Volume 55, Issue 2

Sudipta Das, Rimi Dey, Amit Kumar Nayak

pp. 304–318 · DOI: 10.5530/ijper.55.2.68 · 2021

Artificial Intelligence (AI) focuses in producing intelligent modelling, which helps in imagining knowledge, cracking problems and decision making. Recently, AI plays an important role in various fields of pharmacy like …

Abhinav Raj Ghosh, Bhooshitha AN, Chandan HM, KL Krishna

pp. 319–329 · DOI: 10.5530/ijper.55.2.69 · 2021

Aim: The aims of this review are to assess the anti-viral and targeting strategies using nano materials and the possibility of using Silver nanoparticles for combating the SARS-CoV-2. Background: The novel Coronavirus (S…

Praharsh Kumar Mandadhi Rajendra, Natarajan Jawahar, Rajeshkumar Raman, Hagalavadi Nanjappa Shivakumar, Anjali Puthusserikkunnu Balan

pp. 330–335 · DOI: 10.5530/ijper.55.2.70 · 2021

Purpose: To summarize main findings from research on oral delivery of Nanostructured lipid carriers targeting ovarian cancer. Methods: A narrative review of all the relevant papers known to author was conducted. Results:…

Nandhini B, MP Venkatesh, TM Pramod Kumar

pp. 336–345 · DOI: 10.5530/ijper.55.2.71 · 2021

The nutraceuticals in India are termed as "Foods for Special Dietary Uses" Food Safety and Standards Authority describes "Nutraceuticals provide a physiological benefit and help to maintain good health." FSSAI was recogn…

Kousalya Prabahar, Zahraa Alanazi, Mona Qushawy

pp. 346–353 · DOI: 10.5530/ijper.55.2.72 · 2021

Drug targeting is a new drug delivery system that aims to deliver the drug to the target site of action or site of absorption without releasing the drug at any other non-target site. The delivery system is designed to re…

Sunil Kumar, Naveen Goyal

pp. 354–362 · DOI: 10.5530/ijper.55.2.73 · 2021

Aim: To formulate a Micro particulate system using central composite design to remain in the stomach for prolonged time and used for Gastroretentive drug delivery. Materials and Methods: Gastroretentive Microspheres were…

Monika Shirke, Monali Gangthade, Pratip Chaskar, Rakesh Somani

pp. 363–373 · DOI: 10.5530/ijper.55.2.74 · 2021

Background: Biphenyl based 4-thiazolidinones are found to possess a wide range of activities resulting in their synthesis. Methods: Eight molecules (VIIa-VIIh) were profoundly synthesized using four step procedures. Thes…

Ananya Basu, Rajashree Shashidhar Masareddy, Archana Patil, Uday Bolmal

pp. 374–382 · DOI: 10.5530/ijper.55.2.75 · 2021

Background: This in situ solution which on gelation floats in the gastric region is suitable for sustaining the release of the drug. In the present research work, Ropinirole Hydrochloride which is an Anti-parkinson agent…

Marina Koland, Rakshitha Bhaskar Anchan, Sawan Ghetia Mukund, Sindhoor Shridharan Mulleria

pp. 383–394 · DOI: 10.5530/ijper.55.2.76 · 2021

Introduction: The conventional subcutaneous administration of insulin has been associated with several limitations leading to poor patient compliance. The poor oral bioavailability of insulin due to degradation by gastro…

Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education, Research (RIPER)-Autonomous, KR Palli Cross, Chiyyedu Chiyyedu, Anantapur Anantapur, Andhra Pradesh, INDIA. Department of Pharmacology, INDIA. INDIA.

pp. 395–406 · DOI: 10.5530/ijper.55.2.77 · 2021

Objectives: The present work was designed to formulate extended-release tablets of clarithromycin by means of central composite design. To assess the systematic considerate of input and output variables and to construct …

