Volume 54, Issue 2S

Liew Kai Bin, Ashok Kumar Janakiraman, Fashli Syafiq Abd Razak, A.B.M. Helal Uddin, Md Zaidul Islam Sarker, Long Chiau Ming, Bey Hing Goh

pp. s1–s11 · DOI: 10.5530/ijper.54.2s.56 · 2020

Over the past two decades, supercritical fluid technology has emerged as one of the most important technologies applied in many fields such as cosmetic, food and pharmaceutical. Supercritical fluid extraction process off…

Aneesh Muvva, Indhu Annie Chacko, Vivek Ghate, Shaila Angela Lewis

pp. s12–s18 · DOI: 10.5530/ijper.54.2s.57 · 2020

Treatment of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome and colonic cancer by targeting drug to the colon is a viable approach. Due to gastric degradation of drugs, proteins and …

Lakshmi Prasanthi Nori, Prasuna Ravi

pp. s19–s31 · DOI: 10.5530/ijper.54.2s.58 · 2020

The regulatory environment for biologics is continuously evolving, because they are ensuring the targeted therapies for many dreadful diseases. But the high cost of biologics has made the European Union to go for the bio…

Vinod Kumar Yadav, Devegowda Vishakante Gowda, Balamuralidhara Veeranna

pp. s32–s42 · DOI: 10.5530/ijper.54.2s.59 · 2020

Background: A suitable drug delivery system has been work on the strategy to enable safe and effective therapeutic efficacy. Drug discovery program, it has huge number of drug molecules are lipophilic as poor aqueous sol…

Asma Saqib, Sharath Pattar, Chandrakant S Karigar, Shailasree Sekhar

pp. s43–s55 · DOI: 10.5530/ijper.54.2s.60 · 2020

Context: Caspases, a family of cysteine-aspartic proteases have a pivotal role in apoptotic pathways. Their down-regulation is reported to induce inappropriate cell survival and enhanced carcinogenic potential. Screening…

Sinjini Mondal, Saurav Moktan

pp. s56–s66 · DOI: 10.5530/ijper.54.2s.61 · 2020

Background: Carapichea ipecacuanha (Brot.) L. Andersson is the botanical source of Ipecac drug and contains major alkaloids emetine, cephaline that are pharmaceutically used against bronchitis associated with cough in ch…

Smriti Tripathi, Papiya Mitra Mazumder

pp. s67–s74 · DOI: 10.5530/ijper.54.2s.62 · 2020

Alzheimer's disease (AD) is a neurological degenerative condition described by a progressive decline in memory and associated with dementia. This disease arises usually after 65 years in individuals. Oxidative stress is …

Bahubali Gundappa Nagavi, M. Chandra Sekar

pp. s75–s78 · DOI: 10.5530/ijper.54.2s.63 · 2020

Aim: To study the impact of Modular Faculty training on the attitude of faculty, motivation towards self–directed learning and team learning. Train the faculty on new teaching and learning tools and assessment. Assess th…

Tamer Mohamed Shehata, Mohammed Abdou Khedr, Maged Elsayed Mohamed

pp. s79–s87 · DOI: 10.5530/ijper.54.2s.64 · 2020

Background: 2,4-Dichlorophenoxy acetic acid (2,4-D) was recently rediscovered as new anti-inflammatory agent through an in silico molecular modeling and in vivo anti-inflammatory inspection. Further computational investi…

Vankayala Devendiran Sundar, Pamu Divya, Magharla Dasaratha Dhanaraju

pp. s88–s97 · DOI: 10.5530/ijper.54.2s.65 · 2020

Introduction: The purpose of the present study was to design develop and characterize the tramadol hydrochloride loaded transethosomal gel formulation for effective pain management. Materials and Methods: The transethoso…

Swapnila Vivek Shinde, Shraddha Phatak, Ganesh Awale, Supriya Nikam

pp. s98–s107 · DOI: 10.5530/ijper.54.2s.66 · 2020

Aim and Objectives: The present study was to formulate and evaluate orodispersible films to overcome drawbacks of conventional dosage forms such as degradation by first-pass hepatic metabolism, decreased bioavailability …

Atul Phatak, Dhanashri Joshi, Mahesh Bhadgale, Pravin Chaudhari

pp. s108–s116 · DOI: 10.5530/ijper.54.2s.67 · 2020

Objectives: The aim of present study was to formulate and optimize Multi-unit Naproxen Sodium controlled release tablet by QbD approach. Controlled release dosage form for naproxen sodium was selected to reduce dosing fr…

Suddala Shirisha, Ankam Saraswathi, Sunit Kumar Sahoo, Yamsani Madhusudan Rao

pp. s117–s127 · DOI: 10.5530/ijper.54.2s.68 · 2020

Background: Nisoldipine is an anti hypertensive drug. Nisoldipine exhibits poor oral bioavailability (5%) because of rapid metabolism in the gut and liver. To overcome hepatic first pass metabolism and to enhance bioavai…

Rudra Pratap Singh, Ramakant M Narke, Pooja V Jadhav

pp. s128–s139 · DOI: 10.5530/ijper.54.2s.69 · 2020

Background: Niosomes are the non-ionic surface-active agent primarily based vesicles. The Key obstacle of Asenapine maleate have oral bioavailability (<2%) and extensive first pass effect. Objectives: The objective key o…

Ullas Prakash D'Souza, Nitish Rao, Ravi Gundadka Shriram, Akhilesh Dubey

pp. s140–s153 · DOI: 10.5530/ijper.54.2s.70 · 2020

Introduction: Super-magnetically modulated nanosphere of carboplatin (CPt) capped with vitamin C and uncapped Nano sphere of CPt were developed and evaluated for their use as a targeted drug delivery system. Objectives: …

Sandeep Divate Sathyanarayana, Narayana Charyulu Rompicherla, Anoop Narayanan Vadakkepushpakath, Prashant Nayak

pp. s154–s162 · DOI: 10.5530/ijper.54.2s.71 · 2020

Background: In recent years, ophthalmic in situ gels have gained wide importance for the sustained delivery of drugs into the eye by overcoming the demerits of conventional eye drops. Objectives: The present investigatio…

Priya Gupta, Rupa Mazumder, Swarupanjali Padhi

pp. s163–s172 · DOI: 10.5530/ijper.54.2s.72 · 2020

Objectives: Glycerosomes represent novel drug delivery systems and are characterised by addition of different amounts of glycerol to liposomal preparations. The present research work aims to formulate eyedrops of natamyc…

Shubhangi Kagade, Jignasa Savjani, Dattatraya Yadav, Prashant Gurav

pp. s173–s181 · DOI: 10.5530/ijper.54.2s.73 · 2020

Aim: The present study was aimed to Design and evaluation of microsponge based drug delivery system of Isoxsuprine Hydrochloride. The microsponge drug delivery system is designed for site specific and controlled release …

Kaustubh Sunil Hiray, Suresh Palamadai Krishnan

pp. s182–s188 · DOI: 10.5530/ijper.54.2s.74 · 2020

Aim: Our study focuses on the liposome-based nanoformulation, which can encapsulate Pterostilbene for its subsequent testing in relevant, model systems for cancer. Background: Pterostilbene, a plant-derived, hydrophobic,…

Sai Surya Nikitha Upadhyayula, Raman Sureshkumar, S K Janani, Chenmala Karthika

pp. s189–s199 · DOI: 10.5530/ijper.54.2s.75 · 2020

Objectives: Development of nano-emulsion based drug delivery as combined drug loaded form for the possible management of meningitis. Intranasal delivery of nano-emulsion to the brain and study the nasal irritancy. Method…