Indian Journal of Pharmaceutical Education and Research
Volume 47, Issue 1
2013 · pp. 1–112 · 16 articles
- Volume
- 47
- Issue
- 1
- Published
- 2013
- Pages
- 1–112
- Articles
- 16
- Sections
- 1
- ISSN
- Online - 0019-5464
- Journal
- IJPER
In this issue
Original Article
- Article
Vanarote D.S, Londhe S.V, Arya. N, Mulgund S.V, Jain K.S
pp. 1–6 · 2013
In drug development, the analytical method development including the bioanalytical method development is essential and useful for the pharmacokinetic study of the lead molecule and is an important step. A sensitive metho…
- Article
Ghanshyam Panjwani, Ragvendra Shetty, Gautham Shenoy, Dinesh Dhamecha
pp. 7–12 · 2013
Ezetimibe belongs to a group of selective and very effective 2-azetidione cholesterol absorption inhibitors that act on the level of cholesterol entry into enterocytes. A new, rapid, specific reversed-phase HPLC method h…
- Article
Shailaja B. Jadhav, Swati K. Kupkar, Deepali L. Dharam, Amol M. Jangam, Praveen D. Chaudhari
pp. 13–16 · 2013
Two simple, specific, accurate and precise methods, namely, reverse phase high performance liquid chromatography and high performance thin layer chromatography were developed for simultaneous estimation of Sitagliptin ph…
- Article
Vaishali Thakkar, Yasmin Shaikh, Tejal Soni, Tejal Gandhi
pp. 17–26 · 2013
The purpose of present study was to develop once a day sustained release enteric coated tablet of Fluoxetine HCl by direct compression method. Design was prepared for nine batch using fenugreek mucilage at 40%, 50% and 6…
- Article
Swapnil T. Deshpande, Swaroop R. Lahoti, Dinesh L.Dhamecha, Vivek B. Rajendra, Mohd. Hassan G.Dehghan, Prashant K. Puranik
pp. 27–33 · 2013
The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Sumatriptan succinate (SS) by iontophoresis. For better bioavailability, better patient compliance, and enhan…
- Article
Shilpa N. Shrotriya, Nisharani S. Ranpise, Shraddha T. Bade, P.D Chudiwal
pp. 34–40 · 2013
The objective of this study was to formulate and optimize taste masked rapidly disintegrating tablet of intensely bitter drug tramadol hydrochloride by 32 factorial design. The drug polymer complex was prepared by coacer…
- Article
Ranpise N.S, Kolhe S.R, Ranade A.N
pp. 41–46 · 2013
Baclofen, related to gamma-amino butyric acid (GABA), blocks the activity of nerves within the part of the brain that controls the contraction and relaxation of skeletal muscle. The oral bioavailability of baclofen is ab…
- Article
Panner Selvam R, Kulkarni P.K, Mudit Dixit
pp. 47–54 · 2013
Efavirenz is an antiretroviral drug which exhibits lower absorption in gastric fluid due to poor water solubility characteristics. Self-nanoemulsifying drug delivery systems (SNEDDS) were designed with the objective of i…
- Article
Valentina Marinković, Elizabeta Kostić, Ljiljana Tasić, Vidosav Majstorović
pp. 55–61 · 2013
Pharmaceutical companies are regularly being challenged to meet the rising standards of quality, so as to comply with rigorous regulatory requirements. At the same time, the global pharmaceutical market has seen signific…
- Article
Development and Evaluation of Novel Mucoadhesive Multipartculate Drug Delivery System of Simvastatin
Naga Phani J.V.V, Mohan Varma M
pp. 62–70 · 2013
The objective of the present study was to prepare the mucoadhesive microspheres of simvastatin to provide oral controlled release.Mucoadhesion had been a topic of interest in the design of drug delivery system to prolong…
- Article
Radhakrishnan Mahesh, Shvetank Bhatt, Thangaraj Devadoss, Ankur Kumar Jindal, Baldev Kumar Gautam, Arghya Kusum Dhar, Dilip Kumar Pandey
pp. 71–81 · 2013
novel 5-HT receptor antagonist '6g' with a good log P and pA value identified from a series of compounds synthesized in our laboratory was subjected to forced 3 2 swim test (FST) (1 and 2 mg/kg, i.p) and tail suspension …
- Article
Vijayalakshmi. A, Ravichandiran. V, Malarkodi Velraj, Nirmala. S, Anusha Male, Jayakumari. S, Masilamani. K
pp. 82–89 · 2013
Objectives: The rhizome of the plant Smilax china Linn. has been used in Siddha and Ayurveda in the treatment of Psoriasis and various skin diseases. In the present study, the methanolic extract and ethyl acetate fractio…
- Article
Nitin. M, Ifthekar. S, Mumtaz. M
pp. 90–96 · 2013
The present study was conducted to investigate the hepatoprotective and nephroprotective activity of methanolic (MEVM) extract of seeds of Vigna mungo (fabaceae) against rifampicin-induced liver and kidney toxicity in ra…
- Article
Arti Jagtap, Manju Bhaskar
pp. 97–102 · 2013
Escitalopram, the S - (+) -enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities. In this present study, antidep…
- Article
Kale M.S, Laddha K.S
pp. 103–105 · 2013
Long chain saturated hydrocarbons were isolated from petroleum ether extract of Momordica tuberosa (Roxb) Cogn. (Cucurbitaceae) fruits. The petroleum ether extract was subjected to silica gel (mesh size 60-120) column ch…
- Article
Sunitha C Srinivas, Wendy Wrench, Karen Bradshaw, Natisha Dukhi
pp. 106–112 · 2013
Objectives To investigate the effects of a service-learning based health promotion elective on knowledge of HIV & AIDS and ways to prevent them. MethodA computer-based quiz, an information poster, an interactive board ga…