Review

Drug Repurposing: A Potentially Emerging Discipline

Praveen Kumar1★, Mariam Mammen1, Aswathy Madhusoodhanan1, Archana Geetha Mohanan1, Pradeep Kumar Ravindrannair1,2, Anilkumar Appu Kuttan3, Sheeba Madhavan Sathi3, Mathew Steephan3★ Corresponding author

  1. 1Department of Zoology, Government College for Women, Thiruvananthapuram, Kerala, INDIA.
  2. 2Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, INDIA.
  3. 3Department of Botany, Government College for Women, Thiruvananthapuram, Kerala, INDIA.

CORRESPONDENCE

Praveen Kumar

Department of Zoology, Government College for Women, Thiruvananthapuram, Kerala, INDIA.

praveen@gcwtvm.ac.in

Received: 13-06-2021; Revised: 02-12-2021; Accepted: 02-04-2022.

Volume 56, Issue 2S · pp. S121–S136 · PUBLISHED 2022 · DOI: 10.5530/ijper.56.2s.83

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ABSTRACT

Drug repurposing is the remodeling of already existing drugs to reduce the time frame, costs, and efforts in developing a new novel drug. This strategy has secured significant momentum in the previous decade. It overcomes the snags and pitfalls in the traditional means of drug discovery. This core research strategy has now become the sole approach to containing many deadly diseases that have no cure in the present. In astound, for pandemics like COVID-19 that is spreading like a wildfire worldwide, large-scale research programs and trials have been carried out to identify and modify existing drugs to counter the novel virus. Thus, this technology of drug repurposing offers a new lease of life, and greatly promotes the progress of the medicine, health, and pharma sectors. The purpose of this study is to understand the current status of drug repurposing in the field of virology, bacteriology, mycology, and oncology for clinical translatability.

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    Kumar, P., Mammen, M., Madhusoodhanan, A., Mohanan, A. G., Ravindrannair, P. K., Kuttan, A. A., Sathi, S. M., & Steephan, M. (2022). Drug Repurposing: A Potentially Emerging Discipline. Indian Journal of Pharmaceutical Education and Research, 56(2S), S121–S136. https://doi.org/10.5530/ijper.56.2s.83