Volume 59, Issue 2S

Prathap Madeswara Guptha, Vijayaraj Surendran, Raghavendra Kumar Gunda

pp. s399–s409 · DOI: 10.5530/ijper.20256017 · 2025

Design of Experiments (DOE) is a powerful and systematic approach used in various fields to efficiently plan, execute and analyze experiments. This review provides a comprehensive overview of the application of DOE in th…

Saranraj Loganathan, Rajkumaran Soundarraj, Vishwalingam Murugan Sujetha

pp. s410–s413 · DOI: 10.5530/ijper.20250352 · 2025

Background: The Lecture Capturing System method was implemented in Pharmacy education for a better understanding of the specific content and provides flexibility to review. This study observed pharmacy learners’ perspect…

Madhuri Desai, Shalaka Dhanna, Sujata Jadhav, Akshada Koparde, Akansha Dashwanat, Rutuja Gharal

pp. s414–s425 · DOI: 10.5530/ijper.20250097 · 2025

Introduction: Simvastatin, a BCS II drug, has poor water solubility and low bioavailability. Nanostructured Lipid Carriers (NLCs) can enhance its bioavailability. This study investigates the potential of NLCs to improve …

Sundaramoorthi Revathi, Pavadai Anitha, Sathappan Jenifer, Sivakumar Senthil Rajan

pp. s426–s435 · DOI: 10.5530/ijper.20250227 · 2025

Background: Vildagliptin is a dipeptidyl peptidase-4 inhibitor employed for the intervention of non-insulin-dependent diabetes mellitus which has a short half-life. The intention of this work is to devise and qualify vil…

Kiruthika Santhinathan, Susmitha Durai, Rijivana Sirajudeen, Gopinath Govindhraji, Saravanan Gopal, Gayathri Kumararaja

pp. s436–s442 · DOI: 10.5530/ijper.20250292 · 2025

Background: Cardiovascular Diseases (CVDs) are the main causes of death in both industrialized and developing nations, which are mostly brought on by poor lifestyles and insufficient physical activity. Recent years many …

Charan Sailaja, Pradeep Kumar Bhupalam

pp. s443–s453 · DOI: 10.5530/ijper.20250564 · 2025

Objectives: To improve and optimize loratadine-loaded niosomal transdermal patches with a Box-Behnken Design to enhance drug delivery and evaluate their potential as an effective alternative to oral administration for al…

Purushottam Gangane, Pallavi Ingle, Vijaya Rabade, Harigopal Sawarkar

pp. s454–s463 · DOI: 10.5530/ijper.20253872 · 2025

Aim: The purpose of research was to refine the solubility and dissolution assessment of lurasidone hydrochloride, a poorly water-soluble drug with a pH dependent solubility, by preparing chitosan-based nanoparticles usin…

Ashish Sriram Mishra, Gouranga Dutta, Abimanyu Sugumaran

pp. s464–s472 · DOI: 10.5530/ijper.20254097 · 2025

Introduction: Telmisartan (TLM) is a common angiotensin II receptor antagonist used to treat hypertension. However, the drug's limited bioavailability and delayed onset duration diminish its efficacy. To address these co…

Rajeswari Aleti, Monika Nijhawan, Gunnam Sailaja

pp. s473–s481 · DOI: 10.5530/ijper.20254583 · 2025

Introduction: Early morning surge in blood pressure is a major cause of sudden cardiac arrest. Objectives: Development and evaluation of chronomodulated Compression Coated Tablets (CCT) for bedtime dosing of sacubitril-v…

Prathap Madeswara Guptha, Raghavendra Kumar Gunda, Murugesan Vanangamudi, Elphine Prabahar A

pp. s482–s493 · DOI: 10.5530/ijper.20255422 · 2025

Background: The primary goal of this study is to increase the effective surface area of Almotriptan and improve disintegration time and diffusion time of the tablet by using a direct compression technique for producing F…

Akanksha Dwivedi, Rajesh Sharma

pp. s494–s507 · DOI: 10.5530/ijper.20255506 · 2025

Aim: The present study is focused to develop and optimize nanoparticulate delivery system for two antidiabetic drugs; Sitagliptin Phosphate (SP) and Empagliflozin (EMP) of BCS class III drugs as a single dosage form usin…

Malti Arya, Amit Porwal, Koshy Mamman Kymonil

pp. s508–s522 · DOI: 10.5530/ijper.20255540 · 2025

Background: The goal of this work was to develop, optimise and characterise nanostructured lipid carriers containing methotrexate for the treatment of Rheumatoid Arthritis (RA). As materials and process parameters, solid…

Kumararaja Gayathri, Praveena Gandhi, S. Kiruthika

pp. s523–s530 · DOI: 10.5530/ijper.20255974 · 2025

Background: In comparison to conventional vesicular drug delivery techniques, Pharmacosomes are a potential method for vesicular drug delivery that offers a number of advantages. Pharmacosomes are phosphilipid complexes …

Pranita Sunil Kanojiya, Rita Naresh Wadetwar, Amita Prasanna Godbole

pp. s531–s551 · DOI: 10.5530/ijper.20256191 · 2025

Aim: The present work was carried out to improve the aqueous solubility of Fluconazole by formulation of inclusion complex using β-cyclodextrin and then loaded into the suppository for the treatment of vaginal candidiasi…

Hema Kumar A V, Chamakuri Kantlam

pp. s560–s571 · DOI: 10.5530/ijper.20257237 · 2025

Background: Capsaicin (CAP), a naturally occurring alkaloid, shows many promising benefits but is unexplored due to its hydrophobic nature and limited bioavailability. Objectives: To address these limitations, the presen…

Anita Raj Panigrahi, Shib Swaroop Samal, Srinivas Lankalapalli

pp. s572–s584 · DOI: 10.5530/ijper.20250014 · 2025

Background: Nanoscale delivery systems such as milk exosomes, promising carriers for drug delivery, are used to deliver therapeutic drug molecules to the targeted organs. They possess characteristics that include low imm…

Manish Kushwah, Avijit Mazumder, Richa Shakya, Pankaj Tyagi, Motamarri Venkata Naga Lalitha Chaitanya

pp. s585–s593 · DOI: 10.5530/ijper.20254714 · 2025

Background: Considering the growing preference for herbal medications over their synthetic counterparts it is the need to combat the global end stage renal disease in Diabetic Nephropathy problem. In AYUSH medicine, the …

Om Prakash Dhangar, Talever Singh, Himansu Chopra, Ram Babu Tripathi, Shivendra Kumar, Akash Garg, Kuldeep Singh, Devender Pathak

pp. s594–s601 · DOI: 10.5530/ijper.20255377 · 2025

Background: Anthocephalus cadamba owe their family name to ‘runiaceae’. The plant's primary constituents include triterpenes, glycosides, saponins, flavonoids and indole alkaloids, including isocadambine, cadambine and i…

Bhimana Sasidhar, Ravindran Saravanan

pp. s602–s625 · DOI: 10.5530/ijper.20254639 · 2025

Background: This study aims to optimize the production of α-amylase from Bacillus velezensis sp. through a comparative analysis of advanced experimental methodologies, specifically Definitive Screening Design-Response Su…

Anchit Dogra, Avijit Mazumder, Saumya Das, Pratibha Pandey, Motamarri Venkata Naga Lalitha Chaitanya

pp. s626–s632 · DOI: 10.5530/ijper.20254695 · 2025

Background: Arthritis is a prevalent chronic inflammatory condition that significantly impacts individual’s quality of life. Lactoferrin (Lf), a multifunctional glycoprotein found in CM, has shown promising anti-inflamma…