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Indian Journal of Pharmaceutical Education and ResearchNOW IN
Article

Comparison between Olive Oil and Nano-Bio Fusion Gel and their Role in the Treatment of Alveolar Osteitis: A Double-Blind Randomized Trial

Zafar Ali Khan1, Namdeo Prabhu1, Naseer Ahmed2, Rakhi Issrani3★★ Corresponding author

  1. 1Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka, SAUDI ARABIA.
  2. 2Department of Prosthodontics, Altamash Institute of Dental Medicine, Karachi, PAKISTAN.
  3. 3Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, SAUDI ARABIA.

CORRESPONDENCE

Rakhi Issrani

Lecturer, Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, SAUDI ARABIA.

dr.rakhi.issrani@jodent.org

Received: 07-09-2022; Revised: 20-12-2022; Accepted: 22-02-2023.

Volume 57, Issue 2S · pp. s315–s320 · PUBLISHED 2023 · DOI: 10.5530/ijper.57.2s.36

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ABSTRACT

Background: Alveolar osteitis is a painful condition that occurs after tooth extraction. This condition has been treated with various chemical and herbal formulations that are found to be efficacious with different success rates. Objectives: The present study is aimed to evaluate and compare the efficacy of organic olive oil and Nano-Bio Fusion (NBF) gel in the management of alveolar osteitis. Materials and Methods: 90 patients who were diagnosed with alveolar osteitis following non-surgical dental extractions were selected and randomly divided into two groups. The extraction socket was irrigated with warm normal saline followed by insertion of sterile gauze soaked in organic olive oil in Group I patients (n=45) and with NBF gel in Group II patients (n=45). The patients were recalled for the change in dressings on day 3, day 5 and day 7. The subjects were evaluated for the following parameters on 7th day; pain, gingival erythema, granulation tissue and the extraction socket margin. Data were analyzed using Friedman test and Mann-Whitney U test. P≤0.05 was considered statistically significant. Results: The mean VAS score on day 1 for group I was 8.9 and group II was 8.6. The mean VAS score for both the groups was zero on day 7 though the participants of group II reported better pain relief from day 3 to day 7 when compared with group I patients. Subjects treated with olive oil showed a mildly inflamed gingival to a normal pink variant on day 7. However, all the subjects treated with NBF gel presented with healthy pink gingival on day 7. There was significant improvement in the healing of the margin in both cases. Conclusion: Compared to the olive oil, NBF gel helps in enhanced healing in cases of alveolar osteitis.

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    Khan, Z. A., Prabhu, N., Ahmed, N., & Issrani, R. (2023). Comparison between Olive Oil and Nano-Bio Fusion Gel and their Role in the Treatment of Alveolar Osteitis: A Double-Blind Randomized Trial. Indian Journal of Pharmaceutical Education and Research, 57(2S), s315–s320. https://doi.org/10.5530/ijper.57.2s.36