Volume 55, Issue 1

Original Article(continued)

1. Article

   Inhibitory Potential of Dietary Phytocompounds of Nigella sativa against Key Targets of Novel Coronavirus (COVID-19)

   Pratibha Pandey, Fahad Khan, Avijit Mazumder, Ansh Kumar Rana, Yashvi Srivastava

   pp. 190–197 · DOI: 10.5530/ijper.55.1.21 · 2021

   Aim/Background: Dietary factors have shown important role in the rapid management of several human ailments including viral infections. Since ancient times, constituents of Nigella sativa seeds have been utilized as food…

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2. Article

   Safety Evaluation of Syzygium jambolanum on the Development of Zebrafish Embryos

   Mahima Sharma, Suneel Prajapati, Arun Kumar, Ashish Tripathi, GV Narasimha Kumar, Pankaj Gupta

   pp. 198–204 · DOI: 10.5530/ijper.55.1.22 · 2021

   Background: Gestational diabetes mellitus, a hyperglycaemic condition that develops at the time of pregnancy, causes approximately 7% of complications during pregnancies world wide. Syzygium jambolanum has been proved cl…

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3. Article

   Antiproliferative Potential of Ethyl acetate Extract of Clerodendrum thomsoniae Balf.f. on DMBA-induced Breast Cancer in Female Sprague-dawley Rats

   VK Muhammed Ashraf, VK Kalaichelvan, R Ragunathan, VV Venkatachalam

   pp. 205–214 · DOI: 10.5530/ijper.55.1.23 · 2021

   Background: Clerodendrum is a genus of around 500 species that has a place with the family Lamiaceae. Numerous types of this class have been demonstrated for the treatment of different maladies including cancer. This stu…

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4. Article

   Ameliorative Effect of Multi Herbal Formulation on Lipid Peroxidation and Redox Dysfunction in Ethanol Induced Hepatic Imbalance

   Soumendra Darbar, Srimoyee Saha, Kaushikisankar Pramanik, Atiskumar Chattopadhyay

   pp. 215–223 · DOI: 10.5530/ijper.55.1.24 · 2021

   Objectives: Traditional medicine is a potent antioxidant. In the present study, we developed a multi herbal formulation and examined its anti-oxidative activities and possible protective effect of it on serum and liver l…

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5. Article

   Bioactivity of Dodecanoic Acid Extracted from Geitlerinema sp. TRV57

   Renugadevi K, Valli Nachiyar C, Moin Zaveri

   pp. 224–231 · DOI: 10.5530/ijper.55.1.25 · 2021

   Aim/Background: Imbalance in oxidant and antioxidant leads to oxidant stress. Increased consumption of exogenous antioxidants helps in neutralizing the oxidant stress and thus protects the cells from oxidant stress. The …

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6. Article

   Evaluation of Anti-urolithiatic Potential of Leaves of Alstonia scholaris and its Isolated Pentacyclic Triterpenoids in Ethylene Glycol-induced Renal Calculi Rat Model

   Zehra S, Sanaye MM

   pp. 232–239 · DOI: 10.5530/ijper.55.1.26 · 2021

   Introduction: Urolithiasis has afflicted human race since the days of yore. Conventional treatment acts only on associated ailments whereas pharmacologically active phytoconstituents derived from plants are reported to p…

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7. Article

   Tribulus terrestris Saponins Improve Ovarian Ischemia-reperfusion Injury in Female Rats: Modulation of Vascular Endothelial Growth Factor-A and Hemeoxygenase-1

   Asmaa Mohamed Abdel-Aziz, Hanaa Hassanein Mohammed, Osama Abdelazem, Rasha Fouad Ahmed, Yasmine F. Ibrahim

   pp. 240–248 · DOI: 10.5530/ijper.55.1.27 · 2021

   Aim/Background: Ovarian I/R is a popular gynecological emergency, complicating ovarian torsion. TTS, reported to have many therapeutic effects along with being an antioxidant, anti- inflammatory and anti-apoptotic agent.…

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8. Article

   Appliance of the ICH Guidelines: Forced Degradation Studies on Abafungin and Development of Validated Stability Indicating Method by 1st Order Derivative Spectroscopy

   Swati Pandey, Ravindra Pandey, Shiv Shankar Shukla

   pp. 249–255 · DOI: 10.5530/ijper.55.1.28 · 2021

   Background: The presented study is a stability indicating simple, precise and accurate 1st order UV derivative spectroscopic method that is being studied under the different stated International Council for Harmonization…

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9. Article

   Docking Studies, Synthesis and Evaluation of Anticancer Activity of 4H-Chromene Derivatives

   Piyush Kumar, Pinki Rawat

   pp. 256–265 · DOI: 10.5530/ijper.55.1.29 · 2021

   Aim: The present study involves to design, synthesis and evaluate the anticancer activity of 4H-chromene derivatives (PKB 1-10) on human breast cancer MCF-7 cell line. Materials and Methods: 4H-chromene derivatives (PKB …

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10. Article

    Design, Synthesis, Hypoglycemic Activity and Molecular Docking Studies of 3-substituted-5- [(furan-2-yl)-methylene]-thiazolidine-2,4-dione Derivatives

    Karumanchi Srikanth Kumar, Atmakuri Lakshmana Rao, Dachuru Rama Sekhara Reddy

    pp. 266–275 · DOI: 10.5530/ijper.55.1.30 · 2021

    Background: From the wide range of previous literature studies indicated that thiazolidinedione’s reacts with substituted benzaldehydes undergoes knoevenagel condensation gives respective arylidene derivatives. In our at…

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11. Article

    Research on the Attitudes of the Elderly towards Interprofessional Cooperation and Collaborative Pharmacy Practices: Cross-sectional Study in Serbia

    Velibor O Ilić, Ljiljana Tasić, Valentina Marinković

    pp. 276–287 · DOI: 10.5530/ijper.55.1.31 · 2021

    Background: Population aging is taking place at the highest historical rates, while growing needs for healthcare by the elderly put added and immense pressure predominantly on the primary care. Higher level of interprofe…

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12. Article

    Re-Appraisal of the Effectiveness and Adverse Reaction between Cefazolin and Anti-Staphylococcal Penicillins for Treating Patients with Methicillin- Sensitive Staphylococcus aureus Bacteremia: Comprehensive Meta-analysis and Trial Sequential Analysis

    Chang-Hua Chen, Yu-Min Chen, Hsien-Meng Chen, Yu-Jun Chang, Li-Jhen Lin, Hua-Cheng Yen

    pp. 288–303 · DOI: 10.5530/ijper.55.1.32 · 2021

    Objectives: Patients with methicillin susceptible Staphylococcus aureus bacteremia (MsSaB) are treated by cefazolin (Cfz) or anti-staphylococcal penicillin’s (ASPs) as the preference drug, although they may be not equall…

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