Volume 60, Issue 3

Mohamad Qutboddin, Syed Sagheer Ahmed, Nahid Abbas, Mohammad Ali, Bharathi Doddla Raghunathanaidu

pp. 918–924 · DOI: 10.5530/ijper.20262583 · 2026

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by the depletion of dopamine neurotransmitters and receptors. Although the etiology of PD is multifactorial, emerging evidence suggests that Traumati…

Pratik Vediya, Dharmik Mehta, Jemini Pandya, Sarah Gadavala, Medha Bhatiprollu, Vasanthi Aerukala

pp. 925–936 · DOI: 10.5530/ijper.20262917 · 2026

Biomimetic polymers are increasingly being explored in advanced drug and gene delivery research due to their ability to imitate the structure and function of natural biological systems. Increased biocompatibility, target…

Shailendra Sanjay Suryawanshi, Mahesh Palled, Meenaxi Maste, Parixit Bhandurge, Archana Patil, Bhuvaneshwari Sharrannavar, Ramesh Bhandari, Siddhesh Bandekar, Adarsh Arun Patil

pp. 937–945 · DOI: 10.5530/ijper.20263402 · 2026

Pharmaceutical education has undergone a paradigm shift from traditional didactic instruction to more interactive, learner-centered approaches. This review explores modern pedagogical methods and presents real-world case…

Priyadarshini Banerjee, Kishanta Kumar Pradhan

pp. 946–955 · DOI: 10.5530/ijper.20264229 · 2026

Background: Anti-oxidants are vital in maintaining cellular homeostasis by neutralizing Reactive Oxygen Species (ROS) and mitigating oxidative stress. This review aims to explore their role in disease modulation, with a …

Neelesh Malviya, Harshal Deshmukh, Rajiv Saxena, Sapna Malviya

pp. 967–984 · DOI: 10.5530/ijper.20262556 · 2026

The ZED (Zero Defect Zero Effect) Certification is an initiative aimed at enhancing the performance and sustainability of Small and Medium Enterprises (SMEs) in India. It focuses on promoting high-quality production, min…

Mukesh Rani, Seema Rohilla, Sangeet Sharma, Twinkle Chadda

pp. 985–998 · DOI: 10.5530/ijper.20261604 · 2026

Background and purpose: This study aimed for systemic and sustained delivery of drug via non-parental route. Materials and Methods: Transdermal patches were prepared by using solvent evaporation method and optimized usin…

Abhish Jadhav, Mrudula Bele

pp. 999–1012 · DOI: 10.5530/ijper.20261979 · 2026

Aim: This study aimed to develop and evaluate Memantine-PEGylated-PLGA Liposomal Formulation for Nose-to-Brain Delivery in Alzheimers Disease: A Quality-by-Design (QbD) Approach. Background: Alzheimer’s disease is a prog…

Sruthy Prathap, Rajesh Kashyap Shankar, Nebu George Thomas, Jayachandran Venkatesan, Binsi Puthanpurakkal Kizhakkethil, Suprith Surya, Prathap Mulackal Sreekantantan

pp. 1013–1020 · DOI: 10.5530/ijper.20261992 · 2026

Aim/Background: Collagen and hydroxyapatite have been used as scaffold for bone repair encouraging cell adhesion and growth. Composites synthesized from hydroxyapatite and collagen mimic biomechanical properties of natur…

Kunderu Ravi Shankar, Raghavendra Kumar Gunda, Rayavarapu Sanjay Babu, Pothuri Srinivasa Eswar, Sathvika Avvari, Kollipara Naga Venkata Chenchu Lakshmi, Shaik Aminabee

pp. 1021–1025 · DOI: 10.5530/ijper.20262850 · 2026

Objectives: Purpose of present research study was to use Ondansetron to develop a film that dissolves quickly. Materials and Methods: HPMC E5 and Primojel were used in different ratios to prepare oral dissolving films. T…

Muggu Sankara Bhavani, Ravindran Saravanan

pp. 1026–1036 · DOI: 10.5530/ijper.20263497 · 2026

Background/Objectives: Gliclazide is one of the commonly used oral anti-diabetic agents. It suffers limited and variable bioavailability due to poor solubility and intra- and inter-subject variability. The prime objectiv…

