Micellar Properties and Antimicrobial Activityof a Mixed Surfactant System Constituted by Sodium Dodecyl Sulfate and Cetylpyridinium Chloride
Deniz Şahin Taş1★, Servet Çete1★ Corresponding author
- 1Faculty of Sciences, Department of Chemistry, Gazi University, Ankara 06500, TURKEY.
CORRESPONDENCE
Deniz Şahin Taş
Faculty of Sciences, Department of Chemistry, Gazi University, Ankara 06500, TURKEY.
Received: 16-09-2016; Revised: 03-01-2017; Accepted: 30-03-2017.
Volume 51, Issue 4 · pp. 580–587 · PUBLISHED 2017 · DOI: 10.5530/ijper.51.4.87
ABSTRACT
Objective: Micellar properties of sodium dodecyl sulfate (NaDS) was examined in the presence of cetylpyridinium chloride (CPC) by means of surface tension, viscosity, dye solubilization, cloud point (CP) measurements.Antimicrobial activities of single and binary systems were also investigated. Results: A decrease in critical micelle concentration (CMC) and increase in solubilizing power for NaDS was observed with increasing CPC concentration. At the highest CPC concentration studied (0.1 M), the surface tension decreased up to 51 mN / m.Also, viscosity results showed growth in NaDS micelles (50 mM) up to the 0.1 M CPC concentration. Antimicrobial activity of NaDS, CPC and NaDS in presence of CPC was investigated against ten different strains of bacteria and ayeast which was not investigated up to now. The susceptibilities of the microorganism were determined by the agar diffusion method. The results showed that NaDS and CPC have a antimicrobial activity but NaDS in presence of CPC has not antimicrobial activity on the bacterial and yeast.
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Taş, D. A., & Çete, S. (2017). Micellar Properties and Antimicrobial Activityof a Mixed Surfactant System Constituted by Sodium Dodecyl Sulfate and Cetylpyridinium Chloride. Indian Journal of Pharmaceutical Education and Research, 51(4), 580–587. https://doi.org/10.5530/ijper.51.4.87