Volume 55, Issue 3S

2021 · pp. S733–S741 · 23 articles

Volume: 55
Issue: 3S
Published: 2021
Pages: S733–S741
Articles: 23
Sections: 1
ISSN: Online - 0019-5464
Journal: IJPER

Original Article

In this issue

Original Article

Article
Formulation of Resveratrol Nanoemulsion by Phase Inversion Technique and Evaluation of Anti-Cancer Activity on Human Colon Cancer Cell Lines
Sabna Kotta
pp. s623–s629 · DOI: 10.5530/ijper.55.3s.168 · Published 2021
Colorectal cancer is in third place among the most usually detected cancer worldwide. Many natural compounds have been proved for its efficacy in the treatment of different types of carcinomas. Resveratrol a polyphenolic…
Article
Knowledge and Attitude toward the Therapeutic Potential of Human Amnion Stem Cells among Students of Taif University, Saudi Arabia
Majid Alhomrani, Abdulhakeem S. Alamri, Walaa F. Alsanie, Bassem M. Raafat, Tariq Altalhi, Nujood S. Alotaibi, Fay T. Algthami, Reyouf H. Alsalmi, Najwa H. Alhalifi, Syed Mohammed Basheeruddin Asdaq, Nagaraja Sreeharsha
pp. s630–s636 · DOI: 10.5530/ijper.55.3s.169 · Published 2021
Background: Among the various types of stem cells which have been suggested for therapeutic purposes, human amnion epithelial cells (hAEC) are highly promising. Purpose: This study aims to assess the knowledge and attitu…
Article
Self-reported Anxiety and Coping: A Cross-Sectional Study among Saudi Nursing Students during COVID-19 Pandemic using GAD-7 and Briefcope
Mohammed Asad, Atallah Alenezi, Mohammed Nasser Alsalowly, Syed Mohammed Basheeruddin Asdaq, Abdulhakeem S. Alamri, Walaa F. Alsanie, Majid Alhomrani, Yahya Mohzari, Ahmed Alrashed, Ibraheem N. Shammakhi, Muath F. Almutairi, Norah N. Aldhawyan, Mansour A. Alharbi, Omar O. Alsallami, Nagaraja Sreeharsha
pp. s637–s645 · DOI: 10.5530/ijper.55.3s.170 · Published 2021
Background: Anxiety is seen among students even during normal times. The COVID 19pandemic is believed to have increased anxiety and depression among the students. Purpose: An investigation was done to assess the anxiety …
Article
Titration of Antibodies and Application of the KAP Strategy for Hepatitis B in Students and Teachers
Nagaraja Sreeharsha, Itzjak Kadar Epstein, Syed Mohammed Basheeruddin Asdaq, Abdulhakeem S. Alamri, Walaa F. Alsanie, Majid Alhomrani
pp. s646–s651 · DOI: 10.5530/ijper.55.3s.171 · Published 2021
Aim: Hepatitis B can be prevented through a complete vaccination scheme. In clinical practice, dentistry personnel is 6 times more likely to get this disease than people who perform other activities. To determine the lev…
Article
Pharmacy Educationists on Post-COVID-19: A Lockdown Exit Preparedness Survey
Satyanarayan Pattnaik, Varun Talla, Qaiser Jahan, Kalpana Swain, JV Rao
pp. s652–s663 · DOI: 10.5530/ijper.55.3s.172 · Published 2021
Purpose: Most of the educational institutions are now closed in many parts of the world due to the pandemic outbreak of COVID-19. Rebooting the institutions, at the times when an effective therapy or vaccine is still awa…
Article
Interactive Teaching in Higher Education for Effective Knowledge Dissemination and Improved Student Participation
Atmaram P. Pawar, Vividha V. Dhapte-Pawar, Vinod L. Gaikwad
pp. S664–S671 · DOI: 10.5530/ijper.55.3s.173 · Published 2021
The present generation of students has information at their hands with the advances in technology. The conventional teaching in monologue manner, just delivering bookish information and dictation are ineffective to incul…
Article
Enhancement of Solubility and Dissolution Rate of Atazanavir Sulfate by Nanocrystallization
Vedanshu Malviya, Prashant Burange, Yashdeepsingh Thakur, Mukund Tawar
pp. S672–S680 · DOI: 10.5530/ijper.55.3s.174 · Published 2021
Objectives: The current objective of the present study was to enhance the solubility and dissolution rate of the antiviral drug atazanavir sulphate by employing nanocrystallization technique. Materials and Methods: The m…
Article