Raghwendra Waghmode, Rushikesh Hingmire, Veerendra Yeligar, Sandeep Barde

pp. 1037–1045 · DOI: 10.5530/ijper.20266552 · 2026

Aim/Background: Ornidazole is primarily used to treat peptic ulcer. Ornidazole laden floating microspheres were developed to boost bioavailability of the therapeutic moiety and its appropriate therapeutic performance. Ma…

Shyam Nikethen Girivasan, Sabeel Salam, Mohammed Fazil Rayamarakkarveettil Musthafa, Zakir Hussain Kovval Peedikayil, Akza Marium Reji, Manojkumar Venkatesan

pp. 1046–1051 · DOI: 10.5530/ijper.20261523 · 2026

Background: The aim of this paper is to describe the advancement in dermal drug delivery employing microspheres as the method, focusing on the synthesis of microspheres by solvent evaporation technique to be formulated i…

Tanushree Chakraborty, Suma. R, Aisha Khanum, Tahir Ahmed Khan, Sarvar Khan

pp. 1052–1060 · DOI: 10.5530/ijper.20261515 · 2026

Aim: Angina is a clinical syndrome with symptoms attributed to myocardial ischaemia. There are many class of drugs which are used to manage it, among such is ranolazine which acts by inhibiting late Na+ current. Ranolazi…

Anilkumar Vadaga, Santosh Kumar Rada

pp. 1061–1069 · DOI: 10.5530/ijper.20261525 · 2026

Background: The BCS Class-II faces major challenge, low solubility and poor bioavailability issues. Carvedilol, an anti-hypertensive drugs, has a bioavailability 20-25%. Objectives: This research focuses on the developme…

Qingwu Wang, Yu Huang, Jin Li, Xiang Li

pp. 1070–1080 · DOI: 10.5530/ijper.20261577 · 2026

Background: Psoralen, a naturally derived compound, is known for its anti-inflammatory properties and thus it is essential to evaluate its effects on inflammatory pathways in Rheumatoid Arthritis (RA). Aim: To assess the…

Sandhya Vasanth, Amal Fahma, Saptami Kanekar, Rajesh Raju, Niyas Rehman, Mohammed Gulzar Ahmed

pp. 1081–1095 · DOI: 10.5530/ijper.20263322 · 2026

Background: Acne vulgaris is a dermatological condition involving sebaceous gland dysfunction and is characterized by excess sebum secretion, follicular hyperkeratinization, bacterial growth, and inflammation. Curcuma ar…

Mei Wu, QinJian Xia, Lihui Liu, Le Kang

pp. 1096–1112 · DOI: 10.5530/ijper.20261749 · 2026

Background: Juglone, a naturally occurring naphthoquinone, has been recognized for its potential anticancer properties. Recent advances in network pharmacology allow for the systematic elucidation of complex molecular in…

Pawan Kumar Goswami, Sandip Chatterjee

pp. 1113–1130 · DOI: 10.5530/ijper.20261722 · 2026

Background and Aim: To perform HPLC-based phytochemical profiling and untargeted proteomic analysis of ethanolic extracts from Punica granatum, and evaluate their cytotoxic activity against MCF-7 and C6 cancer cell lines…

Yanqiu Li, Chenhui Zhao, Yanling Ren, Liping Xie

pp. 1131–1142 · DOI: 10.5530/ijper.20262481 · 2026

Background: Breast Cancer (BC) remains a major global health challenge, necessitating novel treatment approaches to improve therapeutic outcomes. Angelica dahurica, a traditional medicinal plant, contains phytochemicals …

Pratiksha Shewale, Ziyaurrahman Ataurrahman, Yash Bachhav, Kavita Bhavar, Yogesh Ahire, Vinod Bairagi

pp. 1143–1151 · DOI: 10.5530/ijper.20261638 · 2026

Background: In this investigation, the consequences of standardized ethanolic extracts of curcumin and Dioscorea alata L. To assess their therapeutic potential individually and together in spleen poisoning caused by anil…