Indian Journal of Pharmaceutical Education and Research
Volume 46, Issue 4
2012 · pp. 296–377 · 11 articles
- Volume
- 46
- Issue
- 4
- Published
- 2012
- Pages
- 296–377
- Articles
- 11
- Sections
- 1
- ISSN
- Online - 0019-5464
- Journal
- IJPER
In this issue
Original Article
- Article
Mudit Dixit, Parthasarthi K Kulkarni, Panner Selvam
pp. 296–302 · 2012
Ketoprofen, an anti-inflammatory drug, exhibits poor water solubility, dissolution and flow properties. Thus, the aim of the present study was to improve the solubility and dissolution rate of Ketoprofen by preparing cry…
- Article
Sushil Kumar, Sushama Talegaonkar, Lalit M. Negi, Zeenat I. Khan
pp. 303–311 · 2012
Onychomycosis is the most common infection of nails caused majorly by Trichophyton rubrum and Trichophyton mentagrophytes and minorly by yeasts. Topical delivery of available ciclopirox formulations as nail lacquer, crea…
- Article
Amit K. Nayak, Dilipkumar Pal, Jyotiprakash Pradhan, Taraknath Ghorai
pp. 312–317 · 2012
The present study deals with the evaluation of mucilage isolated from fenugreek (Trigonella foenum-graecum L.) seeds (commonly named methi) as an innovative and cheap suspending agent. Zinc oxide suspensions (20 % w/v) w…
- Article
R Nagaraju, B Sujatha, S Vidyadhara, RLC Sasidhar
pp. 318–322 · 2012
The present study deals with the formulation of fast dissolving films of nizatidine as a model drug which is used for the treatment of acid-reflux disorders, peptic ulcer disease, and active duodenal ulcer. Rapidly disso…
- Article
A.S Shete, A.V Yadav, M.S Murthy
pp. 323–329 · 2012
The objectives of present investigations were to enhance dissolution rate of irbesartan by using chitosan and chitosan chlorhydrate and optimize an effective concentrations of both. Cocrystals of irbesartan (IB) were pre…
- Article
Vaishali Thakkar, Yasmin Shaikh, Tejal Soni, Tejal Gandhi
pp. 330–339 · 2012
The purpose of present study was to develop once a day sustain release enteric coated tablet of Fluoxetine HCl by direct compression method. Design was prepared for nine batch using fenugreek mucilage at 40%, 50% and 60%…
- Article
Sama Venkatesh, R Kusuma, V Sateesh, B Madhava Reddy, Ramesh Mullangi
pp. 340–345 · 2012
The aqueous ethanolic extract of Pandanus odoratissimus (Pandanaceae) root was tested for its effect on blood glucose levels in normal and diabetic rats. Hypoglycemia was observed in basal conditions when tested at an or…
- Article
Tanushree Singha, Jagadish Singh, Arup Naskar, Tirtha Ghosh, Arijit Mondal, Mrityunjoy Kundu, Ranjit K. Harwansh, Tapan Kumar Maity
pp. 346–351 · 2012
A series of potential bioactive compounds, 4-Amino- 5-mercapto- 3-(4-chlorophenyl)-1, 2, 4-triazole (1d), 4-Amino- 5-mercapto- 3-(4-nitrophenyl)-1, 2, 4- triazole (2d) , 4-Amino- 5-mercapto-3-(2, 4-dichlorophenyl)-1,2, 4…
- Article
Jaynarayan Tripathi, Reena Kumari, Vrish Dhwaj Ashwlayan, Parveen Bansal, Ranjit Singh
pp. 352–359 · 2012
The anti-diabetic activity of methanolic extract of seed of Diplocyclos palmatus Linn. (Cucurbetaceae) was evaluated in streptozotocin-induced diabetic mice. Methanolic extract of the seed (150 mg/kg body weight), was ad…
- Article
N Umarani, K Ilango, P Valentina, T Ishwarya
pp. 366–371 · 2012
In the current investigation, some newer triazines merged benzothiazole hybrids were subjected to molecular properties prediction, drug-likeness, lipophilicity and solubility parameters determination using Molinspiration…
- Article
Mamta Farswan Singh, Vinod Singh, S.P. Rathore, Anupam Bisht, Veerma Ram
pp. 372–377 · 2012
The present study was aimed to evaluate the protective effect of α-tocopherol in simvastatin and gemfibrozil induced rhabdomyolysis in rats. HMG-Coenzyme A reductase inhibitors are the most widely used drug for the treat…