HPMC Polymers and Xanthan Gum Assisted Development and Characterization of Stavudine Extended Release Floating Tablets
Purushottam Shridhar Gangane, Tejas Pachpute, Debarshi Kar Mahapatra, Nilesh Manoharrao Mahajan
pp. S681–S692 · DOI: 10.5530/ijper.55.3s.175 · Published 2021
Objectives: Stavudine has a low half-life of 0.8-1.5 hr and therefore needs recurrent administration to sustain stable beneficial drug plasma levels. In order to enhance and preserve the stable drug level of stavudine fo…
Article
Thermodynamic Study on Hydrotropic Aggregation Behavior of Theophylline
Chinnakannu Jayakumar, D.M Reddy Prasad
pp. S693–S699 · DOI: 10.5530/ijper.55.3s.176 · Published 2021
Objectives: A systematic study is required to enhance the solubility of insoluble fluid drugs that are only sparingly soluble. Hydrotropy may be a distinctive development to reinforce the liquid solubility of poorly wate…
Article
Forced Degradation Studies of Drospirenone: Isolation and Characterization of Degradation Products
Shubhangi Bhaskarrao Sutar, Veerendra Channabasappa Yeligar, Sachinkumar Vasantrao Patil
pp. S700–S708 · DOI: 10.5530/ijper.55.3s.177 · Published 2021
Aim and Objectives: To remain safe for further processing or human consumption, study of stressed degradation for the identification of feasible degradants is required. The stability indicating high performance thin laye…
Article
In-vivo Pharmacokinetic Study, in-vitro Cytotoxic, Cell Cycle Arresting and Proapoptotic Characteristics of Multiple Emulsions for the Co-delivery of Simvastatin and Alendronate Sodium
Sandip Akaram Bandgar, Namdeo Ramhari Jadhav
pp. S709–S721 · DOI: 10.5530/ijper.55.3s.178 · Published 2021
Purpose: Development of nanocarriers that can provide efficient co-delivery of immiscible hydrophilic/ hydrophobic drugs with established technology for industrial production is crucial. Due to this reason, multiple emul…
Article
Detailed Research on a Comparative Evaluation of Diclofenac Sodium Tablets Manufactured by Using DC Grade Excipients and Wet Granulation Methods
Divya Dhatri Kara, Hemanth Katta Govindarajulu, Hemamanjushree Shivaprasad, Vamshi Krishna Tippavajhala, Mahendra Joshi, Girish Pai Kulyadi
pp. S722–S732 · DOI: 10.5530/ijper.55.3s.179 · Published 2021
Aim: The foremost aim of the present study was to formulate a Diclofenac Sodium tablet of 50mg using the direct compression method with directly compressible (DC) grade excipient and the wet granulation method. Materials…
Article
Mucoadhesive Microspheres of Atorvastatin Calcium: Rational Design, Evaluation and Enhancement of Bioavailability
Hitesh Kumar Dewangan, Arpana Sharma, Ankit Mishra, Pradeep Singour
pp. S733–S741 · DOI: 10.5530/ijper.55.3s.180 · Published 2021
Background: Atorvastatin Calcium (ATC) used for lowering the cholesterol levels in body. It is competitive inhibitor of hydroxyl methylglutaryl-coenzyme A (HMG-CoA) reductase, followed mevalonate pathway, which have low …
Article
Anti-metastatic and Anticancer Potentials of Synthesized Chalcones in B16-F10 Melanoma Cells Induced Metastatic Lung Cancer in C57BL/6 Mice
Nitesh Kumar, Nunsavath Kishan, Subhankar Biswas, Karthik Gourishetti, Mehnaz Kamal, Mallikarjuna Rao Chamallamudi
pp. S742–S750 · DOI: 10.5530/ijper.55.3s.181 · Published 2021
Aim/Background: Metastasis is the main reason of death in cancer with a key challenge to target it precisely by the available treatments. The current study was designed to assess the anti-metastatic potentials of the syn…
Article
An Experimental Model to Induce Homogeneous and Progressive Pulmonary Fibrosis in Rats
Syed Mohammad Abdullah, Papiya Mitra Mazumder
pp. S751–S764 · DOI: 10.5530/ijper.55.3s.182 · Published 2021
Background: This study aims to develop a new experimental model of pulmonary fibrosis (PF) as an alternative to conventional bleomycin model to overcome its limitations and effectively screened the therapeutic agents. Si…
Article
The Effect of Taxifolin on Acrylamide-induced Oxidative and Proinflammatory Brain Injury in Rats: A Biochemical and Histopathological Study
