Volume 59, Issue 2

Lihui Wang, Wei Fei, Chongjuan Qin, Jing Zhang

pp. 647–654 · DOI: 10.5530/ijper.20250344 · 2025

Background Globally, Diabetic Retinopathy (DR) is a leading cause of vision loss. This disease, which impacts the microvasculature of the retina, is brought on by the oxidative stress linked to diabetes. Several studies …

Guang Yang, Rui Cai

pp. 673–681 · DOI: 10.5530/ijper.20250368 · 2025

Aim To study the Kaempferol (Kaem) on Pentetrazol (PTZ)-induced chronic epileptic rats, and to explore its effect on nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)/ caspase-1/gasdermin D (GSDMD…

Krishna Kant Gupta, Yatindrapravanan Narasimhan, Shashank Ravichandran, Brindha Pemaiah, Davidraj Chellappan, Ragothaman Madhava Rao Yennamalli, Sriram Sridharan

pp. 682–694 · DOI: 10.5530/ijper.20256024 · 2025

Background Kabasurak kudineer (Kk), a traditional Siddha formulation containing 15 plant-based ingredients has been prescribed in Siddha medicine for the management and treatment of flu-like symptoms. Currently, the Mini…

Shaeena MH, Bharathi D.R

pp. 704–711 · DOI: 10.5530/ijper.20250571 · 2025

Background Plectranthus amboinicus(Lour.) Spreng, a member of the Lamiaceae family, is commonly utilized in both traditional medicine and culinary applications. This research focuses on optimizing the pharmacodynamic and…

Shuhong Xu, Boyang Yu

pp. 712–718 · DOI: 10.5530/ijper.20252630 · 2025

Background Traditional Chinese Medicine (TCM) has shown unique advantages in the prevention and treatment of chronic complex diseases, emergency treatment and major infectious diseases, especially COVID-19 epidemic. Refo…

Mohammed Albratty, Hafiz A Makeen

pp. 719–726 · DOI: 10.5530/ijper.20257442 · 2025

Background Curcumin-SnO2 Nanoparticles (NPs) are advanced materials that combine organic molecules and inorganic substances in a single nanoscale platform to create hybrids with unique and enhanced properties. The synerg…

Xinglei Xiao, Shanglun Liu, Guoqing Chen, Chen Cao

pp. 727–737 · DOI: 10.5530/ijper.20257346 · 2025

Background Oxidative stress and inflammation are suggested to be the major etiological factors for the autoimmune disease rheumatoid arthritis. Rheumatoid arthritis affects millions of individuals all over the world even…

Amal Alghamdi, Kholoud Hesham, Shahad Alghamdi, Aya Kadi, Aeshah Aljohani, Amal Shori

pp. 738–746 · DOI: 10.5530/ijper.20250239 · 2025

Background Lactic Acid Bacteria (LAB) produce bacteriocins, which have recently attracted considerable interest as alternatives to antibiotics. Cheese, a fermented food rich in LAB, is highly perishable and susceptible t…

Li Wu, Feizhang Qin, Chengcheng Zhao, Ping Hou

pp. 747–756 · DOI: 10.5530/ijper.20257348 · 2025

Background Myocardial Infarction (MI) is a prevalent condition of heart disease. Despite remarkable growth in the treatment of heart diseases, MI remains the foremost cause of mortality worldwide and a significant pathol…

Shakila Baby, Nouf M. Alyami, Hossam M. Aljawdah, Sulaiman Ali Alharbi, Palanisamy Arulselvan, Saravana Kumar Jaganathan, Samer Hasan Hussein-Al-Ali, Bharathi Muruganantham

pp. 757–766 · DOI: 10.5530/ijper.20257391 · 2025

Background Nanotechnology has emerged as a novel research area to address the several problems associated with existing cancer treatments. Objectives The present work was focused on synthesizing and characterizing the ti…

Jinhui Liu, Sheng Liu, Chunming Li

pp. 767–776 · DOI: 10.5530/ijper.20251689 · 2025

Aim/Background Bone Marrow (BM) Mesenchymal Stem Cells (MSCs) possess significant clinical potential, yet their limited expansion ability in the laboratory restricts their broad application. While cytokines and pharmaceu…

pp. 777–782 · DOI: 10.5530/ijper.20250945 · 2025

Background Pranic Healing is a complementary therapy that uses specific colours to enhance the healing of wounds. Objectives Our research sought to investigate the impacts of integrating various Pranic Healing (PH) colou…

Lili Gao, Jie Qi

pp. 783–789 · DOI: 10.5530/ijper.20250460 · 2025

Background Novel pharmaceuticals have been largely derived from natural substances. Through this experimental study, we sought to assess the impacts of Isoliensinine (ILS) on Acute Lung Injury (ALI) and sepsis caused by …

Hima Saila Mukkudiahgari, Ramesh Reddy Kudamala, Santhrani Thakur

pp. 790–799 · DOI: 10.5530/ijper.20257027 · 2025

Background Thymol, a monoterpene phenolic compound and an essential oil extracted from Tachyspermum ammi (ajwain) has been shown to possess multiple therapeutic potentials as anti-inflammatory, antioxidant, antihyperlipi…

Guangtao Zheng, Dan Gao, Lei Wang, Ke Zhou

pp. 800–809 · DOI: 10.5530/ijper.20250474 · 2025

Background Colon cancer is the third major type of cancer globally and the second most reason for cancer-associated mortality. Natural products (phytochemicals) are considered safer alternatives to treat colon cancer. Ob…

Rabia Mrehil Elsalami, Kamal Rullah, Yaman Walid Kassab, Mohammad Javed Qureshi, Waqas Ahmad, Mahani Mahadi, Masriana Hassan, Noraziah Mohamad Zin, Anwar Salm Kalifa Kafo, Chin Chai Yee, Najwa Mohamad

pp. 810–825 · DOI: 10.5530/ijper.20255518 · 2025

Aim/Background Aurone is a well-known, naturally occurring, minor flavonoid with significant biological properties. However, their low abundance in nature limits their application in the medical field. In this study, we …

Ling Zhu, Zhiyao Li, Jing Dong

pp. 826–840 · DOI: 10.5530/ijper.20250379 · 2025

Background Oral Squamous Cell Carcinoma (OSCC) is a prevalent and aggressive form of cancer with limited effective therapeutic options. This study explores the potential anticancer effects of ursolic acid and its mechani…

Swati Devendra Raysing, Ashish Prakash Gorle

pp. 841–848 · DOI: 10.5530/ijper.20254922 · 2025

Background The purpose of the recent research was to establish a simple, efficient, sensitive and accurate High-Performance Liquid Chromatography (HPLC) method for estimating Resveratrol (RVT) in bulk and pharmaceutical …

Yuan Fang, Li Meng, Ruifen Zhang

pp. 695–703 · DOI: 10.5530/ijper.20250444 · 2025

Background Glaucoma, a progressive optic neuropathy characterized by optic nerve injury, is a pivotal cause of vision loss globally. Objective: The current work focuses on assessing the therapeutic role of cardamonin aga…

Narendra Kumar Jain

pp. 849–853 · DOI: 10.5530/ijper.20250981 · 2025

Quality healthcare has been universally recognized as a fundamental human right, but sadly, this right is not sufficiently fulfilled globally. The goal of healthcare 4.0 is to completely revolutionize the healthcare deli…