Seema Mahor, Phool Chandra, Neelkant Prasad

pp. 407–417 · DOI: 10.5530/ijper.55.2.78 · 2021

Objectives: In the present investigation a novel oral drug delivery system was developed by combining two different techniques floating and mucoadhesive system so called floatadhesive, in order to obtain a controlled sys…

Harshitha Chandrashekar, Sayani Bhattacharyya

pp. 418–427 · DOI: 10.5530/ijper.55.2.79 · 2021

Introduction: Formulation of a nano lipid carrier loaded hydrophilic gel of a corticosteroid, fluticasone propionate (FP) was investigated systemically with response surface model (RSM) for promising dermal delivery of t…

Wan Nurul Huda Wan Zainal, Enidran Loganathan, Thavakumara Ganesan

pp. 428–435 · DOI: 10.5530/ijper.55.2.80 · 2021

Propolis is a resinous material collected by bees from various plant sources. Propolis has been used since ancient times for medicinal purposes. In this study, the propolis extracts were dried using a freeze-drying techn…

Mansour Abdulnabi Hadi Mehdi, Vidya Pradhan, Mazahar Farooqui, Fadel Yousif Salah Alarabi, Gozif Mohammed Nasr Omar

pp. 436–444 · DOI: 10.5530/ijper.55.2.81 · 2021

Objectives: This research was designed to examine improvements in some heamatological parameters of Entamoeba histolytica-infected rats treated with extracts of Reseda sphenocleoides leaves. Methods: Twenty rats weighing…

Alfredo Madariaga-Navarrete, Eliazar Aquino-Torres, Raquel Cariño-Cortés, Roberto Villagómez-Ibarra, Juan Ocampo-López, Ashutosh Sharma, Alma Delia Hernández-Fuentes

pp. 445–454 · DOI: 10.5530/ijper.55.2.82 · 2021

Introduction: Diabetes is a worldwide pandemic disease with an expensive way of control. Locals around the world have been used botanical extracts to reduce the effects of this deadly disease to improve the quality of li…

Choudhury Priyabati, Adhikari Lopamudra, Pattanaik Sovan

pp. 455–462 · DOI: 10.5530/ijper.55.2.83 · 2021

Background: Olax psittacorum, a flowering plant grown in open forests, is consumed by the locals as dietary sources. Aim: This study was designed to check the phytochemical screening, antioxidant activity, antimicrobial …

Punabaka Jyothi, Kuna Yellamma

pp. 463–473 · DOI: 10.5530/ijper.55.2.84 · 2021

Background: Alzheimer's disease (AD) hallmark feature is neurodegeneration due to the accumulation of β-amyloid plaques and the formation of neurofibrillary tangles in the aged brain. The prevalence of AD in humans is do…

Aishwarya Laxman Thakur, Kalpana Sabanna Patil

pp. 474–482 · DOI: 10.5530/ijper.55.2.85 · 2021

Background: Phytosomes are newly introduced novel dosage form for improving the bioavailability and therapeutic effect of the herbal drug. The present study aimed to prepare and evaluate the alkaloid loaded phytosome fro…

Arafa Musa, Mohammad Mahmoud Al-Sanea, Nasser Hadal Alotaibi, Taghreed Stum Alnusaire, Shaimaa Rashad Ahmed, Ehab Mohamed Mostafa

pp. 483–490 · DOI: 10.5530/ijper.55.2.86 · 2021

Introduction: Kinase enzymes play an important role in cellular proliferation, the main target in cancer treatment is to inhibit their functions. Protein kinase inhibitors as flavonoids can be applied for prevention or t…

Okan Arihan, Omer Akgul, Gokhan Oto, Serkan Yildirim, Huseyin Eroglu, Gulhan Bora

pp. 491–497 · DOI: 10.5530/ijper.55.2.87 · 2021

Background: Burn wound is an important health problem worldwide. Serious outcomes related with burn occur and treatments focus on healing of the wounded area with dermal preparations containing chemicals avoiding growth …