jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Indian Journal of Pharmaceutical Education and ResearchNOW IN
Review

Recent Advances and Appropriate Use of Niosomes for the Treatment of Skin Cancer

Pottathil Shinu1★, Anroop B Nair2, Beena Kumari3, Shery Jacob4, Manish Kumar5, Abhishek Tiwari6, Varsha Tiwari6, Katharigatta N Venugopala2,7, Mahesh Attimarad2, Sreeharsha Nagaraja2,8★ Corresponding author

  1. 1Department of Biomedical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, SAUDI ARABIA.
  2. 2Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, SAUDI ARABIA.
  3. 3Department of Pharmaceutics, Indira Gandhi University, Meerpur, Rewari, Haryana, INDIA.
  4. 4Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, Ajman, UAE.
  5. 5Department of Pharmaceutics, M.M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University) Ambala, Haryana, INDIA.
  6. 6Department of Pharmaceutical Sciences, Pharmacy Academy, IFTM University, Moradabad, Uttar Pradesh, INDIA.
  7. 7Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban, SOUTH AFRICA.
  8. 8Department of Pharmaceutics, Vidya Siri College of Pharmacy, Off Sarjapura Road, Bangalore, Karnataka, INDIA.

CORRESPONDENCE

Pottathil Shinu

Department of Biomedical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, SAUDI ARABIA.

spottathail@kfu.edu.sa

Received: 07-06-2022; Revised: 18-07-2022; Accepted: 26-08-2022.

Volume 56, Issue 4 · pp. 924–937 · PUBLISHED 2022 · DOI: 10.5530/ijper.56.4.170

View on IJPER original site ↗

ABSTRACT

Both melanoma and non-melanoma are the most common types of skin cancers affecting various populations across the globe. Skin malignancy is more prevalent among Caucasian populations. Non-melanoma types of skin cancers are further classified as basal cell and squamous cell carcinomas, respectively. The incidence of non-melanoma type of cancers is relatively higher than melanoma type of skin cancers. Recently published data shows that melanoma of the skin stands as the seventeenth most common type of cancer across the world. Niosome is a drug carrier in a novel drug delivery system wherein the drug is enclosed within the vesicle, which is made up of non-ionic surfactants that are stabilized by the addition of cholesterol. Niosomes help to overcome certain difficulties of skin drug deliveries such as insolubility, instability, low bioavailability, and fast debasement of medications. This review article mainly focuses on the use of niosomes in dermatology particularly aiming at the delivery of drugs via skin. In addition, this review discusses the specific use of niosomal drug delivery systems that may be useful in clinics. The niosomes are gaining popularity in the field of topical drug delivery due to their excellent characteristics like proficiency to carry both hydrophilic and lipophilic drugs, increasing the penetration of drugs, and enhancing drug stability and drug release at sustained levels.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Shinu, P., Nair, A. B., Kumari, B., Jacob, S., Kumar, M., Tiwari, A., Tiwari, V., Venugopala, K. N., Attimarad, M., & Nagaraja, S. (2022). Recent Advances and Appropriate Use of Niosomes for the Treatment of Skin Cancer. Indian Journal of Pharmaceutical Education and Research, 56(4), 924–937. https://doi.org/10.5530/ijper.56.4.170