Article

Review on Exploring the Combination Effect of Aldosterone along with Plasma Renin with Melatonin and Hydro-Cortisol in Diurnal Rhythm

Mainak Pal1, Masud Sk1, Saheli Mandal1, Dipanjan Mandal1★★ Corresponding author

  1. 1Department of Pharmacy, Division of Pharmacology, Guru Nanak Institute of Pharmaceutical Science and Technology, Sodepur, Kolkata, West Bengal, INDIA.

CORRESPONDENCE

Dipanjan Mandal

Department of Pharmacy, Division of Pharmacology, Guru Nanak Institute of Pharmaceutical Science and Technology, Sodepur, Kolkata, West Bengal, INDIA.

dipanjan.mondal@gnipst.ac.in

Received: 19-03-2025; Revised: 07-05-2025; Accepted: 29-07-2025.

Volume 60, Issue 1S · pp. s33–s41 · PUBLISHED · DOI: 10.5530/ijper.20260468

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ABSTRACT

Aldosterone and plasma renin activity play a role in regulating our blood stress and fluid level while melatonin and cortisol help manage our sleep wake cycles as well as our reaction to stress. These hormones go through fluctuations over the day prompted through elements along with posture, salt intake, pressure levels and sleep patterns. The tricky interplay among the structures governing blood stress, fluid balance, circadian rhythm and pressure response is evident from the interconnectedness of these hormones. This evaluates goals to discover the connections between aldosterone, plasma renin activity, melatonin, and cortisol, in rhythms. Additionally, it will investigate how these connections impact conditions and ailments. The reason for this overview is to investigate how aldosterone, PRA, melatonin, and cortisol relate to diurnal rhythms. It examines how these connections may additionally influence some of medical problems, including number one or secondary aldosteronism, high blood pressure, coronary heart failure, renal infection, sleep disturbances, and metabolic syndrome. It additionally emphasizes essential studies supporting the interplay among these hormonal systems. The evaluation analyzes the advantages and disadvantages of the currently available research and makes suggestions for further studies or methods to fill in any gaps or overcome any difficulties in the subject.

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    Pal, M., Sk, M., Mandal, S., & Mandal, D. (). Review on Exploring the Combination Effect of Aldosterone along with Plasma Renin with Melatonin and Hydro-Cortisol in Diurnal Rhythm. Indian Journal of Pharmaceutical Education and Research, 60(1S), s33–s41. https://doi.org/10.5530/ijper.20260468