRESPONDENCE

Towseef Ahmad Tantry

Department of Zoology, Jnanabharathi Campus, Bangalore University, Bengaluru, Karnataka, INDIA..

tousefzol99@gmail.com

Received: 04-09-2020; Revised: 05-10-2020; Accepted: 21-11-2020.

Volume 10, Issue 2 · pp. 69–76 · PUBLISHED · DOI: 10.5530/fra.2020.2.13

View on FRA original site ↗

ABSTRACT

Objectives:This study investigated the effect of grape seed extract on swim exercise and oxidative stress in acute and chronically exercised rats.Methods: This study was attempted on one month old male albino Wistar rats. Rats were exposed to swim exercise daily for duration of 30 min Day-1. During the experiment estimation of blood parameters, lipid profile, antioxidant enzymes and oxidative stress parameters were evaluated. Results: The endurance capacity was increased by 2.7-fold in the supplemented trainees as compared to the unsupplemented swim trainees which showed an increase by 1.9 fold by the end of 9 weeks compared to the first week. Plasma lactate showed a significant reduction by 25% and 37% in swim trained and supplemented trainees compared to the sedentary. The haemoglobin level showed an increase in the swim trained rats by 19% and 28% in the supplemented trainees compared to the sedentary animals. The packed cell volume increased in swim trained rats by 10% and 19% in the supplemented trainees compared to the sedentary animals. Supplemented trained rats showed a reduction in total cholesterol by 13 % and 15.55% in swim trainees with and without supplementation compared to the sedentary rats respectively. The catalase activity exhibited a significant change in supplemented trainees compared to the sedentary by 20% in Soleus and 71% in extensor digitorum longus compared with the respective sedentary muscle and by 7.5% and 28% compared to the unsupplemented trainees. Conclusion:In conclusion, grape seed extract reduces oxidative stress by increasing antioxidant enzymes activity.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Tantry, T. A., & Wani, N. A. (). Effects of Grape Seed Extract Supplementation and Physical Activity on Skeletal Muscle of Male Albino Rat. Free Radicals and Antioxidants, 10(2), 69–76. https://doi.org/10.5530/fra.2020.2.13