Alevtina Ersoy, Hasan Yasar, Ceyda Tanoglu, Gulce Naz Yazici, Taha Abdulkadir Coban, Yusuf Kemal Arslan, Halis Suleyman
pp. S765–S773 · DOI: 10.5530/ijper.55.3s.183 · Published 2021
Purpose: Acrylamide is a well-known environmental toxic compound. Taxifolin belongs to the group of flavonoids that have antioxidant, antimicrobial, anti-inflammatory and anti-carcinogenic properties. In this study, we i…
Article
Evaluation of the Antidote Activity of Nimbu swarasa (Citrus limon Linn.) on Jayapala Seed (Croton tiglium Linn.) Induced Toxicity in Wistar Albino Rats
Mouneshwari, Ravi Mundugaru, Shobha Bhat Kodavoor
pp. S774–S783 · DOI: 10.5530/ijper.55.3s.184 · Published 2021
Background: Seeds of Jayapala (Croton tiglium Linn.) is a toxic compound which is commonly used in several Ayurvedic formulations following proper detoxification methods as mentioned in the Ayurvedic classics. Adarsha ni…
Article
Preparation and Standardization of Vaginal Suppository from Punica granatum Flower Extract Known as “Golnar” in Persian Medicine
Shamim Fayazmanesh, Tayebeh Toliyat, Mahdieh Eftekhari, Gholamreza Amin, Mannan Hajimahmoodi, Mahnaz Khanavi
pp. S784–S789 · DOI: 10.5530/ijper.55.3s.185 · Published 2021
Background: Punica granatum L. flower, known as “Persian Golnar”, is used in Persian medicine to treat excessive menstrual bleeding. Most therapeutic activities of pomegranate are due to the presence of phenolic compound…
Article
Neuroprotective Effect of Bauhinia variegata Leaf Extract against Colchicine: An Experimental Study on Cognitive Dysfunction and Biochemical Alterations in Mice
Pragati Khare, Kamal Kishore, Dinesh Kumar Sharma
pp. S798–S806 · DOI: 10.5530/ijper.55.3s.187 · Published 2021
Objectives: To study the protective role of Bauhinia variegata ethanolic leaf extract induced by colchicine cognitive dysfunction and the damage of oxidative in Swiss albino mice; to examine the neuroprotective consequen…
Article
Synthesis, Cytotoxic and Antihyperlipidemic Activities of Some New coumarinyl 4-Thiazolidinone Derivatives
Katte Ishwar Bhat, Abhishek Kumar, Pankaj Kumar
pp. S807–S813 · DOI: 10.5530/ijper.55.3s.188 · Published 2021
Background: Despite tremendous advancements both in early diagnosis and approaches to treatment, cancer still remains an unconquered problem. The development of new chemotherapeutic agents for the treatment of cancer wit…
Article
Bio-Analytical Method Development for Estimation of Levofloxacin: Application in Estimation of Drug in Nano-formulations and Pharmacokinetic Studies
Priyanka Maurya, Abhiram Kumar, Samipta Singh, Raquibun Nisha, Ravi Raj Pal, Manish Kumar Chourasia, Shubhini Awasthi Saraf
pp. S814–S824 · DOI: 10.5530/ijper.55.3s.189 · Published 2021
Aim/Background: Levofloxacin is a safe antibiotic for various inflammatory disorders and a rapid analytical method for various samples reduces the estimation time as well as injects efficiency in the system. The develope…
Article
Development and Validation of a Rapid and Sensitive Stability-indicating RP-HPLC Method for Resveratrol Quantification in Pharmaceutical Formulation
Shivaprasad Gadag, Reema Narayan, Chetan Hasmukh Mehta, Akhil Suresh, Usha Yogendra Nayak
pp. S825–S836 · DOI: 10.5530/ijper.55.3s.190 · Published 2021
Background: Trans-resveratrol (RVT) is a phytoconstituent belonging to the family of polyphenols, extensively studied for its numerous health benefits. However, its susceptibility for photolytic, oxidative, and hydrolyti…
Article
Simultaneous Estimation of Pregabalin and Etoricoxib using Novel HPLC Method: An Application in Quantitative Analysis of Pharmaceutical Dosage Forms
Amit Chaudhary, Bhuvnesh Kumar Singh
pp. S837–S843 · DOI: 10.5530/ijper.55.3s.191 · Published 2021
Introduction: A new optimised method was developed for simultaneous estimation of new FDA approved drugs using RP-HPLC method that would emphasize the use of these drugs in various industries for quality measurements. Ob…